A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation. (Gene Ontology, GO_0016442)
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10 proteins localized to the risc complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.