respiratory chain Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient. (Gene Ontology, GO_0070469)
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Genes

472 proteins co-occuring with the respiratory chain cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 2.19555
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 2.094
CS citrate synthase 2.06996
SOD2 superoxide dismutase 2, mitochondrial 1.91465
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.73309
CLEC3A C-type lectin domain family 3, member A 1.72619
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 1.70383
CLEC2B C-type lectin domain family 2, member B 1.70322
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.69768
CLEC10A C-type lectin domain family 10, member A 1.69461
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.68299
ACO2 aconitase 2, mitochondrial 1.66175
CAT catalase 1.63123
DHODH dihydroorotate dehydrogenase (quinone) 1.60943
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.6071
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.51807
CRYZ crystallin, zeta (quinone reductase) 1.50791
SURF1 surfeit 1 1.4757
SCO2 SCO2 cytochrome c oxidase assembly protein 1.44686
UQCRC2 ubiquinol-cytochrome c reductase core protein II 1.42036
TFAM transcription factor A, mitochondrial 1.41418
GPX1 glutathione peroxidase 1 1.36033
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 1.34392
GPX4 glutathione peroxidase 4 1.34011
GPX5 glutathione peroxidase 5 1.3363
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 1.3325
FXN frataxin 1.30766
FES FES proto-oncogene, tyrosine kinase 1.30121
COX4I1 cytochrome c oxidase subunit IV isoform 1 1.28463
DNAH8 dynein, axonemal, heavy chain 8 1.26445
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.26022
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 1.25232
POLG polymerase (DNA directed), gamma 1.24917
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.24655
ETFDH electron-transferring-flavoprotein dehydrogenase 1.24393
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 1.23505
MDH1 malate dehydrogenase 1, NAD (soluble) 1.23036
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.2179
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.21635
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.21635
UQCRB ubiquinol-cytochrome c reductase binding protein 1.20086
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.20035
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 1.1916
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.17568
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 1.16389
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.16389
COQ9 coenzyme Q9 1.15211
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 1.12858
SCO1 SCO1 cytochrome c oxidase assembly protein 1.11786
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.09696
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 1.07258
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.06853
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 1.06347
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 1.04733
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 1.04532
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.03529
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.03529
NRF1 nuclear respiratory factor 1 1.02679
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 1.00448
CDSN corneodesmosin 1.00202
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.998577
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 0.98683
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.970331
ISCU iron-sulfur cluster assembly enzyme 0.958789
COX5B cytochrome c oxidase subunit Vb 0.95831
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase 0.954961
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.950189
INS insulin 0.940215
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.914376
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.89348
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 0.885166
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 0.884705
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.879633
CAMKMT calmodulin-lysine N-methyltransferase 0.874567
SDHAF1 succinate dehydrogenase complex assembly factor 1 0.865367
NPTX2 neuronal pentraxin II 0.86123
PRDX5 peroxiredoxin 5 0.860311
COX17 COX17 cytochrome c oxidase copper chaperone 0.860311
DGUOK deoxyguanosine kinase 0.857095
SAMHD1 SAM domain and HD domain 1 0.854798
COQ6 coenzyme Q6 monooxygenase 0.850665
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 0.848828
ADCK3 aarF domain containing kinase 3 0.847451
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.847451
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 0.845155
