response to radiation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. (Gene Ontology, GO_0009314)
External Link http://amigo.geneontology.org/amigo/term/GO:0009314
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Genes

442 genes participating in the response to radiation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTR5 ARP5 actin-related protein 5 homolog (yeast)
ADAM2 ADAM metallopeptidase domain 2
ADIRF adipogenesis regulatory factor
ADRA1B adrenoceptor alpha 1B
AEN apoptosis enhancing nuclease
AGRN agrin
AGRP agouti related neuropeptide
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT2 angiopoietin 2
ANXA1 annexin A1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOB apolipoprotein B
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOC2 apolipoprotein C-II
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
ARRB1 arrestin, beta 1
ASIC2 acid sensing (proton gated) ion channel 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATM ATM serine/threonine kinase
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
ATR ATR serine/threonine kinase
ATXN1 ataxin 1
AURKB aurora kinase B
BABAM1 BRISC and BRCA1 A complex member 1
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL3 B-cell CLL/lymphoma 3
BCO1 beta-carotene oxygenase 1
BCO2 beta-carotene oxygenase 2
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BHLHE40 basic helix-loop-helix family, member e40
BLM Bloom syndrome, RecQ helicase-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAT1 BRCA1-associated ATM activator 1
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BRSK1 BR serine/threonine kinase 1
C10ORF90 chromosome 10 open reading frame 90
CABP4 calcium binding protein 4
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCAR2 cell cycle and apoptosis regulator 2
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL7 chemokine (C-C motif) ligand 7
CCND1 cyclin D1
CCR4 chemokine (C-C motif) receptor 4
CDC25A cell division cycle 25A
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CERS1 ceramide synthase 1
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIRBP cold inducible RNA binding protein
CLK2 CDC-like kinase 2
CLOCK clock circadian regulator
CLPS colipase, pancreatic
CNGA1 cyclic nucleotide gated channel alpha 1
CNGA2 cyclic nucleotide gated channel alpha 2
CNGA3 cyclic nucleotide gated channel alpha 3
CNGA4 cyclic nucleotide gated channel alpha 4
CNGB1 cyclic nucleotide gated channel beta 1
CNGB3 cyclic nucleotide gated channel beta 3
COL3A1 collagen, type III, alpha 1
COPS3 COP9 signalosome subunit 3
CRHR1 corticotropin releasing hormone receptor 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRTC1 CREB regulated transcription coactivator 1
CRY1 cryptochrome circadian clock 1
CRY2 cryptochrome circadian clock 2
CRYAB crystallin, alpha B
CTNS cystinosin, lysosomal cystine transporter
CUL4B cullin 4B
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCDC2 doublecortin domain containing 2
DCLRE1C DNA cross-link repair 1C
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDB1 damage-specific DNA binding protein 1, 127kDa
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIAS DNA damage-induced apoptosis suppressor
DEAF1 DEAF1 transcription factor
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP1 dual specificity phosphatase 1
DYNLRB1 dynein, light chain, roadblock-type 1
ECT2 epithelial cell transforming 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELANE elastase, neutrophil expressed
ELK1 ELK1, member of ETS oncogene family
ELOVL4 ELOVL fatty acid elongase 4
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC4 excision repair cross-complementation group 4
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
ERCC8 excision repair cross-complementation group 8
EYA1 EYA transcriptional coactivator and phosphatase 1
EYA3 EYA transcriptional coactivator and phosphatase 3
EYS eyes shut homolog (Drosophila)
F11R F11 receptor
FAM175A family with sequence similarity 175, member A
FANCD2 Fanconi anemia, complementation group D2
FANCG Fanconi anemia, complementation group G
FBXL21 F-box and leucine-rich repeat protein 21 (gene/pseudogene)
FBXL3 F-box and leucine-rich repeat protein 3
FECH ferrochelatase
FEN1 flap structure-specific endonuclease 1
FIGNL1 fidgetin-like 1
FKBPL FK506 binding protein like
