risperidone-7449 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the risperidone-7449 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AFF1 AF4/FMR2 family, member 1
AIM1L absent in melanoma 1-like
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
AQP3 aquaporin 3 (Gill blood group)
AQP7 aquaporin 7
ARHGAP35 Rho GTPase activating protein 35
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BEGAIN brain-enriched guanylate kinase-associated
BGN biglycan
BMP6 bone morphogenetic protein 6
CALCR calcitonin receptor
CCDC28B coiled-coil domain containing 28B
CD4 CD4 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP164 centrosomal protein 164kDa
CFAP69 cilia and flagella associated protein 69
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN15 claudin 15
CLEC11A C-type lectin domain family 11, member A
CORT cortistatin
CPQ carboxypeptidase Q
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
EHBP1L1 EH domain binding protein 1-like 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EMP1 epithelial membrane protein 1
ETV7 ets variant 7
FAM155A family with sequence similarity 155, member A
FAM212B family with sequence similarity 212, member B
FGFR1 fibroblast growth factor receptor 1
FGFR4 fibroblast growth factor receptor 4
FLJ11710 uncharacterized protein FLJ11710
GK2 glycerol kinase 2
GNAS GNAS complex locus
GPR153 G protein-coupled receptor 153
GRTP1 growth hormone regulated TBC protein 1
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
JAM3 junctional adhesion molecule 3
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNK12 potassium channel, two pore domain subfamily K, member 12
KRIT1 KRIT1, ankyrin repeat containing
MAP4 microtubule-associated protein 4
MAPK12 mitogen-activated protein kinase 12
MEF2C myocyte enhancer factor 2C
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MXD4 MAX dimerization protein 4
MYCNOS MYCN opposite strand
NIPAL2 NIPA-like domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR1H2 nuclear receptor subfamily 1, group H, member 2
OPCML opioid binding protein/cell adhesion molecule-like
PAOX polyamine oxidase (exo-N4-amino)
PARD6B par-6 family cell polarity regulator beta
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDAP1 PDGFA associated protein 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PODNL1 podocan-like 1
POMT2 protein-O-mannosyltransferase 2
PSG9 pregnancy specific beta-1-glycoprotein 9
RAB36 RAB36, member RAS oncogene family
RARA retinoic acid receptor, alpha
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBM5 RNA binding motif protein 5
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNFT2 ring finger protein, transmembrane 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPS28 ribosomal protein S28
SCNN1B sodium channel, non voltage gated 1 beta subunit
SIGLEC8 sialic acid binding Ig-like lectin 8
SKI SKI proto-oncogene
SLC12A8 solute carrier family 12, member 8
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A14 solute carrier family 22, member 14
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMG6 SMG6 nonsense mediated mRNA decay factor
SOCS3 suppressor of cytokine signaling 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
STAT5B signal transducer and activator of transcription 5B
TDRD3 tudor domain containing 3
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM2 transmembrane protein 2
TNS1 tensin 1
TTC38 tetratricopeptide repeat domain 38
TTC9 tetratricopeptide repeat domain 9
VASH2 vasohibin 2
VSNL1 visinin-like 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBED1 zinc finger, BED-type containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF177 zinc finger protein 177
ZNF75D zinc finger protein 75D
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACVR2B activin A receptor, type IIB
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKRD36 ankyrin repeat domain 36
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ARRB2 arrestin, beta 2
BCAS1 breast carcinoma amplified sequence 1
BCCIP BRCA2 and CDKN1A interacting protein
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CCDC91 coiled-coil domain containing 91
CCNJ cyclin J
CCNO cyclin O
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK3 cyclin-dependent kinase 3
CLASP1 cytoplasmic linker associated protein 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
DCK deoxycytidine kinase
DNAL4 dynein, axonemal, light chain 4
DSN1 DSN1, MIS12 kinetochore complex component
ERO1L ERO1-like (S. cerevisiae)
EXOC5 exocyst complex component 5
FAM192A family with sequence similarity 192, member A
FKBPL FK506 binding protein like
FSD1 fibronectin type III and SPRY domain containing 1
FUZ fuzzy planar cell polarity protein
GAB2 GRB2-associated binding protein 2
GPR27 G protein-coupled receptor 27
GPR87 G protein-coupled receptor 87
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H2AG histone cluster 1, H2ag
HIST1H2BF histone cluster 1, H2bf
HIST1H4J histone cluster 1, H4j
IFT22 intraflagellar transport 22
IL4R interleukin 4 receptor
IRF9 interferon regulatory factor 9
KIAA0513 KIAA0513
KIF18A kinesin family member 18A
KLHDC4 kelch domain containing 4
L2HGDH L-2-hydroxyglutarate dehydrogenase
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC20 leucine rich repeat containing 20
LRRC8E leucine rich repeat containing 8 family, member E
LY6G5C lymphocyte antigen 6 complex, locus G5C
MBIP MAP3K12 binding inhibitory protein 1
MBNL3 muscleblind-like splicing regulator 3
MICU1 mitochondrial calcium uptake 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MORC3 MORC family CW-type zinc finger 3
MTMR11 myotubularin related protein 11
NES nestin
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NLK nemo-like kinase
NPY5R neuropeptide Y receptor Y5
OCEL1 occludin/ELL domain containing 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARP16 poly (ADP-ribose) polymerase family, member 16
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLA2G15 phospholipase A2, group XV
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRSS8 protease, serine, 8
PTCD2 pentatricopeptide repeat domain 2
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33B RAB33B, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBL1 retinoblastoma-like 1
RPL13P5 ribosomal protein L13 pseudogene 5
RPUSD2 RNA pseudouridylate synthase domain containing 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC35F5 solute carrier family 35, member F5
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SNHG20 small nucleolar RNA host gene 20
SP140L SP140 nuclear body protein-like
STARD13 StAR-related lipid transfer (START) domain containing 13
TM7SF3 transmembrane 7 superfamily member 3
TMEM254 transmembrane protein 254
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBE2L6 ubiquitin-conjugating enzyme E2L 6
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR18 WD repeat domain 18
XPA xeroderma pigmentosum, complementation group A
ZBTB10 zinc finger and BTB domain containing 10
ZFYVE16 zinc finger, FYVE domain containing 16
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF557 zinc finger protein 557
ZNF586 zinc finger protein 586
ZNF623 zinc finger protein 623
ZNF672 zinc finger protein 672
ZNF83 zinc finger protein 83