PPARG peroxisome proliferator-activated receptor gamma 0.842859
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.841482
PGLS 6-phosphogluconolactonase 0.841023
GCDH glutaryl-CoA dehydrogenase 0.838728
HK1 hexokinase 1 0.830466
IMMT inner membrane protein, mitochondrial 0.824959
COQ3 coenzyme Q3 methyltransferase 0.813946
TTC19 tetratricopeptide repeat domain 19 0.810735
PHB prohibitin 0.785529
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 0.785529
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 0.785529
FGF21 fibroblast growth factor 21 0.768627
TEAD2 TEA domain family member 2 0.76726
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.766349
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.763617
NNT nicotinamide nucleotide transhydrogenase 0.761342
PFKM phosphofructokinase, muscle 0.761342
COX5A cytochrome c oxidase subunit Va 0.759524
BOLA3 bolA family member 3 0.759069
PREPL prolyl endopeptidase-like 0.757253
COX11 COX11 cytochrome c oxidase copper chaperone 0.748641
GABPB1 GA binding protein transcription factor, beta subunit 1 0.748189
ROMO1 reactive oxygen species modulator 1 0.746381
ETFB electron-transfer-flavoprotein, beta polypeptide 0.738713
NQO1 NAD(P)H dehydrogenase, quinone 1 0.729732
NOS3 nitric oxide synthase 3 (endothelial cell) 0.729284
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.726599
TAZ tafazzin 0.71857
MAOB monoamine oxidase B 0.71457
FH fumarate hydratase 0.711022
GSR glutathione reductase 0.711022
MMD monocyte to macrophage differentiation-associated 0.707039
BAX BCL2-associated X protein 0.706598
TXN thioredoxin 0.70439
MXD3 MAX dimerization protein 3 0.697344
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.692078
GFER growth factor, augmenter of liver regeneration 0.688139
COX20 COX20 cytochrome c oxidase assembly factor 0.687264
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.682463
TMEM70 transmembrane protein 70 0.680284
SUCLG1 succinate-CoA ligase, alpha subunit 0.677673
COX6C cytochrome c oxidase subunit VIc 0.676368
MFN2 mitofusin 2 0.667693
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 0.66726
TYMP thymidine phosphorylase 0.665529
MRPS16 mitochondrial ribosomal protein S16 0.664232
C10ORF2 chromosome 10 open reading frame 2 0.662072
CPT2 carnitine palmitoyltransferase 2 0.657326
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.656464
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 0.645287
COQ4 coenzyme Q4 0.644001
GFM1 G elongation factor, mitochondrial 1 0.638434
MB myoglobin 0.632878
AFG3L2 AFG3-like AAA ATPase 2 0.632451
PKM pyruvate kinase, muscle 0.627335
MPV17 MpV17 mitochondrial inner membrane protein 0.621379
PKLR pyruvate kinase, liver and RBC 0.620104
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 0.618406
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 0.615437
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.615013
TNF tumor necrosis factor 0.606973
SIRT3 sirtuin 3 0.600644
NOX4 NADPH oxidase 4 0.600644
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 0.593912
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.593912
HCCS holocytochrome c synthase 0.592652
PRODH proline dehydrogenase (oxidase) 1 0.584268
CYC1 cytochrome c-1 0.580086
PLA2G1B phospholipase A2, group IB (pancreas) 0.562187
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit 0.558871
NFU1 NFU1 iron-sulfur cluster scaffold 0.5568
ALB albumin 0.555973
TFB2M transcription factor B2, mitochondrial 0.555973
SIRT1 sirtuin 1 0.549773
PC pyruvate carboxylase 0.544411
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.538649
PUS1 pseudouridylate synthase 1 0.537416
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 0.535772
LYRM7 LYR motif containing 7 0.533719
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.531668
SLC25A51 solute carrier family 25, member 51 0.528798
PTCD2 pentatricopeptide repeat domain 2 0.527979
PRELID1 PRELI domain containing 1 0.525113
TNRC6A trinucleotide repeat containing 6A 0.523476
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 0.521023
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 0.519798
MRPS22 mitochondrial ribosomal protein S22 0.519389
AARS2 alanyl-tRNA synthetase 2, mitochondrial 0.51694
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 0.515716
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 0.51164
MT-ATP8 ATP synthase F0 subunit 8 0.503099
UCN urocortin 0.501881
ACAD9 acyl-CoA dehydrogenase family, member 9 0.500664
FDX1L ferredoxin 1-like 0.496205
G6PD glucose-6-phosphate dehydrogenase 0.492157
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.491752
IGLL5 immunoglobulin lambda-like polypeptide 5 0.490944
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 0.488115
