rifampicin-2487 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the rifampicin-2487 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADARB1 adenosine deaminase, RNA-specific, B1
ADCK2 aarF domain containing kinase 2
ADCK4 aarF domain containing kinase 4
AP1M2 adaptor-related protein complex 1, mu 2 subunit
APC adenomatous polyposis coli
ARHGAP44 Rho GTPase activating protein 44
ARMC4 armadillo repeat containing 4
BCL2 B-cell CLL/lymphoma 2
BRS3 bombesin-like receptor 3
C21ORF2 chromosome 21 open reading frame 2
C22ORF31 chromosome 22 open reading frame 31
CADM3 cell adhesion molecule 3
CDC42 cell division cycle 42
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CFAP69 cilia and flagella associated protein 69
CHPF chondroitin polymerizing factor
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLEC4A C-type lectin domain family 4, member A
CNOT2 CCR4-NOT transcription complex, subunit 2
CNTN5 contactin 5
CPB1 carboxypeptidase B1 (tissue)
CSNK1E casein kinase 1, epsilon
CTSZ cathepsin Z
CUL7 cullin 7
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCT dopachrome tautomerase
DLX2 distal-less homeobox 2
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DTX2 deltex 2, E3 ubiquitin ligase
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
ENG endoglin
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPX eosinophil peroxidase
EXOG endo/exonuclease (5'-3'), endonuclease G-like
EXT1 exostosin glycosyltransferase 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFBP1 fibroblast growth factor binding protein 1
FLOT1 flotillin 1
FZD4 frizzled class receptor 4
GBP1 guanylate binding protein 1, interferon-inducible
GP5 glycoprotein V (platelet)
HIPK3 homeodomain interacting protein kinase 3
HOXC11 homeobox C11
ING1 inhibitor of growth family, member 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLF12 Kruppel-like factor 12
KLF3 Kruppel-like factor 3 (basic)
KLK13 kallikrein-related peptidase 13
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LARGE like-glycosyltransferase
LIMD1 LIM domains containing 1
LIMS2 LIM and senescent cell antigen-like domains 2
LMF1 lipase maturation factor 1
MED16 mediator complex subunit 16
METTL7A methyltransferase like 7A
MMP25 matrix metallopeptidase 25
MRPL44 mitochondrial ribosomal protein L44
MUC3A mucin 3A, cell surface associated
MYO1E myosin IE
MYOZ2 myozenin 2
NEUROD4 neuronal differentiation 4
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NNAT neuronatin
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP88 nucleoporin 88kDa
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OSR2 odd-skipped related transciption factor 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PDLIM4 PDZ and LIM domain 4
PER3 period circadian clock 3
PLAT plasminogen activator, tissue
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PTGES2 prostaglandin E synthase 2
RAB11B RAB11B, member RAS oncogene family
RRBP1 ribosome binding protein 1
RUNX2 runt-related transcription factor 2
SCN5A sodium channel, voltage gated, type V alpha subunit
SLAMF7 SLAM family member 7
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC16A4 solute carrier family 16, member 4
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TAPT1 transmembrane anterior posterior transformation 1
TBX2 T-box 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TOM1 target of myb1 (chicken)
TONSL tonsoku-like, DNA repair protein
TTLL1 tubulin tyrosine ligase-like family member 1
TTLL7 tubulin tyrosine ligase-like family member 7
ULBP2 UL16 binding protein 2
ULK4 unc-51 like kinase 4
WNT16 wingless-type MMTV integration site family, member 16
WRAP53 WD repeat containing, antisense to TP53
ZER1 zyg-11 related, cell cycle regulator
ZFHX3 zinc finger homeobox 3

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARL15 ADP-ribosylation factor-like 15
B9D2 B9 protein domain 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
C16ORF59 chromosome 16 open reading frame 59
C5 complement component 5
CHM choroideremia (Rab escort protein 1)
CISH cytokine inducible SH2-containing protein
CLCF1 cardiotrophin-like cytokine factor 1
CNTN1 contactin 1
CPNE7 copine VII
CPTP ceramide-1-phosphate transfer protein
CRY2 cryptochrome circadian clock 2
CXXC4 CXXC finger protein 4
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNM3 dynamin 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOK3 docking protein 3
DPEP2 dipeptidase 2
DVL1 dishevelled segment polarity protein 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBXO31 F-box protein 31
FJX1 four jointed box 1 (Drosophila)
FOXN2 forkhead box N2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATA6 GATA binding protein 6
GLCE glucuronic acid epimerase
GMEB1 glucocorticoid modulatory element binding protein 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
GRIP2 glutamate receptor interacting protein 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HPSE heparanase
HRH2 histamine receptor H2
IL22 interleukin 22
IQCG IQ motif containing G
LATS1 large tumor suppressor kinase 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBOAT2 membrane bound O-acyltransferase domain containing 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCTP2 multiple C2 domains, transmembrane 2
MDM4 MDM4, p53 regulator
MRAS muscle RAS oncogene homolog
MREG melanoregulin
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
N4BP2L2-IT2 N4BPL2 intronic transcript 2
OCEL1 occludin/ELL domain containing 1
OXTR oxytocin receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PIPOX pipecolic acid oxidase
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
POM121 POM121 transmembrane nucleoporin
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRR14L proline rich 14-like
RAB3A RAB3A, member RAS oncogene family
REC8 REC8 meiotic recombination protein
SCUBE3 signal peptide, CUB domain, EGF-like 3
SENP7 SUMO1/sentrin specific peptidase 7
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SFT2D2 SFT2 domain containing 2
SGCE sarcoglycan, epsilon
SH3BGR SH3 domain binding glutamate-rich protein
SHARPIN SHANK-associated RH domain interactor
SNAI1 snail family zinc finger 1
STX1A syntaxin 1A (brain)
SYNC syncoilin, intermediate filament protein
TAS2R10 taste receptor, type 2, member 10
TBKBP1 TBK1 binding protein 1
TEC tec protein tyrosine kinase
TMC7 transmembrane channel-like 7
TMEM39B transmembrane protein 39B
TMEM53 transmembrane protein 53
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM25 tripartite motif containing 25
TRIM45 tripartite motif containing 45
TRPS1 trichorhinophalangeal syndrome I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA4B tubulin, alpha 4b
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF230 zinc finger protein 230
ZNF528 zinc finger protein 528
ZNF862 zinc finger protein 862