rheumatoid arthritis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint. (Human Disease Ontology, DOID_7148)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003561
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Genes

6 gene mutations causing the rheumatoid arthritis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IL1RN interleukin 1 receptor antagonist
IL6ST interleukin 6 signal transducer
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
TNF tumor necrosis factor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa