rheumatoid arthritis Gene Set

Dataset DISEASES Curated Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint. (Human Disease Ontology, DOID_7148)
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Genes

58 genes involed in the disease rheumatoid arthritis from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

Symbol Name
AFF3 AF4/FMR2 family, member 3
ARID5B AT rich interactive domain 5B (MRF1-like)
BLK BLK proto-oncogene, Src family tyrosine kinase
C5 complement component 5
CCL21 chemokine (C-C motif) ligand 21
CCR6 chemokine (C-C motif) receptor 6
CD2 CD2 molecule
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD5 CD5 molecule
CD58 CD58 molecule
CTLA4 cytotoxic T-lymphocyte-associated protein 4
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GATA3 GATA binding protein 3
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL2 interleukin 2
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IRAK1 interleukin-1 receptor-associated kinase 1
IRF5 interferon regulatory factor 5
IRF8 interferon regulatory factor 8
KIF5A kinesin family member 5A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
PADI4 peptidyl arginine deiminase, type IV
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
POU3F1 POU class 3 homeobox 1
PRDM1 PR domain containing 1, with ZNF domain
PRKCQ protein kinase C, theta
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PXK PX domain containing serine/threonine kinase
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RCAN1 regulator of calcineurin 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RUNX1 runt-related transcription factor 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SPRED2 sprouty-related, EVH1 domain containing 2
STAT4 signal transducer and activator of transcription 4
TAGAP T-cell activation RhoGTPase activating protein
TLE3 transducin-like enhancer of split 3
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRAF1 TNF receptor-associated factor 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TYK2 tyrosine kinase 2
WISP3 WNT1 inducible signaling pathway protein 3