ribostamycin-3444 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ribostamycin-3444 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM2 ADAM metallopeptidase domain 2
ADAM22 ADAM metallopeptidase domain 22
ADAM8 ADAM metallopeptidase domain 8
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
C19ORF66 chromosome 19 open reading frame 66
C19ORF73 chromosome 19 open reading frame 73
C2ORF68 chromosome 2 open reading frame 68
C8A complement component 8, alpha polypeptide
CDH8 cadherin 8, type 2
CDK10 cyclin-dependent kinase 10
CDKL3 cyclin-dependent kinase-like 3
CHKB choline kinase beta
CLCF1 cardiotrophin-like cytokine factor 1
CLEC11A C-type lectin domain family 11, member A
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL11A2 collagen, type XI, alpha 2
COL1A1 collagen, type I, alpha 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DNM3 dynamin 3
DUSP13 dual specificity phosphatase 13
EPOR erythropoietin receptor
FAM46C family with sequence similarity 46, member C
FBXO4 F-box protein 4
FGF4 fibroblast growth factor 4
FH fumarate hydratase
GJA8 gap junction protein, alpha 8, 50kDa
GK glycerol kinase
GPR137 G protein-coupled receptor 137
HDLBP high density lipoprotein binding protein
HTT huntingtin
IFNA14 interferon, alpha 14
IGHA1 immunoglobulin heavy constant alpha 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
INHA inhibin, alpha
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KRT85 keratin 85, type II
LAMC3 laminin, gamma 3
LAMP1 lysosomal-associated membrane protein 1
LHX6 LIM homeobox 6
LOC399491
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYZ lysozyme
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MATK megakaryocyte-associated tyrosine kinase
MED16 mediator complex subunit 16
MTMR7 myotubularin related protein 7
NF2 neurofibromin 2 (merlin)
OGFR opioid growth factor receptor
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAX5 paired box 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PHF20 PHD finger protein 20
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLLP plasmolipin
PQBP1 polyglutamine binding protein 1
PSD3 pleckstrin and Sec7 domain containing 3
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVR poliovirus receptor
RIN2 Ras and Rab interactor 2
RND2 Rho family GTPase 2
RNF31 ring finger protein 31
RPL18 ribosomal protein L18
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SH3BP2 SH3-domain binding protein 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTBN1 spectrin, beta, non-erythrocytic 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STX1A syntaxin 1A (brain)
TCP11L1 t-complex 11, testis-specific-like 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGM2 transglutaminase 2
TM6SF1 transmembrane 6 superfamily member 1
TMC6 transmembrane channel-like 6
TMEM209 transmembrane protein 209
TNC tenascin C
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAF2 TNF receptor-associated factor 2
UBXN1 UBX domain protein 1
WDR55 WD repeat domain 55
ZBTB7A zinc finger and BTB domain containing 7A
ZDHHC14 zinc finger, DHHC-type containing 14
ZHX3 zinc fingers and homeoboxes 3
ZNF117 zinc finger protein 117
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL15 ADP-ribosylation factor-like 15
BAG4 BCL2-associated athanogene 4
C16ORF45 chromosome 16 open reading frame 45
C1ORF109 chromosome 1 open reading frame 109
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CAPRIN2 caprin family member 2
CASZ1 castor zinc finger 1
CBR1 carbonyl reductase 1
CDC37L1 cell division cycle 37-like 1
CFAP44 cilia and flagella associated protein 44
CIR1 corepressor interacting with RBPJ, 1
CLCN2 chloride channel, voltage-sensitive 2
CLDND1 claudin domain containing 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNOT6 CCR4-NOT transcription complex, subunit 6
CNPY3 canopy FGF signaling regulator 3
CROT carnitine O-octanoyltransferase
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
DSCAM Down syndrome cell adhesion molecule
DSE dermatan sulfate epimerase
EVPL envoplakin
FA2H fatty acid 2-hydroxylase
FAAH fatty acid amide hydrolase
FAM169A family with sequence similarity 169, member A
FAM53B family with sequence similarity 53, member B
FBXW12 F-box and WD repeat domain containing 12
FCHO1 FCH domain only 1
FHOD1 formin homology 2 domain containing 1
FKBP5 FK506 binding protein 5
FRK fyn-related Src family tyrosine kinase
GBP2 guanylate binding protein 2, interferon-inducible
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HLA-J major histocompatibility complex, class I, J (pseudogene)
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1
IPP intracisternal A particle-promoted polypeptide
IRF6 interferon regulatory factor 6
KIAA0355 KIAA0355
KIF18A kinesin family member 18A
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LPCAT3 lysophosphatidylcholine acyltransferase 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBTD1 mbt domain containing 1
MCRS1 microspherule protein 1
MED9 mediator complex subunit 9
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
NABP2 nucleic acid binding protein 2
NEK11 NIMA-related kinase 11
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOTCH1 notch 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NUP62CL nucleoporin 62kDa C-terminal like
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
POTEKP POTE ankyrin domain family, member K, pseudogene
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB30 RAB30, member RAS oncogene family
RBL1 retinoblastoma-like 1
RBM28 RNA binding motif protein 28
RFTN1 raftlin, lipid raft linker 1
SAV1 salvador family WW domain containing protein 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SKA1 spindle and kinetochore associated complex subunit 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC46A3 solute carrier family 46, member 3
SOWAHC sosondowah ankyrin repeat domain family member C
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TESC tescalcin
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TLN1 talin 1
TMEM183A transmembrane protein 183A
TMEM254 transmembrane protein 254
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TSPAN14 tetraspanin 14
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
TWF2 twinfilin actin binding protein 2
UBQLN4 ubiquilin 4
ULBP2 UL16 binding protein 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR91 WD repeat domain 91
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF205 zinc finger protein 205
ZNF227 zinc finger protein 227
ZNF721 zinc finger protein 721
ZNF778 zinc finger protein 778