rheumatoid arthritis disease specific synovial fibroblast Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Rheumatoid arthritis synovial fibroblasts constitute a quite unique cell type that distinguishes rheumatoid arthritis from other inflammatory conditions of the joints. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004914)
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Genes

142 proteins co-occuring with the tissue rheumatoid arthritis disease specific synovial fibroblast in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
PMFBP1 polyamine modulated factor 1 binding protein 1 1.45983
MMP1 matrix metallopeptidase 1 1.36587
MMP3 matrix metallopeptidase 3 1.29444
IL1B interleukin 1, beta 1.2904
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.1829
TNF tumor necrosis factor 1.12084
TADA1 transcriptional adaptor 1 1.04225
WDFY3 WD repeat and FYVE domain containing 3 1.02951
SUMO1 small ubiquitin-like modifier 1 0.935341
CXCL16 chemokine (C-X-C motif) ligand 16 0.913507
CCR6 chemokine (C-C motif) receptor 6 0.912226
IL17A interleukin 17A 0.903701
IL18 interleukin 18 0.88671
CXCR6 chemokine (C-X-C motif) receptor 6 0.869373
TLR4 toll-like receptor 4 0.848745
TLR2 toll-like receptor 2 0.831129
CD4 CD4 molecule 0.829034
MMP13 matrix metallopeptidase 13 0.817322
CCL2 chemokine (C-C motif) ligand 2 0.812726
IL1RN interleukin 1 receptor antagonist 0.803544
FBXO3 F-box protein 3 0.788131
IL22RA1 interleukin 22 receptor, alpha 1 0.744214
IL2RA interleukin 2 receptor, alpha 0.703127
TLR3 toll-like receptor 3 0.700262
CD68 CD68 molecule 0.656242
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.650154
JUN jun proto-oncogene 0.642858
IL18BP interleukin 18 binding protein 0.634762
TTC34 tetratricopeptide repeat domain 34 0.621428
CXCR3 chemokine (C-X-C motif) receptor 3 0.621428
CAPN8 calpain 8 0.619007
IL2 interleukin 2 0.616586
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.614571
CCL3 chemokine (C-C motif) ligand 3 0.611346
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.608527
CXCL5 chemokine (C-X-C motif) ligand 5 0.603697
SH3RF1 SH3 domain containing ring finger 1 0.600881
SENP1 SUMO1/sentrin specific peptidase 1 0.59646
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.588031
CD44 CD44 molecule (Indian blood group) 0.585224
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.582019
COMP cartilage oligomeric matrix protein 0.569222
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.561644
PHB2 prohibitin 2 0.557661
CCRL2 chemokine (C-C motif) receptor-like 2 0.555671
IL16 interleukin 16 0.552888
FLT3LG fms-related tyrosine kinase 3 ligand 0.55249
PRELP proline/arginine-rich end leucine-rich repeat protein 0.550106
MAPK13 mitogen-activated protein kinase 13 0.543756
VCAM1 vascular cell adhesion molecule 1 0.540585
IL23A interleukin 23, alpha subunit p19 0.540188
IL33 interleukin 33 0.534647
TREX1 three prime repair exonuclease 1 0.530298
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.525166
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.521617
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.519647
MIR146A microRNA 146a 0.518859
CRP C-reactive protein, pentraxin-related 0.517284
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 0.51335
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.510992
PLA2G1B phospholipase A2, group IB (pancreas) 0.510206
IL17RA interleukin 17 receptor A 0.478145
S100A4 S100 calcium binding protein A4 0.476589
IL6 interleukin 6 0.473092
ANXA5 annexin A5 0.452969
CHAD chondroadherin 0.446807
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.446038
PTGES prostaglandin E synthase 0.444499
CCDC34 coiled-coil domain containing 34 0.437972
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.437589
C1QA complement component 1, q subcomponent, A chain 0.43146
CCL20 chemokine (C-C motif) ligand 20 0.424581
MMP2 matrix metallopeptidase 2 0.423054
MMP9 matrix metallopeptidase 9 0.413151
CDSN corneodesmosin 0.401007
TRAF3 TNF receptor-associated factor 3 0.40025
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.398357
TIMP1 TIMP metallopeptidase inhibitor 1 0.395331
CXCL12 chemokine (C-X-C motif) ligand 12 0.388912
ICAM1 intercellular adhesion molecule 1 0.388535
ADIPOR2 adiponectin receptor 2 0.38665
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.38552
SMS spermine synthase 0.383637
IRF3 interferon regulatory factor 3 0.38326
CD163 CD163 molecule 0.379123
IRAK4 interleukin-1 receptor-associated kinase 4 0.374993
PADI2 peptidyl arginine deiminase, type II 0.369747
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.364886
TGFB1 transforming growth factor, beta 1 0.363393
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.359292
CD40 CD40 molecule, TNF receptor superfamily member 5 0.356314
C5AR1 complement component 5a receptor 1 0.35334
ADIPOR1 adiponectin receptor 1 0.348889
IFNL1 interferon, lambda 1 0.346668
ADAM10 ADAM metallopeptidase domain 10 0.344449
IL10RA interleukin 10 receptor, alpha 0.33156
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.32497
PSAT1 phosphoserine aminotransferase 1 0.320227
DYNLRB1 dynein, light chain, roadblock-type 1 0.317679
CLEC1B C-type lectin domain family 1, member B 0.315135
CD80 CD80 molecule 0.313683
CXCL10 chemokine (C-X-C motif) ligand 10 0.310059
HIST1H1B histone cluster 1, H1b 0.309335
RIPK2 receptor-interacting serine-threonine kinase 2 0.309335
C5 complement component 5 0.308251
CXCL11 chemokine (C-X-C motif) ligand 11 0.306444
SUMO3 small ubiquitin-like modifier 3 0.303198
ICOSLG inducible T-cell co-stimulator ligand 0.29996
DDR2 discoidin domain receptor tyrosine kinase 2 0.298165
HYAL2 hyaluronoglucosaminidase 2 0.29673
BMX BMX non-receptor tyrosine kinase 0.29673
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.294939
CD69 CD69 molecule 0.294939
A2M alpha-2-macroglobulin 0.294223
S100A8 S100 calcium binding protein A8 0.293866
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.289226
MAPK9 mitogen-activated protein kinase 9 0.287447
HDAC9 histone deacetylase 9 0.286381
IL5 interleukin 5 0.286026
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.283899
SUMO2 small ubiquitin-like modifier 2 0.277197
CCR1 chemokine (C-C motif) receptor 1 0.270561
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.269867
CD200R1 CD200 receptor 1 0.257572
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.257572
S100A9 S100 calcium binding protein A9 0.252261
COPS5 COP9 signalosome subunit 5 0.251279
SIRT6 sirtuin 6 0.250953
ADGRE5 adhesion G protein-coupled receptor E5 0.246124
CD40LG CD40 ligand 0.23961
HDAC11 histone deacetylase 11 0.230382
MST1 macrophage stimulating 1 0.229568
IGFBP7 insulin-like growth factor binding protein 7 0.229032
MAPK11 mitogen-activated protein kinase 11 0.226667
IL13 interleukin 13 0.223662
CCL13 chemokine (C-C motif) ligand 13 0.222938
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.222224
TLR9 toll-like receptor 9 0.220831
TP53 tumor protein p53 0.219707
CXCL8 chemokine (C-X-C motif) ligand 8 0.218613
BTK Bruton agammaglobulinemia tyrosine kinase 0.218613
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.214954