rifabutin-3873 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the rifabutin-3873 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADGRB2 adhesion G protein-coupled receptor B2
ADM adrenomedullin
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
ANG angiogenin, ribonuclease, RNase A family, 5
APLP1 amyloid beta (A4) precursor-like protein 1
ARMCX2 armadillo repeat containing, X-linked 2
BMP7 bone morphogenetic protein 7
BTN2A2 butyrophilin, subfamily 2, member A2
C19ORF66 chromosome 19 open reading frame 66
CDA cytidine deaminase
CEP112 centrosomal protein 112kDa
CLCN4 chloride channel, voltage-sensitive 4
CLGN calmegin
CORO1A coronin, actin binding protein, 1A
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DFNB31 deafness, autosomal recessive 31
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ELOVL4 ELOVL fatty acid elongase 4
EMP1 epithelial membrane protein 1
FAM105A family with sequence similarity 105, member A
FN1 fibronectin 1
FSCN1 fascin actin-bundling protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GLRX glutaredoxin (thioltransferase)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRK5 G protein-coupled receptor kinase 5
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL18 interleukin 18
ITM2C integral membrane protein 2C
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KIF5C kinesin family member 5C
LINC00341 long intergenic non-protein coding RNA 341
LRP12 low density lipoprotein receptor-related protein 12
LRRC49 leucine rich repeat containing 49
MAN1C1 mannosidase, alpha, class 1C, member 1
MAOA monoamine oxidase A
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MLF1 myeloid leukemia factor 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTSS1 metastasis suppressor 1
NIPAL3 NIPA-like domain containing 3
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRTN neurturin
PADI3 peptidyl arginine deiminase, type III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PDGFC platelet derived growth factor C
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PML promyelocytic leukemia
PPARD peroxisome proliferator-activated receptor delta
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RAB29 RAB29, member RAS oncogene family
RAI2 retinoic acid induced 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
REEP1 receptor accessory protein 1
RGCC regulator of cell cycle
RNASE4 ribonuclease, RNase A family, 4
RUNDC3B RUN domain containing 3B
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLCO4C1 solute carrier organic anion transporter family, member 4C1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT4 signal transducer and activator of transcription 4
STON1 stonin 1
TBXA2R thromboxane A2 receptor
TFEB transcription factor EB
TNIK TRAF2 and NCK interacting kinase
TTC33 tetratricopeptide repeat domain 33
TTLL7 tubulin tyrosine ligase-like family member 7
ULBP2 UL16 binding protein 2
VWA5A von Willebrand factor A domain containing 5A
ZBTB18 zinc finger and BTB domain containing 18
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF204P zinc finger protein 204, pseudogene

decreased expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
BRD9 bromodomain containing 9
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C19ORF40 chromosome 19 open reading frame 40
C9ORF114 chromosome 9 open reading frame 114
CASD1 CAS1 domain containing 1
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBX8 chromobox homolog 8
CCDC71 coiled-coil domain containing 71
CCDC94 coiled-coil domain containing 94
CDK3 cyclin-dependent kinase 3
CHRM3 cholinergic receptor, muscarinic 3
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DPY19L1P1 DPY19L1 pseudogene 1
ECHDC2 enoyl CoA hydratase domain containing 2
ESRP2 epithelial splicing regulatory protein 2
FAM155A family with sequence similarity 155, member A
FJX1 four jointed box 1 (Drosophila)
FKBP10 FK506 binding protein 10, 65 kDa
FOXC1 forkhead box C1
GPR27 G protein-coupled receptor 27
GPR87 G protein-coupled receptor 87
GSAP gamma-secretase activating protein
HIRIP3 HIRA interacting protein 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IL12RB1 interleukin 12 receptor, beta 1
INHBB inhibin, beta B
IRX5 iroquois homeobox 5
JADE2 jade family PHD finger 2
KAT2A K(lysine) acetyltransferase 2A
KDM8 lysine (K)-specific demethylase 8
KEAP1 kelch-like ECH-associated protein 1
KIAA0125 KIAA0125
KIAA0141 KIAA0141
KRT15 keratin 15, type I
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LRRC61 leucine rich repeat containing 61
LY6G5C lymphocyte antigen 6 complex, locus G5C
MCM9 minichromosome maintenance complex component 9
MEPCE methylphosphate capping enzyme
METTL1 methyltransferase like 1
METTL8 methyltransferase like 8
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDZK1 PDZ domain containing 1
PP14571 uncharacterized LOC100130449
QSER1 glutamine and serine rich 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBM23 RNA binding motif protein 23
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF220 ring finger protein 220
SARS2 seryl-tRNA synthetase 2, mitochondrial
SFMBT1 Scm-like with four mbt domains 1
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMYD5 SMYD family member 5
SNHG20 small nucleolar RNA host gene 20
SNHG3 small nucleolar RNA host gene 3
SOAT2 sterol O-acyltransferase 2
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STAG1 stromal antigen 1
STC2 stanniocalcin 2
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM39B transmembrane protein 39B
TSC22D4 TSC22 domain family, member 4
UBTF upstream binding transcription factor, RNA polymerase I
UBXN8 UBX domain protein 8
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS9D1 VPS9 domain containing 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
WDR4 WD repeat domain 4
WDR62 WD repeat domain 62
WDR74 WD repeat domain 74
ZBTB3 zinc finger and BTB domain containing 3
ZNF134 zinc finger protein 134
ZNF408 zinc finger protein 408
ZNF692 zinc finger protein 692
ZNF76 zinc finger protein 76
ZNF787 zinc finger protein 787