ribavirin-7316 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the ribavirin-7316 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
AGGF1 angiogenic factor with G patch and FHA domains 1
AGMAT agmatine ureohydrolase (agmatinase)
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALPPL2 alkaline phosphatase, placental-like 2
ARRB2 arrestin, beta 2
ARTN artemin
BTN3A1 butyrophilin, subfamily 3, member A1
C11ORF68 chromosome 11 open reading frame 68
C6ORF10 chromosome 6 open reading frame 10
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNTNAP2 contactin associated protein-like 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DENND2A DENN/MADD domain containing 2A
DVL3 dishevelled segment polarity protein 3
DZIP1 DAZ interacting zinc finger protein 1
EFNB1 ephrin-B1
EFNB3 ephrin-B3
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ELOVL5 ELOVL fatty acid elongase 5
FGF5 fibroblast growth factor 5
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FNDC4 fibronectin type III domain containing 4
FOXG1 forkhead box G1
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GAS7 growth arrest-specific 7
GCFC2 GC-rich sequence DNA-binding factor 2
GM2A GM2 ganglioside activator
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HDLBP high density lipoprotein binding protein
HOXA4 homeobox A4
HSPA2 heat shock 70kDa protein 2
IFI6 interferon, alpha-inducible protein 6
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
JUND jun D proto-oncogene
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KDM6A lysine (K)-specific demethylase 6A
LIME1 Lck interacting transmembrane adaptor 1
LNPEP leucyl/cystinyl aminopeptidase
LRP1 low density lipoprotein receptor-related protein 1
MEG3 maternally expressed 3 (non-protein coding)
MRPS18C mitochondrial ribosomal protein S18C
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYL10 myosin, light chain 10, regulatory
MYRF myelin regulatory factor
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDE1 nudE neurodevelopment protein 1
OVGP1 oviductal glycoprotein 1, 120kDa
PCDHGB5 protocadherin gamma subfamily B, 5
PDE4D phosphodiesterase 4D, cAMP-specific
PHF7 PHD finger protein 7
PLXNA3 plexin A3
PNISR PNN-interacting serine/arginine-rich protein
PRR7 proline rich 7 (synaptic)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBMS3 RNA binding motif, single stranded interacting protein 3
RGS5 regulator of G-protein signaling 5
RHO rhodopsin
RHOBTB1 Rho-related BTB domain containing 1
RPL10 ribosomal protein L10
RUNX1 runt-related transcription factor 1
SEC24D SEC24 family member D
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SENP6 SUMO1/sentrin specific peptidase 6
SETDB1 SET domain, bifurcated 1
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F6 solute carrier family 35, member F6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPTBN2 spectrin, beta, non-erythrocytic 2
STAC SH3 and cysteine rich domain
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STIM1 stromal interaction molecule 1
STS steroid sulfatase (microsomal), isozyme S
SYNJ2 synaptojanin 2
SYT17 synaptotagmin XVII
TELO2 telomere maintenance 2
THOC5 THO complex 5
TIAM1 T-cell lymphoma invasion and metastasis 1
TMCC1 transmembrane and coiled-coil domain family 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRIM25 tripartite motif containing 25
TSSK2 testis-specific serine kinase 2
TTLL1 tubulin tyrosine ligase-like family member 1
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF639 zinc finger protein 639
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACVR2B activin A receptor, type IIB
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCY6 adenylate cyclase 6
AEN apoptosis enhancing nuclease
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOLD1 apolipoprotein L domain containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMC7 armadillo repeat containing 7
BCAR3 breast cancer anti-estrogen resistance 3
BCAS4 breast carcinoma amplified sequence 4
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF30 chromosome 11 open reading frame 30
C19ORF40 chromosome 19 open reading frame 40
C1S complement component 1, s subcomponent
CA11 carbonic anhydrase XI
CAPN15 calpain 15
CCDC85C coiled-coil domain containing 85C
CENPO centromere protein O
CENPT centromere protein T
CGREF1 cell growth regulator with EF-hand domain 1
CLDN14 claudin 14
CNGB3 cyclic nucleotide gated channel beta 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CRELD1 cysteine-rich with EGF-like domains 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DLK1 delta-like 1 homolog (Drosophila)
DLK2 delta-like 2 homolog (Drosophila)
DOCK1 dedicator of cytokinesis 1
DOLPP1 dolichyldiphosphatase 1
EPPK1 epiplakin 1
ETNK2 ethanolamine kinase 2
FBXL15 F-box and leucine-rich repeat protein 15
FGF13 fibroblast growth factor 13
GAB2 GRB2-associated binding protein 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HDAC4 histone deacetylase 4
HIST1H1D histone cluster 1, H1d
HIST1H3G histone cluster 1, H3g
HIST1H4D histone cluster 1, H4d
HOXB5 homeobox B5
HOXC13 homeobox C13
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
KIAA0319L KIAA0319-like
KLF13 Kruppel-like factor 13
KLHL28 kelch-like family member 28
LINC00341 long intergenic non-protein coding RNA 341
LYPD1 LY6/PLAUR domain containing 1
MANSC1 MANSC domain containing 1
MAP9 microtubule-associated protein 9
MCM9 minichromosome maintenance complex component 9
MMP9 matrix metallopeptidase 9
MN1 meningioma (disrupted in balanced translocation) 1
MRPL44 mitochondrial ribosomal protein L44
MRPS34 mitochondrial ribosomal protein S34
NME5 NME/NM23 family member 5
ODF2 outer dense fiber of sperm tails 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP16 poly (ADP-ribose) polymerase family, member 16
PEG3 paternally expressed 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLAC1 placenta-specific 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRICKLE3 prickle homolog 3 (Drosophila)
PTPRE protein tyrosine phosphatase, receptor type, E
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RHOBTB2 Rho-related BTB domain containing 2
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SETD1B SET domain containing 1B
SLC12A9 solute carrier family 12, member 9
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
STAR steroidogenic acute regulatory protein
STARD13 StAR-related lipid transfer (START) domain containing 13
SUGCT succinyl-CoA:glutarate-CoA transferase
SYNPO synaptopodin
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAGLN3 transgelin 3
TMEM209 transmembrane protein 209
TMEM8B transmembrane protein 8B
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRIM66 tripartite motif containing 66
USB1 U6 snRNA biogenesis 1
USP6 ubiquitin specific peptidase 6
YY2 YY2 transcription factor
ZC3H12A zinc finger CCCH-type containing 12A
ZNF230 zinc finger protein 230
ZNF273 zinc finger protein 273
ZNF37BP zinc finger protein 37B, pseudogene
ZNF629 zinc finger protein 629
ZNF767P zinc finger family member 767, pseudogene