retinal pigment epithelium atrophy Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description acquired diminution of the size of the epithelial layer of the retina composed of cells containing pigment granules, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes (Mammalian Phenotype Ontology, MP_0005548)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005548
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Genes

5 gene mutations causing the retinal pigment epithelium atrophy phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
BMP7 bone morphogenetic protein 7
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FAT1 FAT atypical cadherin 1
MERTK MER proto-oncogene, tyrosine kinase