CYCS cytochrome c, somatic 0.486904
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 0.483273
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.477233
MFN1 mitofusin 1 0.474822
CREB1 cAMP responsive element binding protein 1 0.466399
FBXL4 F-box and leucine-rich repeat protein 4 0.463598
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 0.461998
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.461998
LYRM4 LYR motif containing 4 0.461199
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.45641
NUBPL nucleotide binding protein-like 0.454816
GSTA1 glutathione S-transferase alpha 1 0.454418
TXN2 thioredoxin 2 0.454418
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.443292
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 0.441312
TFB1M transcription factor B1, mitochondrial 0.438542
GSTA4 glutathione S-transferase alpha 4 0.436565
DLD dihydrolipoamide dehydrogenase 0.43617
HTT huntingtin 0.434985
NDUFA4 NDUFA4, mitochondrial complex associated 0.433012
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 0.429859
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 0.429072
TK2 thymidine kinase 2, mitochondrial 0.428678
MRPL49 mitochondrial ribosomal protein L49 0.423174
PGAM2 phosphoglycerate mutase 2 (muscle) 0.418077
GSTA3 glutathione S-transferase alpha 3 0.417685
GSTA2 glutathione S-transferase alpha 2 0.41612
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 0.414946
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.41182
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.411039
STOML2 stomatin (EPB72)-like 2 0.40714
HSPA4 heat shock 70kDa protein 4 0.405971
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 0.404804
ACO1 aconitase 1, soluble 0.403637
GCG glucagon 0.402859
HMOX1 heme oxygenase 1 0.401693
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 0.399363
PTCD1 pentatricopeptide repeat domain 1 0.397423
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.397035
HFE hemochromatosis 0.397035
C12ORF65 chromosome 12 open reading frame 65 0.392775
TP53 tumor protein p53 0.391615
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.389682
PARP1 poly (ADP-ribose) polymerase 1 0.389296
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.389296
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.389296
ZNF205 zinc finger protein 205 0.386979
COX6B2 cytochrome c oxidase subunit VIb polypeptide 2 (testis) 0.386979
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G 0.385822
FASTKD3 FAST kinase domains 3 0.385436
LDHA lactate dehydrogenase A 0.385436
BPGM 2,3-bisphosphoglycerate mutase 0.383895
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.383509
MTO1 mitochondrial tRNA translation optimization 1 0.383509
PGAM1 phosphoglycerate mutase 1 (brain) 0.382354
BCL2L1 BCL2-like 1 0.380429
MIPEP mitochondrial intermediate peptidase 0.378122
HADH hydroxyacyl-CoA dehydrogenase 0.378122
LRPPRC leucine-rich pentatricopeptide repeat containing 0.375434
ESRRA estrogen-related receptor alpha 0.374283
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.370833
ELANE elastase, neutrophil expressed 0.370067
TACO1 translational activator of mitochondrially encoded cytochrome c oxidase I 0.365859
PMPCB peptidase (mitochondrial processing) beta 0.364331
GUCY2C guanylate cyclase 2C 0.363567
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 0.363185
PINK1 PTEN induced putative kinase 1 0.36204
PRDX3 peroxiredoxin 3 0.361659
MGAM maltase-glucoamylase 0.35899
ATP4B ATPase, H+/K+ exchanging, beta polypeptide 0.357086
COA6 cytochrome c oxidase assembly factor 6 0.357086
NPR1 natriuretic peptide receptor 1 0.355563
MIR210 microRNA 210 0.354802
COA7 cytochrome c oxidase assembly factor 7 (putative) 0.352142
FASTKD1 FAST kinase domains 1 0.351762
MTERF1 mitochondrial transcription termination factor 1 0.351382
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.350622
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.348346
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 0.348346
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.34645
COX8C cytochrome c oxidase subunit VIIIC 0.346071
NGB neuroglobin 0.345314
PHB2 prohibitin 2 0.339639
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.338128
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 0.337373
RTN4IP1 reticulon 4 interacting protein 1 0.333225
COA5 cytochrome c oxidase assembly factor 5 0.332095
ACBD6 acyl-CoA binding domain containing 6 0.330966
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.330589
SLC25A27 solute carrier family 25, member 27 0.327581
HK2 hexokinase 2 0.326078
AOX1 aldehyde oxidase 1 0.323825
THTPA thiamine triphosphatase 0.318953
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 0.318205