FNTA farnesyltransferase, CAAX box, alpha
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXB1 forkhead box B1
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA3 GATA binding protein 3
GJA10 gap junction protein, alpha 10, 62kDa
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GPC1 glypican 1
GPC2 glypican 2
GPC3 glypican 3
GPC4 glypican 4
GPC5 glypican 5
GPC6 glypican 6
GPX1 glutathione peroxidase 1
GRB2 growth factor receptor-bound protein 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRK1 G protein-coupled receptor kinase 1
GRM6 glutamate receptor, metabotropic 6
GTF2H5 general transcription factor IIH, polypeptide 5
GUCA1A guanylate cyclase activator 1A (retina)
GUCA1B guanylate cyclase activator 1B (retina)
GUCA1C guanylate cyclase activator 1C
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
GUCY2F guanylate cyclase 2F, retinal
H2AFX H2A histone family, member X
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST3H2A histone cluster 3, H2a
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGN1 high mobility group nucleosome binding domain 1
HOXA1 homeobox A1
HRAS Harvey rat sarcoma viral oncogene homolog
HRH1 histamine receptor H1
HRH2 histamine receptor H2
HSPG2 heparan sulfate proteoglycan 2
HTT huntingtin
HUS1 HUS1 checkpoint homolog (S. pombe)
HYAL1 hyaluronoglucosaminidase 1
HYAL2 hyaluronoglucosaminidase 2
HYAL3 hyaluronoglucosaminidase 3
ICAM1 intercellular adhesion molecule 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IFT20 intraflagellar transport 20
IGF2 insulin-like growth factor 2
IKBIP IKBKB interacting protein
IL12A interleukin 12A
IL12B interleukin 12B
INIP INTS3 and NABP interacting protein
INO80 INO80 complex subunit
INTS3 integrator complex subunit 3
INTS7 integrator complex subunit 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
IVL involucrin
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KIAA0101 KIAA0101
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT13 keratin 13, type I
KRT14 keratin 14, type I
LDLR low density lipoprotein receptor
LIG4 ligase IV, DNA, ATP-dependent
LPL lipoprotein lipase
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
LRP1 low density lipoprotein receptor-related protein 1
LRP2 low density lipoprotein receptor-related protein 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRN4 leucine rich repeat neuronal 4
LZIC leucine zipper and CTNNBIP1 domain containing
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MBD4 methyl-CpG binding domain protein 4
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MEN1 multiple endocrine neoplasia I
METAP1 methionyl aminopeptidase 1
METAP2 methionyl aminopeptidase 2
MFAP4 microfibrillar-associated protein 4
MGMT O-6-methylguanine-DNA methyltransferase
MME membrane metallo-endopeptidase
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTA1 metastasis associated 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
N4BP1 NEDD4 binding protein 1
NABP1 nucleic acid binding protein 1
NABP2 nucleic acid binding protein 2
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEK1 NIMA-related kinase 1
NET1 neuroepithelial cell transforming 1
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NF1 neurofibromin 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NGF nerve growth factor (beta polypeptide)
NHEJ1 nonhomologous end-joining factor 1
NIPBL Nipped-B homolog (Drosophila)
NLGN3 neuroligin 3
NMT1 N-myristoyltransferase 1
NMT2 N-myristoyltransferase 2
NMU neuromedin U
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOX4 NADPH oxidase 4
NPHP1 nephronophthisis 1 (juvenile)
NPHP4 nephronophthisis 4
NPS neuropeptide S
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR2F6 nuclear receptor subfamily 2, group F, member 6
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OGG1 8-oxoguanine DNA glycosylase
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OPN3 opsin 3
OPN4 opsin 4
OPN5 opsin 5
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PBK PDZ binding kinase
PCP2 Purkinje cell protein 2
PDC phosducin
PDE1B phosphodiesterase 1B, calmodulin-dependent
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDE8B phosphodiesterase 8B
PER1 period circadian clock 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLB1 phospholipase B1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PNKP polynucleotide kinase 3'-phosphatase
