rifampicin-4126 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the rifampicin-4126 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADAM22 ADAM metallopeptidase domain 22
ADAP2 ArfGAP with dual PH domains 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDOB aldolase B, fructose-bisphosphate
ARSD arylsulfatase D
ATXN2L ataxin 2-like
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK1D calcium/calmodulin-dependent protein kinase ID
CD8A CD8a molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CLDN11 claudin 11
CPB1 carboxypeptidase B1 (tissue)
CREBZF CREB/ATF bZIP transcription factor
CRHR1 corticotropin releasing hormone receptor 1
CRY2 cryptochrome circadian clock 2
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDNRA endothelin receptor type A
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ESR1 estrogen receptor 1
ETV7 ets variant 7
FAIM2 Fas apoptotic inhibitory molecule 2
FBN2 fibrillin 2
FBXO21 F-box protein 21
FLOT1 flotillin 1
FST follistatin
GJA9 gap junction protein, alpha 9, 59kDa
GLP1R glucagon-like peptide 1 receptor
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPR137 G protein-coupled receptor 137
GPR143 G protein-coupled receptor 143
GPR161 G protein-coupled receptor 161
GPR176 G protein-coupled receptor 176
HIST1H1B histone cluster 1, H1b
HLA-DRA major histocompatibility complex, class II, DR alpha
HOXA10 homeobox A10
HPX hemopexin
HSPG2 heparan sulfate proteoglycan 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1456 KIAA1456
LRP12 low density lipoprotein receptor-related protein 12
MAGEA12 melanoma antigen family A12
MARK2 MAP/microtubule affinity-regulating kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MEFV Mediterranean fever
MFSD6 major facilitator superfamily domain containing 6
MTAP methylthioadenosine phosphorylase
MX2 MX dynamin-like GTPase 2
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NF2 neurofibromin 2 (merlin)
NOL10 nucleolar protein 10
NR6A1 nuclear receptor subfamily 6, group A, member 1
PARG poly (ADP-ribose) glycohydrolase
PCDHB13 protocadherin beta 13
PCDHGA8 protocadherin gamma subfamily A, 8
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCD1 phospholipase C, delta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
POU3F4 POU class 3 homeobox 4
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRB3 proline-rich protein BstNI subfamily 3
PRDX2 peroxiredoxin 2
RASIP1 Ras interacting protein 1
SATB2 SATB homeobox 2
SDS serine dehydratase
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHOX2 short stature homeobox 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SOX15 SRY (sex determining region Y)-box 15
SPEG SPEG complex locus
SPRR2B small proline-rich protein 2B
SSPN sarcospan
STAT4 signal transducer and activator of transcription 4
TBC1D2 TBC1 domain family, member 2
TBL1Y transducin (beta)-like 1, Y-linked
TCF3 transcription factor 3
TEX14 testis expressed 14
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TOR4A torsin family 4, member A
TOX thymocyte selection-associated high mobility group box
TRIM44 tripartite motif containing 44
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSC2 tuberous sclerosis 2
TUBA3C tubulin, alpha 3c
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UHRF1BP1L UHRF1 binding protein 1-like
VN1R1 vomeronasal 1 receptor 1
ZNF682 zinc finger protein 682
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASIC3 acid sensing (proton gated) ion channel 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B9D2 B9 protein domain 2
BCORL1 BCL6 corepressor-like 1
C10ORF95 chromosome 10 open reading frame 95
C14ORF79 chromosome 14 open reading frame 79
C7ORF69 chromosome 7 open reading frame 69
CCNO cyclin O
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLCN2 chloride channel, voltage-sensitive 2
CLGN calmegin
CORT cortistatin
CUL9 cullin 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DENND5B DENN/MADD domain containing 5B
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK5 docking protein 5
EN2 engrailed homeobox 2
ENO2 enolase 2 (gamma, neuronal)
EPX eosinophil peroxidase
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL2 F-box and leucine-rich repeat protein 2
FBXL8 F-box and leucine-rich repeat protein 8
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
FLJ21369 uncharacterized protein FLJ21369
FOXN2 forkhead box N2
FRMD1 FERM domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR182 G protein-coupled receptor 182
GRB7 growth factor receptor-bound protein 7
GRIP2 glutamate receptor interacting protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HCFC1 host cell factor C1
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AK histone cluster 1, H2ak
HMOX1 heme oxygenase 1
IFITM1 interferon induced transmembrane protein 1
IGFLR1 IGF-like family receptor 1
IQCG IQ motif containing G
KCNK10 potassium channel, two pore domain subfamily K, member 10
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT83 keratin 83, type II
LARP6 La ribonucleoprotein domain family, member 6
LIN7B lin-7 homolog B (C. elegans)
LINC00597 long intergenic non-protein coding RNA 597
LMTK2 lemur tyrosine kinase 2
LZTR1 leucine-zipper-like transcription regulator 1
MAPK8 mitogen-activated protein kinase 8
MED15 mediator complex subunit 15
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MST1 macrophage stimulating 1
NARFL nuclear prelamin A recognition factor-like
NIPAL2 NIPA-like domain containing 2
NPY4R neuropeptide Y receptor Y4
NPY6R neuropeptide Y receptor Y6 (pseudogene)
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE8B phosphodiesterase 8B
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
POM121L2 POM121 transmembrane nucleoporin-like 2
POPDC3 popeye domain containing 3
PORCN porcupine homolog (Drosophila)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PROL1 proline rich, lacrimal 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB3A RAB3A, member RAS oncogene family
RNF121 ring finger protein 121
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
SAMD9 sterile alpha motif domain containing 9
SCN10A sodium channel, voltage gated, type X alpha subunit
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SNTA1 syntrophin, alpha 1
SPAG4 sperm associated antigen 4
TARP TCR gamma alternate reading frame protein
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TH tyrosine hydroxylase
TMEM254 transmembrane protein 254
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS2 tensin 2
TRAIP TRAF interacting protein
TWF2 twinfilin actin binding protein 2
VIM vimentin
ZNF282 zinc finger protein 282
ZNF304 zinc finger protein 304