POLRMT polymerase (RNA) mitochondrial (DNA directed) 0.317082
BCL2 B-cell CLL/lymphoma 2 0.31596
RBM41 RNA binding motif protein 41 0.315212
YARS tyrosyl-tRNA synthetase 0.314839
TST thiosulfate sulfurtransferase (rhodanese) 0.309986
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.302168
CNOT4 CCR4-NOT transcription complex, subunit 4 0.302168
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 0.298455
MRPS2 mitochondrial ribosomal protein S2 0.298455
CLK1 CDC-like kinase 1 0.298084
PGS1 phosphatidylglycerophosphate synthase 1 0.296972
ADPGK ADP-dependent glucokinase 0.29586
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 0.295119
JUN jun proto-oncogene 0.293637
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.291787
LRRK2 leucine-rich repeat kinase 2 0.291417
FOXRED1 FAD-dependent oxidoreductase domain containing 1 0.291417
ACTBL2 actin, beta-like 2 0.291047
ADCK2 aarF domain containing kinase 2 0.290678
FASTKD2 FAST kinase domains 2 0.287352
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.287352
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.286983
ADCK4 aarF domain containing kinase 4 0.286983
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 0.281821
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase 0.281821
CYB5A cytochrome b5 type A (microsomal) 0.279245
DUOX2 dual oxidase 2 0.275202
GLRX2 glutaredoxin 2 0.275202
NADK2 NAD kinase 2, mitochondrial 0.274468
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 0.274101
COA3 cytochrome c oxidase assembly factor 3 0.272633
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.268237
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.266408
PYGM phosphorylase, glycogen, muscle 0.264946
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.264215
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 0.26385
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.26385
VEGFA vascular endothelial growth factor A 0.26239
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 0.262025
UQCC3 ubiquinol-cytochrome c reductase complex assembly factor 3 0.260931
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 0.260202
PPIF peptidylprolyl isomerase F 0.259837
COMT catechol-O-methyltransferase 0.258381
SSBP1 single-stranded DNA binding protein 1, mitochondrial 0.258381
ALAS1 5'-aminolevulinate synthase 1 0.256925
LIAS lipoic acid synthetase 0.25547
ACTG1 actin gamma 1 0.254743
FECH ferrochelatase 0.254017
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 0.253291
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 0.252202
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.251114
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 0.250026
PPARA peroxisome proliferator-activated receptor alpha 0.249664
PTEN phosphatase and tensin homolog 0.249664
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.24894
GAMT guanidinoacetate N-methyltransferase 0.24713
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) 0.246046
HMBS hydroxymethylbilane synthase 0.246046
CKB creatine kinase, brain 0.244601
ACTB actin, beta 0.243158
MECP2 methyl CpG binding protein 2 0.238837
PGK1 phosphoglycerate kinase 1 0.238837
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 0.23776
CYGB cytoglobin 0.237042
PRDX4 peroxiredoxin 4 0.236683
GLS2 glutaminase 2 (liver, mitochondrial) 0.234891
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.234891
AGK acylglycerol kinase 0.233817
CHDH choline dehydrogenase 0.230601
NFS1 NFS1 cysteine desulfurase 0.229888
OXA1L oxidase (cytochrome c) assembly 1-like 0.229532
CP ceruloplasmin (ferroxidase) 0.228464
ELAC2 elaC ribonuclease Z 2 0.227397
PARK7 parkinson protein 7 0.224558
PYGL phosphorylase, glycogen, liver 0.222083
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.22173
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.22173
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.220321
COX19 COX19 cytochrome c oxidase assembly factor 0.219969
SUOX sulfite oxidase 0.218914
ATPIF1 ATPase inhibitory factor 1 0.21681
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.21646
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 0.21646
NOX1 NADPH oxidase 1 0.216111
PRDX2 peroxiredoxin 2 0.216111
TF transferrin 0.212974
DARS aspartyl-tRNA synthetase 0.212974
RET ret proto-oncogene 0.210894
MRPS27 mitochondrial ribosomal protein S27 0.210203
OLFML3 olfactomedin-like 3 0.209858
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 0.209858
CHKB choline kinase beta 0.208137
COX18 COX18 cytochrome c oxidase assembly factor 0.204378
PLEKHM3 pleckstrin homology domain containing, family M, member 3 0.202346
LEP leptin 0.201335
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 0.200328
SIRT7 sirtuin 7 0.199993
