response to endoplasmic reticulum stress Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. (Gene Ontology, GO_0034976)
External Link http://amigo.geneontology.org/amigo/term/GO:0034976
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Genes

159 genes participating in the response to endoplasmic reticulum stress biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ACADVL acyl-CoA dehydrogenase, very long chain
ADD1 adducin 1 (alpha)
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ALOX15 arachidonate 15-lipoxygenase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATF6B activating transcription factor 6 beta
ATG10 autophagy related 10
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
BAG6 BCL2-associated athanogene 6
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BHLHA15 basic helix-loop-helix family, member a15
BRSK2 BR serine/threonine kinase 2
CALR calreticulin
CASP12 caspase 12 (gene/pseudogene)
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCDC47 coiled-coil domain containing 47
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CREB3L1 cAMP responsive element binding protein 3-like 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CREB3L3 cAMP responsive element binding protein 3-like 3
CREB3L4 cAMP responsive element binding protein 3-like 4
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTH cystathionine gamma-lyase
CUL7 cullin 7
CXCL8 chemokine (C-X-C motif) ligand 8
CXXC1 CXXC finger protein 1
DAB2IP DAB2 interacting protein
DCTN1 dynactin 1
DDIT3 DNA-damage-inducible transcript 3
DDRGK1 DDRGK domain containing 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DERL1 derlin 1
DERL2 derlin 2
DERL3 derlin 3
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1L ERO1-like (S. cerevisiae)
ERP27 endoplasmic reticulum protein 27
ERP44 endoplasmic reticulum protein 44
EXTL3 exostosin-like glycosyltransferase 3
FAM129A family with sequence similarity 129, member A
FKBP14 FK506 binding protein 14, 22 kDa
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GOSR2 golgi SNAP receptor complex member 2
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HDGF hepatoma-derived growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
IFNG interferon, gamma
IGFBP1 insulin-like growth factor binding protein 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUN jun proto-oncogene
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KLHDC3 kelch domain containing 3
LMNA lamin A/C
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MYDGF myeloid-derived growth factor
NCK1 NCK adaptor protein 1
NFE2L2 nuclear factor, erythroid 2-like 2
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
P4HB prolyl 4-hydroxylase, beta polypeptide
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP16 poly (ADP-ribose) polymerase family, member 16
PDIA2 protein disulfide isomerase family A, member 2
PDIA3 protein disulfide isomerase family A, member 3
PDIA4 protein disulfide isomerase family A, member 4
PDIA5 protein disulfide isomerase family A, member 5
PDIA6 protein disulfide isomerase family A, member 6
PDILT protein disulfide isomerase-like, testis expressed
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PML promyelocytic leukemia
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PREB prolactin regulatory element binding
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RNF121 ring finger protein 121
RNF175 ring finger protein 175
SCAMP5 secretory carrier membrane protein 5
SDF2L1 stromal cell-derived factor 2-like 1
SEC31A SEC31 homolog A (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELK selenoprotein K
SERP1 stress-associated endoplasmic reticulum protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SRPR signal recognition particle receptor (docking protein)
SRPRB signal recognition particle receptor, B subunit
SRPX sushi-repeat containing protein, X-linked
SSR1 signal sequence receptor, alpha
STC2 stanniocalcin 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TARDBP TAR DNA binding protein
TATDN2 TatD DNase domain containing 2
TBL2 transducin (beta)-like 2
THBS1 thrombospondin 1
THBS4 thrombospondin 4
TLN1 talin 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMX1 thioredoxin-related transmembrane protein 1
TMX3 thioredoxin-related transmembrane protein 3
TMX4 thioredoxin-related transmembrane protein 4
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TP53 tumor protein p53
TPP1 tripeptidyl peptidase I
TRAF2 TNF receptor-associated factor 2
TRIB3 tribbles pseudokinase 3
TSPYL2 TSPY-like 2
TXNDC11 thioredoxin domain containing 11
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBA5 ubiquitin-like modifier activating enzyme 5
UBE2K ubiquitin-conjugating enzyme E2K
UBQLN1 ubiquilin 1
UFC1 ubiquitin-fold modifier conjugating enzyme 1
UFL1 UFM1-specific ligase 1
UFM1 ubiquitin-fold modifier 1
USP19 ubiquitin specific peptidase 19
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VCP valosin containing protein
VIMP VCP-interacting membrane selenoprotein
WFS1 Wolfram syndrome 1 (wolframin)
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YOD1 YOD1 deubiquitinase
ZBTB17 zinc finger and BTB domain containing 17