respiratory system cancer Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An organ system cancer located_in the respiratory system that is characterized by uncontrolled cellular proliferation in the respiratory tract. (Human Disease Ontology, DOID_0050615)
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Genes

68 genes associated with the disease respiratory system cancer in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HLA-C major histocompatibility complex, class I, C 1.83302
TERT telomerase reverse transcriptase 1.65491
HLA-A major histocompatibility complex, class I, A 1.35663
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.27521
VTI1A vesicle transport through interaction with t-SNAREs 1A 1.26228
MTMR3 myotubularin related protein 3 0.910378
MIPEP mitochondrial intermediate peptidase 0.872896
HLA-J major histocompatibility complex, class I, J (pseudogene) 0.7623
CLPTM1L CLPTM1-like 0.69843
GOPC golgi-associated PDZ and coiled-coil motif containing 0.670996
APOM apolipoprotein M 0.670996
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 0.602429
TP63 tumor protein p63 0.572184
HYKK hydroxylysine kinase 0.52461
MECOM MDS1 and EVI1 complex locus 0.52461
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.52461
XXYLT1 xyloside xylosyltransferase 1 0.486425
TRIM27 tripartite motif containing 27 0.486425
IER3 immediate early response 3 0.486425
ITGA9 integrin, alpha 9 0.4215
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.414708
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.408752
SAXO1 stabilizer of axonemal microtubules 1 0.368757
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.345945
ANKRD7 ankyrin repeat domain 7 0.327313
CMKLR1 chemerin chemokine-like receptor 1 0.311576
RAD52 RAD52 homolog (S. cerevisiae) 0.297866
BLACE B-cell acute lymphoblastic leukemia expressed 0.274608
STAMBPL1 STAM binding protein-like 1 0.256228
PIEZO2 piezo-type mechanosensitive ion channel component 2 0.256228
TGM5 transglutaminase 5 0.256228
ACTA2 actin, alpha 2, smooth muscle, aorta 0.256228
PTH2R parathyroid hormone 2 receptor 0.197766
CDH9 cadherin 9, type 2 (T1-cadherin) 0.197766
ALG10B ALG10B, alpha-1,2-glucosyltransferase 0.197766
WLS wntless Wnt ligand secretion mediator 0.197766
MIER2 mesoderm induction early response 1, family member 2 0.15771
FABP12 fatty acid binding protein 12 0.15771
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.15771
RBMS3 RNA binding motif, single stranded interacting protein 3 0.15771
DSCAM Down syndrome cell adhesion molecule 0.126165
ADGRF3 adhesion G protein-coupled receptor F3 0.126165
SEC14L5 SEC14-like 5 (S. cerevisiae) 0.126165
ADCK1 aarF domain containing kinase 1 0.126165
GKN1 gastrokine 1 0.100789
ZNF28 zinc finger protein 28 0.100789
RIF1 replication timing regulatory factor 1 0.100789
ZNF320 zinc finger protein 320 0.100789
GPC5 glypican 5 0.080593
KCNIP4 Kv channel interacting protein 4 0.080593
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 0.080593
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.080593
THSD7B thrombospondin, type I, domain containing 7B 0.064973
CRP C-reactive protein, pentraxin-related 0.064973
NCOA2 nuclear receptor coactivator 2 0.064973
LAMA1 laminin, alpha 1 0.064973
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.064973
BPTF bromodomain PHD finger transcription factor 0.064973
CDH8 cadherin 8, type 2 0.052255
HHIP hedgehog interacting protein 0.052255
IL1RAP interleukin 1 receptor accessory protein 0.052255
LIPC lipase, hepatic 0.052255
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.043246
C8ORF34 chromosome 8 open reading frame 34 0.043246
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 0.043246
NALCN sodium leak channel, non selective 0.043246
ZBED9 zinc finger, BED-type containing 9 0.035343
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.035343