SIRT4 sirtuin 4 0.19733
TH tyrosine hydroxylase 0.195353
CYBB cytochrome b-245, beta polypeptide 0.194698
MRPS11 mitochondrial ribosomal protein S11 0.194371
SIRT5 sirtuin 5 0.193719
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 0.19307
HIST1H2BE histone cluster 1, H2be 0.190495
HIST1H2BI histone cluster 1, H2bi 0.190495
HIST1H2BG histone cluster 1, H2bg 0.190495
MPO myeloperoxidase 0.190175
ANXA5 annexin A5 0.189539
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.187333
PDK2 pyruvate dehydrogenase kinase, isozyme 2 0.18702
TSEN54 TSEN54 tRNA splicing endonuclease subunit 0.186708
BDH1 3-hydroxybutyrate dehydrogenase, type 1 0.185777
NOS2 nitric oxide synthase 2, inducible 0.185469
GLRX5 glutaredoxin 5 0.184241
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 0.183631
ALAS2 5'-aminolevulinate synthase 2 0.182723
CFL1 cofilin 1 (non-muscle) 0.180634
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.178877
DUOX1 dual oxidase 1 0.177724
PYGB phosphorylase, glycogen; brain 0.17687
SDHAF3 succinate dehydrogenase complex assembly factor 3 0.174635
MSRA methionine sulfoxide reductase A 0.174361
BCHE butyrylcholinesterase 0.173543
PRDX1 peroxiredoxin 1 0.173273
RIC8A RIC8 guanine nucleotide exchange factor A 0.172468
SIRT6 sirtuin 6 0.170629
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.170371
SIRT2 sirtuin 2 0.170114
BTD biotinidase 0.169859
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.16935
PGC progastricsin (pepsinogen C) 0.168349
INSC inscuteable homolog (Drosophila) 0.166405
PKNOX1 PBX/knotted 1 homeobox 1 0.165697
L2HGDH L-2-hydroxyglutarate dehydrogenase 0.165463
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.165231
UPP1 uridine phosphorylase 1 0.165231
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.1632
MTG1 mitochondrial ribosome-associated GTPase 1 0.162763
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 0.162117
ASPRV1 aspartic peptidase, retroviral-like 1 0.162117
STK11 serine/threonine kinase 11 0.161068
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.160863
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) 0.160254
MRPL40 mitochondrial ribosomal protein L40 0.160053
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.159074
EDN1 endothelin 1 0.158129
NF1 neurofibromin 1 0.158129
MAPK8 mitogen-activated protein kinase 8 0.15776
CCDC62 coiled-coil domain containing 62 0.156342
NSUN4 NOP2/Sun domain family, member 4 0.156342
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 0.135064
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 0.134322
FDXR ferredoxin reductase 0.13431
ECSIT ECSIT signalling integrator 0.134106
COX7B cytochrome c oxidase subunit VIIb 0.133884
VARS valyl-tRNA synthetase 0.133739
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.133604
DDT D-dopachrome tautomerase 0.133536
CTU1 cytosolic thiouridylase subunit 1 0.133482
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 0.133455
SESN3 sestrin 3 0.133358
CRTC3 CREB regulated transcription coactivator 3 0.133177
EIF2A eukaryotic translation initiation factor 2A, 65kDa 0.133149
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.133106
SPATA21 spermatogenesis associated 21 0.132731
ZDHHC8 zinc finger, DHHC-type containing 8 0.132372
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 0.132281
GSX2 GS homeobox 2 0.132158
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.132142
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 0.131875
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria 0.131859
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 0.131779
TRIT1 tRNA isopentenyltransferase 1 0.131731
ESR2 estrogen receptor 2 (ER beta) 0.131714
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) 0.131714
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.131698
IFNB1 interferon, beta 1, fibroblast 0.131552
HMOX2 heme oxygenase 2 0.131353
HAP1 huntingtin-associated protein 1 0.131013
FBXO44 F-box protein 44 0.130375
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.130338
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 0.13032
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.13008
TXNRD1 thioredoxin reductase 1 0.129814
NUAK1 NUAK family, SNF1-like kinase, 1 0.129484
INSR insulin receptor 0.129245
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.129041
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.12898
LIPT1 lipoyltransferase 1 0.128938
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.128834
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.128581
GCLC glutamate-cysteine ligase, catalytic subunit 0.128538
FSTL1 follistatin-like 1 0.128366
ARHGAP6 Rho GTPase activating protein 6 0.128278
SIGLEC8 sialic acid binding Ig-like lectin 8 0.128168