rho guanyl-nucleotide exchange factor activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. (Gene Ontology, GO_0005089)
External Link http://amigo.geneontology.org/amigo/term/GO:0005089
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Genes

76 genes performing the rho guanyl-nucleotide exchange factor activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ABR active BCR-related
AKAP13 A kinase (PRKA) anchor protein 13
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ALS2CL ALS2 C-terminal like
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARHGEF39 Rho guanine nucleotide exchange factor (GEF) 39
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
BCR breakpoint cluster region
DNMBP dynamin binding protein
DOCK10 dedicator of cytokinesis 10
DOCK11 dedicator of cytokinesis 11
DOCK2 dedicator of cytokinesis 2
DOCK9 dedicator of cytokinesis 9
ECT2 epithelial cell transforming 2
ECT2L epithelial cell transforming 2 like
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FGD5 FYVE, RhoGEF and PH domain containing 5
FGD6 FYVE, RhoGEF and PH domain containing 6
ITSN1 intersectin 1 (SH3 domain protein)
ITSN2 intersectin 2
KALRN kalirin, RhoGEF kinase
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MCF2L2 MCF.2 cell line derived transforming sequence-like 2
NET1 neuroepithelial cell transforming 1
NGEF neuronal guanine nucleotide exchange factor
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SPATA13 spermatogenesis associated 13
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TRIO trio Rho guanine nucleotide exchange factor
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor