ricinine-2505 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the ricinine-2505 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOXE3 arachidonate lipoxygenase 3
APAF1 apoptotic peptidase activating factor 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARHGAP33 Rho GTPase activating protein 33
ARHGAP35 Rho GTPase activating protein 35
ARMCX4 armadillo repeat containing, X-linked 4
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BEND5 BEN domain containing 5
BMP8B bone morphogenetic protein 8b
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF63 chromosome 11 open reading frame 63
CA7 carbonic anhydrase VII
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD209 CD209 molecule
CDHR1 cadherin-related family member 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CGA glycoprotein hormones, alpha polypeptide
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLDN3 claudin 3
CLSTN2 calsyntenin 2
CLUL1 clusterin-like 1 (retinal)
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CRTAM cytotoxic and regulatory T cell molecule
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DAPK3 death-associated protein kinase 3
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMP1 dentin matrix acidic phosphoprotein 1
EFCAB11 EF-hand calcium binding domain 11
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF3F eukaryotic translation initiation factor 3, subunit F
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EN1 engrailed homeobox 1
EPS8L1 EPS8-like 1
FAM65A family with sequence similarity 65, member A
FBLN1 fibulin 1
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FLT1 fms-related tyrosine kinase 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
HIST1H3G histone cluster 1, H3g
IL11 interleukin 11
IL12RB1 interleukin 12 receptor, beta 1
IL22 interleukin 22
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IZUMO4 IZUMO family member 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLF12 Kruppel-like factor 12
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LIM2 lens intrinsic membrane protein 2, 19kDa
LPP LIM domain containing preferred translocation partner in lipoma
LTBP2 latent transforming growth factor beta binding protein 2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARC1 mitochondrial amidoxime reducing component 1
NCKAP1L NCK-associated protein 1-like
NDOR1 NADPH dependent diflavin oxidoreductase 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRP1 neuropilin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OTOF otoferlin
PCDH11X protocadherin 11 X-linked
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PEAK1 pseudopodium-enriched atypical kinase 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
RAB26 RAB26, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIBC2 RIB43A domain with coiled-coils 2
RPL10L ribosomal protein L10-like
RRAGB Ras-related GTP binding B
RUNDC3B RUN domain containing 3B
SCGB2A1 secretoglobin, family 2A, member 1
SH2D3A SH2 domain containing 3A
SIRT5 sirtuin 5
SKAP1 src kinase associated phosphoprotein 1
SPAG4 sperm associated antigen 4
SPHK1 sphingosine kinase 1
SYNJ1 synaptojanin 1
TADA3 transcriptional adaptor 3
TDRD1 tudor domain containing 1
TGFA transforming growth factor, alpha
THPO thrombopoietin
TLX3 T-cell leukemia homeobox 3
TM4SF4 transmembrane 4 L six family member 4
TYRO3 TYRO3 protein tyrosine kinase
YOD1 YOD1 deubiquitinase
ZER1 zyg-11 related, cell cycle regulator
ZNF235 zinc finger protein 235
ZNF280B zinc finger protein 280B
ZNF771 zinc finger protein 771
ZSWIM8 zinc finger, SWIM-type containing 8
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKRD55 ankyrin repeat domain 55
APOL6 apolipoprotein L, 6
APOLD1 apolipoprotein L domain containing 1
ARID5A AT rich interactive domain 5A (MRF1-like)
ASB13 ankyrin repeat and SOCS box containing 13
ASPN asporin
BCORL1 BCL6 corepressor-like 1
CCNT1 cyclin T1
CD70 CD70 molecule
CHML choroideremia-like (Rab escort protein 2)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CIDEC cell death-inducing DFFA-like effector c
CLCF1 cardiotrophin-like cytokine factor 1
CLEC2D C-type lectin domain family 2, member D
COL19A1 collagen, type XIX, alpha 1
CPNE7 copine VII
CTSO cathepsin O
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
ELMO3 engulfment and cell motility 3
ENO3 enolase 3 (beta, muscle)
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
FAM102A family with sequence similarity 102, member A
FAM120C family with sequence similarity 120C
FAM188A family with sequence similarity 188, member A
FKBP14 FK506 binding protein 14, 22 kDa
FKBPL FK506 binding protein like
FLRT2 fibronectin leucine rich transmembrane protein 2
GALE UDP-galactose-4-epimerase
GEMIN8 gem (nuclear organelle) associated protein 8
GLTP glycolipid transfer protein
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPATCH3 G patch domain containing 3
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCG4 HLA complex group 4 (non-protein coding)
HHLA3 HERV-H LTR-associating 3
HP haptoglobin
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD15 potassium channel tetramerization domain containing 15
KDM5C lysine (K)-specific demethylase 5C
KLF1 Kruppel-like factor 1 (erythroid)
LAX1 lymphocyte transmembrane adaptor 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPPR3 lipid phosphate phosphatase-related protein type 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LYPLA2P1 lysophospholipase II pseudogene 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MICALL2 MICAL-like 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MOSPD3 motile sperm domain containing 3
MTSS1L metastasis suppressor 1-like
MYH15 myosin, heavy chain 15
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NLK nemo-like kinase
NNAT neuronatin
NT5M 5',3'-nucleotidase, mitochondrial
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDHGB5 protocadherin gamma subfamily B, 5
PDZD7 PDZ domain containing 7
PER1 period circadian clock 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLTP phospholipid transfer protein
POLM polymerase (DNA directed), mu
PRAF2 PRA1 domain family, member 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF25 ring finger protein 25
RPA4 replication protein A4, 30kDa
RPL23AP7 ribosomal protein L23a pseudogene 7
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEPW1 selenoprotein W, 1
SLC16A6 solute carrier family 16, member 6
SNX16 sorting nexin 16
SPATA2L spermatogenesis associated 2-like
SPIDR scaffolding protein involved in DNA repair
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP3 STEAP family member 3, metalloreductase
STEAP4 STEAP family member 4
THEM6 thioesterase superfamily member 6
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TOM1 target of myb1 (chicken)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
ULK1 unc-51 like autophagy activating kinase 1
XAB2 XPA binding protein 2
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF32 zinc finger protein 32
ZNF408 zinc finger protein 408
ZNF768 zinc finger protein 768