responsive Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

305 genes co-occuring with the biological term responsive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ABRA actin binding Rho activating protein
ACE angiotensin I converting enzyme
ACVR1 activin A receptor, type I
ADCY7 adenylate cyclase 7
ADM adrenomedullin
AHSP alpha hemoglobin stabilizing protein
AKAP5 A kinase (PRKA) anchor protein 5
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5 arachidonate 5-lipoxygenase
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA5 apolipoprotein A-V
APOC2 apolipoprotein C-II
AR androgen receptor
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATF3 activating transcription factor 3
ATP13A2 ATPase type 13A2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN2 ataxin 2
ATXN3 ataxin 3
B3GAT1 beta-1,3-glucuronyltransferase 1
BACE2 beta-site APP-cleaving enzyme 2
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAD BCL2-associated agonist of cell death
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
CA2 carbonic anhydrase II
CACNG2 calcium channel, voltage-dependent, gamma subunit 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMTA1 calmodulin binding transcription activator 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCND1 cyclin D1
CCNE1 cyclin E1
CCR3 chemokine (C-C motif) receptor 3
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIRH1A cirrhosis, autosomal recessive 1A (cirhin)
CLCA1 chloride channel accessory 1
CLEC2B C-type lectin domain family 2, member B
COL10A1 collagen, type X, alpha 1
COL1A2 collagen, type I, alpha 2
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CPT1A carnitine palmitoyltransferase 1A (liver)
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CRHR1 corticotropin releasing hormone receptor 1
CSF1R colony stimulating factor 1 receptor
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CST3 cystatin C
CTBP1 C-terminal binding protein 1
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSS cathepsin S
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYGB cytoglobin
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYR61 cysteine-rich, angiogenic inducer, 61
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDIT3 DNA-damage-inducible transcript 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DRD2 dopamine receptor D2
DST dystonin
E2F1 E2F transcription factor 1
EDA ectodysplasin A
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EGR2 early growth response 2
EIF4E eukaryotic translation initiation factor 4E
ELF5 E74-like factor 5 (ets domain transcription factor)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
FBXO7 F-box protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF2 fibroblast growth factor 2 (basic)
FGG fibrinogen gamma chain
FIP1L1 factor interacting with PAPOLA and CPSF1
FLT3LG fms-related tyrosine kinase 3 ligand
FZD1 frizzled class receptor 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GADD45B growth arrest and DNA-damage-inducible, beta
GCH1 GTP cyclohydrolase 1
GCK glucokinase (hexokinase 4)
GHR growth hormone receptor
GHSR growth hormone secretagogue receptor
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS3 GINS complex subunit 3 (Psf3 homolog)
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNMT glycine N-methyltransferase
GRK4 G protein-coupled receptor kinase 4
GSK3B glycogen synthase kinase 3 beta
HAMP hepcidin antimicrobial peptide
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF3A hypoxia inducible factor 3, alpha subunit
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HPSE heparanase
HPX hemopexin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ICAM1 intercellular adhesion molecule 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL12A interleukin 12A
IL13 interleukin 13
IL1B interleukin 1, beta
IL20 interleukin 20
IL6 interleukin 6
INS insulin
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
IWS1 IWS1 homolog (S. cerevisiae)
JUN jun proto-oncogene
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK4 potassium channel, two pore domain subfamily K, member 4
KDM4B lysine (K)-specific demethylase 4B
KL klotho
KLF4 Kruppel-like factor 4 (gut)
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LRRC3DN LRRC3 downstream neighbor (non-protein coding)
LTF lactotransferrin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MDFIC MyoD family inhibitor domain containing
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR126 microRNA 126
MIR149 microRNA 149
MIR181A2 microRNA 181a-2
MIR222 microRNA 222
MIR223 microRNA 223
MIR30C2 microRNA 30c-2
MKI67 marker of proliferation Ki-67
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP2 matrix metallopeptidase 2
MRGPRX2 MAS-related GPR, member X2
MSX2 msh homeobox 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC17 mucin 17, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAGS N-acetylglutamate synthase
NCOA1 nuclear receptor coactivator 1
NDRG2 NDRG family member 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFYA nuclear transcription factor Y, alpha
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH1 notch 1
NPTX1 neuronal pentraxin I
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NXNL1 nucleoredoxin-like 1
NXNL2 nucleoredoxin-like 2
OPRM1 opioid receptor, mu 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAX8 paired box 8
PAXBP1 PAX3 and PAX7 binding protein 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PECAM1 platelet/endothelial cell adhesion molecule 1
PGF placental growth factor
PGR progesterone receptor
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLK2 polo-like kinase 2
PMEPA1 prostate transmembrane protein, androgen induced 1
POU2F1 POU class 2 homeobox 1
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCQ protein kinase C, theta
PRLR prolactin receptor
PROS1 protein S (alpha)
PRTN3 proteinase 3
PTEN phosphatase and tensin homolog
PTHLH parathyroid hormone-like hormone
RASGRP4 RAS guanyl releasing protein 4
RCAN1 regulator of calcineurin 1
REN renin
REST RE1-silencing transcription factor
RUNX2 runt-related transcription factor 2
RWDD2B RWD domain containing 2B
RXRA retinoid X receptor, alpha
SAT1 spermidine/spermine N1-acetyltransferase 1
SCARB1 scavenger receptor class B, member 1
SDC1 syndecan 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERBP1 SERPINE1 mRNA binding protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHH sonic hedgehog
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAI2 snail family zinc finger 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX2 SRY (sex determining region Y)-box 2
SP1 Sp1 transcription factor
SPG11 spastic paraplegia 11 (autosomal recessive)
SPP1 secreted phosphoprotein 1
SREBF1 sterol regulatory element binding transcription factor 1
SSRP1 structure specific recognition protein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK10 serine/threonine kinase 10
STK11 serine/threonine kinase 11
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TGFB1 transforming growth factor, beta 1
THRA thyroid hormone receptor, alpha
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLL1 tolloid-like 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNIP1 TNFAIP3 interacting protein 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
TRAF3IP2 TRAF3 interacting protein 2
TRIB3 tribbles pseudokinase 3
TSPYL2 TSPY-like 2
TXNRD1 thioredoxin reductase 1
UBE3A ubiquitin protein ligase E3A
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIPR2 vasoactive intestinal peptide receptor 2
VWF von Willebrand factor
WNT4 wingless-type MMTV integration site family, member 4
WT1 Wilms tumor 1
XAF1 XIAP associated factor 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa