ribavirin-6521 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the ribavirin-6521 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ADAM7 ADAM metallopeptidase domain 7
ARTN artemin
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BNC2 basonuclin 2
BTF3P11 basic transcription factor 3 pseudogene 11
BTN2A2 butyrophilin, subfamily 2, member A2
C21ORF2 chromosome 21 open reading frame 2
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CALB2 calbindin 2
CAPN9 calpain 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEMIP cell migration inducing protein, hyaluronan binding
CEP250 centrosomal protein 250kDa
CLEC10A C-type lectin domain family 10, member A
CLIP2 CAP-GLY domain containing linker protein 2
COL1A1 collagen, type I, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRHR2 corticotropin releasing hormone receptor 2
CRIP1 cysteine-rich protein 1 (intestinal)
CXCR2 chemokine (C-X-C motif) receptor 2
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DCC DCC netrin 1 receptor
DCLK2 doublecortin-like kinase 2
EDA ectodysplasin A
EFNB3 ephrin-B3
EGR3 early growth response 3
EPHB2 EPH receptor B2
FAM46C family with sequence similarity 46, member C
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXH1 forkhead box H1
GEM GTP binding protein overexpressed in skeletal muscle
GFI1 growth factor independent 1 transcription repressor
GJB1 gap junction protein, beta 1, 32kDa
GPR68 G protein-coupled receptor 68
GRB10 growth factor receptor-bound protein 10
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HGD homogentisate 1,2-dioxygenase
HIST1H1T histone cluster 1, H1t
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMG20B high mobility group 20B
HOXA7 homeobox A7
HRH2 histamine receptor H2
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGHMBP2 immunoglobulin mu binding protein 2
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ISG20 interferon stimulated exonuclease gene 20kDa
JAK2 Janus kinase 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLHL22 kelch-like family member 22
KRT12 keratin 12, type I
LIN7A lin-7 homolog A (C. elegans)
LRRC48 leucine rich repeat containing 48
MAPK8 mitogen-activated protein kinase 8
MECOM MDS1 and EVI1 complex locus
MOCS1 molybdenum cofactor synthesis 1
NRAP nebulin-related anchoring protein
PALM paralemmin
PDE11A phosphodiesterase 11A
PTRF polymerase I and transcript release factor
QPCTL glutaminyl-peptide cyclotransferase-like
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGK1 serum/glucocorticoid regulated kinase 1
SIPA1 signal-induced proliferation-associated 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SND1-IT1 SND1 intronic transcript 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPON1 spondin 1, extracellular matrix protein
TCF20 transcription factor 20 (AR1)
THY1 Thy-1 cell surface antigen
TMEM212 transmembrane protein 212
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNS2 tensin 2
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
UTRN utrophin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WIPF1 WAS/WASL interacting protein family, member 1
WNT6 wingless-type MMTV integration site family, member 6
ZBTB39 zinc finger and BTB domain containing 39
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF112 zinc finger protein 112
ZNF318 zinc finger protein 318
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACSF2 acyl-CoA synthetase family member 2
ADCY6 adenylate cyclase 6
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P3 annexin A2 pseudogene 3
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BCAS1 breast carcinoma amplified sequence 1
BIRC7 baculoviral IAP repeat containing 7
C11ORF30 chromosome 11 open reading frame 30
C1ORF105 chromosome 1 open reading frame 105
C2ORF27A chromosome 2 open reading frame 27A
C8ORF60 chromosome 8 open reading frame 60
C9ORF9 chromosome 9 open reading frame 9
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDK20 cyclin-dependent kinase 20
CDKL3 cyclin-dependent kinase-like 3
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CST6 cystatin E/M
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
EFCAB2 EF-hand calcium binding domain 2
ENO2 enolase 2 (gamma, neuronal)
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO22 F-box protein 22
FBXO31 F-box protein 31
FGD6 FYVE, RhoGEF and PH domain containing 6
FOXN2 forkhead box N2
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
GALK1 galactokinase 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1E histone cluster 1, H1e
HIST1H4A histone cluster 1, H4a
HIST1H4F histone cluster 1, H4f
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
ITPKB inositol-trisphosphate 3-kinase B
KCTD7 potassium channel tetramerization domain containing 7
KIAA0753 KIAA0753
KIAA1456 KIAA1456
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
LAMP3 lysosomal-associated membrane protein 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LRRC61 leucine rich repeat containing 61
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAST3 microtubule associated serine/threonine kinase 3
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEIS1 Meis homeobox 1
MON1B MON1 secretory trafficking family member B
NLGN1 neuroligin 1
NOL12 nucleolar protein 12
NUAK1 NUAK family, SNF1-like kinase, 1
ONECUT2 one cut homeobox 2
PAIP2B poly(A) binding protein interacting protein 2B
PER3 period circadian clock 3
PROS1 protein S (alpha)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF25 ring finger protein 25
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCAI suppressor of cancer cell invasion
SH2D4A SH2 domain containing 4A
SKA1 spindle and kinetochore associated complex subunit 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STIM1 stromal interaction molecule 1
SYNC syncoilin, intermediate filament protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TARP TCR gamma alternate reading frame protein
TCHH trichohyalin
THOP1 thimet oligopeptidase 1
TMEM120B transmembrane protein 120B
TMEM57 transmembrane protein 57
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VEGFC vascular endothelial growth factor C
WDR19 WD repeat domain 19
WDR7 WD repeat domain 7
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF446 zinc finger protein 446
ZNF492 zinc finger protein 492
ZNF516 zinc finger protein 516
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747
ZNF750 zinc finger protein 750
ZNF768 zinc finger protein 768