PNLIP pancreatic lipase
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLH polymerase (DNA directed), eta
PPEF1 protein phosphatase, EF-hand calcium binding domain 1
PPID peptidylprolyl isomerase D
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRIMPOL primase and polymerase (DNA-directed)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCA protein kinase C, alpha
PRKCQ protein kinase C, theta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPH2 peripherin 2 (retinal degeneration, slow)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRK protein tyrosine phosphatase, receptor type, K
RAD1 RAD1 checkpoint DNA exonuclease
RAD18 RAD18 E3 ubiquitin protein ligase
RAD51 RAD51 recombinase
RAD51AP1 RAD51 associated protein 1
RAD54L RAD54-like (S. cerevisiae)
RAD9A RAD9 homolog A (S. pombe)
RBM4 RNA binding motif protein 4
RBM4B RNA binding motif protein 4B
RBP1 retinol binding protein 1, cellular
RBP2 retinol binding protein 2, cellular
RBP3 retinol binding protein 3, interstitial
RBP4 retinol binding protein 4, plasma
RCVRN recoverin
RDH10 retinol dehydrogenase 10 (all-trans)
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RDH13 retinol dehydrogenase 13 (all-trans/9-cis)
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RDH8 retinol dehydrogenase 8 (all-trans)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REV1 REV1, polymerase (DNA directed)
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RFWD3 ring finger and WD repeat domain 3
RGR retinal G protein coupled receptor
RGS14 regulator of G-protein signaling 14
RGS9 regulator of G-protein signaling 9
RGS9BP regulator of G protein signaling 9 binding protein
RHBDD1 rhomboid domain containing 1
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1
RHO rhodopsin
RHOB ras homolog family member B
RIC8A RIC8 guanine nucleotide exchange factor A
RLBP1 retinaldehyde binding protein 1
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RP1 retinitis pigmentosa 1 (autosomal dominant)
RPE65 retinal pigment epithelium-specific protein 65kDa
RRH retinal pigment epithelium-derived rhodopsin homolog
RRM1 ribonucleotide reductase M1
RUVBL2 RuvB-like AAA ATPase 2
SAG S-antigen; retina and pineal gland (arrestin)
SCARA3 scavenger receptor class A, member 3
SCT secretin
SDC1 syndecan 1
SDC2 syndecan 2
SDC3 syndecan 3
SDC4 syndecan 4
SDF4 stromal cell derived factor 4
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SIRT1 sirtuin 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SMC1A structural maintenance of chromosomes 1A
SNAI2 snail family zinc finger 2
SOD2 superoxide dismutase 2, mitochondrial
SPIDR scaffolding protein involved in DNA repair
SPRTN SprT-like N-terminal domain
STAR steroidogenic acute regulatory protein
STK11 serine/threonine kinase 11
STRA6 stimulated by retinoic acid 6
SWI5 SWI5 recombination repair homolog (yeast)
SYNGAP1 synaptic Ras GTPase activating protein 1
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
THBD thrombomodulin
TICRR TOPBP1-interacting checkpoint and replication regulator
TIGAR TP53 induced glycolysis regulatory phosphatase
TIPIN TIMELESS interacting protein
TLK2 tousled-like kinase 2
TMEM109 transmembrane protein 109
TMEM161A transmembrane protein 161A
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIM13 tripartite motif containing 13
TRIM32 tripartite motif containing 32
TROVE2 TROVE domain family, member 2
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TSPYL5 TSPY-like 5
TTR transthyretin
TUB tubby bipartite transcription factor
TULP1 tubby like protein 1
TXN thioredoxin
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE4B ubiquitination factor E4B
UIMC1 ubiquitin interaction motif containing 1
UNC119 unc-119 homolog (C. elegans)
USF1 upstream transcription factor 1
USP1 ubiquitin specific peptidase 1
USP2 ubiquitin specific peptidase 2
USP28 ubiquitin specific peptidase 28
USP47 ubiquitin specific peptidase 47
UVSSA UV-stimulated scaffold protein A
VCAM1 vascular cell adhesion molecule 1
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRRA1 X-ray radiation resistance associated 1
YAP1 Yes-associated protein 1
YY1 YY1 transcription factor
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZRANB3 zinc finger, RAN-binding domain containing 3