rheumatoid arthritis disease specific fibroblast-like synoviocyte Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Fibroblast-like synoviocyte (FLS) cultured from rheumatoid arthritis (RA) synovial tissues. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003703)
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Genes

150 proteins co-occuring with the tissue rheumatoid arthritis disease specific fibroblast-like synoviocyte in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
MMP3 matrix metallopeptidase 3 1.49161
MMP1 matrix metallopeptidase 1 1.39146
IL1B interleukin 1, beta 1.37545
MIR346 microRNA 346 1.21935
TNF tumor necrosis factor 1.07794
IL17RC interleukin 17 receptor C 1.01593
IL32 interleukin 32 0.981953
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.981518
MMP13 matrix metallopeptidase 13 0.95384
DYNLRB1 dynein, light chain, roadblock-type 1 0.916496
MMP9 matrix metallopeptidase 9 0.907961
TLR3 toll-like receptor 3 0.89477
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.88671
PHOSPHO2 phosphatase, orphan 2 0.876129
CCL2 chemokine (C-C motif) ligand 2 0.870217
KIAA1524 KIAA1524 0.850425
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.842027
TLR2 toll-like receptor 2 0.841608
JUN jun proto-oncogene 0.837414
TADA1 transcriptional adaptor 1 0.819412
IL6 interleukin 6 0.818576
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.816486
BAIAP2L1 BAI1-associated protein 2-like 1 0.803961
PDCD5 programmed cell death 5 0.791877
WISP3 WNT1 inducible signaling pathway protein 3 0.786468
MGARP mitochondria-localized glutamic acid-rich protein 0.783557
TRIM2 tripartite motif containing 2 0.781478
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.767783
MTX3 metaxin 3 0.75247
TLR4 toll-like receptor 4 0.752057
IL22RA1 interleukin 22 receptor, alpha 1 0.742564
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.7335
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.719934
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.713779
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.704355
MMP2 matrix metallopeptidase 2 0.701899
IL17A interleukin 17A 0.699035
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.693719
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.672913
ADGRG2 adhesion G protein-coupled receptor G2 0.66071
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.652589
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.651777
BAX BCL2-associated X protein 0.648938
MAB21L2 mab-21-like 2 (C. elegans) 0.644884
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.642454
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 0.642454
CYR61 cysteine-rich, angiogenic inducer, 61 0.630314
CCL7 chemokine (C-C motif) ligand 7 0.628293
TP53 tumor protein p53 0.617393
TIMP1 TIMP metallopeptidase inhibitor 1 0.600479
CXCL10 chemokine (C-X-C motif) ligand 10 0.588431
PARP1 poly (ADP-ribose) polymerase 1 0.584422
MAPK8 mitogen-activated protein kinase 8 0.584022
IRAK4 interleukin-1 receptor-associated kinase 4 0.582019
JAK2 Janus kinase 2 0.574816
ACPP acid phosphatase, prostate 0.573217
ANXA5 annexin A5 0.56284
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.55408
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.55249
IL34 interleukin 34 0.541377
TNIP1 TNFAIP3 interacting protein 1 0.536625
MAP2K7 mitogen-activated protein kinase kinase 7 0.53267
MTX1 metaxin 1 0.527534
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.525955
VIP vasoactive intestinal peptide 0.51571
UBE2I ubiquitin-conjugating enzyme E2I 0.510599
CXCL8 chemokine (C-X-C motif) ligand 8 0.50275
IL17RB interleukin 17 receptor B 0.499615
GDF10 growth differentiation factor 10 0.497657
LPAR1 lysophosphatidic acid receptor 1 0.496874
IL17RA interleukin 17 receptor A 0.493745
CLEC12A C-type lectin domain family 12, member A 0.491009
AICDA activation-induced cytidine deaminase 0.490619
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.484376
SPRED1 sprouty-related, EVH1 domain containing 1 0.482817
DLL3 delta-like 3 (Drosophila) 0.482428
ANXA1 annexin A1 0.471151
SNX9 sorting nexin 9 0.469987
SAA1 serum amyloid A1 0.464561
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.461852
MAPT microtubule-associated protein tau 0.461465
BID BH3 interacting domain death agonist 0.455284
BSG basigin (Ok blood group) 0.454126
SAA4 serum amyloid A4, constitutive 0.444115
CALCRL calcitonin receptor-like 0.437972
MIR19A microRNA 19a 0.436822
POU3F3 POU class 3 homeobox 3 0.433374
SENP1 SUMO1/sentrin specific peptidase 1 0.429547
MDM4 MDM4, p53 regulator 0.428018
FAS Fas cell surface death receptor 0.428018
TYMP thymidine phosphorylase 0.42649
CNR2 cannabinoid receptor 2 (macrophage) 0.424581
EFNA3 ephrin-A3 0.408212
CTSK cathepsin K 0.399871
FPR2 formyl peptide receptor 2 0.394953
MIR22 microRNA 22 0.393064
LGALS8 lectin, galactoside-binding, soluble, 8 0.390799
CCL8 chemokine (C-C motif) ligand 8 0.390421
FZD5 frizzled class receptor 5 0.377996
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.370121
HOXD10 homeobox D10 0.369373
EZR ezrin 0.368624
HOXD11 homeobox D11 0.364139
SFRP5 secreted frizzled-related protein 5 0.363766
CALCR calcitonin receptor 0.36302
IFNL1 interferon, lambda 1 0.361527
IL27RA interleukin 27 receptor, alpha 0.351856
EGLN2 egl-9 family hypoxia-inducible factor 2 0.350001
CD40 CD40 molecule, TNF receptor superfamily member 5 0.34963
HAPLN1 hyaluronan and proteoglycan link protein 1 0.337808
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.329361
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.326067
MAPK9 mitogen-activated protein kinase 9 0.317679
TRAF2 TNF receptor-associated factor 2 0.31187
WNT1 wingless-type MMTV integration site family, member 1 0.311507
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.307889
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.303198
ICAM1 intercellular adhesion molecule 1 0.302838
CLU clusterin 0.298524
RGMB repulsive guidance molecule family member b 0.294939
ADM adrenomedullin 0.293866
CCL5 chemokine (C-C motif) ligand 5 0.293508
S100A8 S100 calcium binding protein A8 0.292436
POSTN periostin, osteoblast specific factor 0.281776
VEGFA vascular endothelial growth factor A 0.281776
IRAK3 interleukin-1 receptor-associated kinase 3 0.281423
PARG poly (ADP-ribose) glycohydrolase 0.274394
EGLN3 egl-9 family hypoxia-inducible factor 3 0.268482
SFRP4 secreted frizzled-related protein 4 0.267446
COPS5 COP9 signalosome subunit 5 0.264696
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.262304
UCN3 urocortin 3 0.261964
ADGRE5 adhesion G protein-coupled receptor E5 0.259254
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.25457
IL15 interleukin 15 0.24804
LPAR2 lysophosphatidic acid receptor 2 0.247399
BTK Bruton agammaglobulinemia tyrosine kinase 0.241132
VCAM1 vascular cell adhesion molecule 1 0.237216
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.232039
CCR6 chemokine (C-C motif) receptor 6 0.231482
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.229839
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.228234
LHX2 LIM homeobox 2 0.226667
HOXD13 homeobox D13 0.225647
MYD88 myeloid differentiation primary response 88 0.223906
RFC2 replication factor C (activator 1) 2, 40kDa 0.223662
GLS glutaminase 0.221989
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.215928
AGER advanced glycosylation end product-specific receptor 0.213112
FGF5 fibroblast growth factor 5 0.212936