resistant Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

440 genes co-occuring with the biological term resistant in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACP5 acid phosphatase 5, tartrate resistant
ADAM12 ADAM metallopeptidase domain 12
ADAM9 ADAM metallopeptidase domain 9
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIP aryl hydrocarbon receptor interacting protein
AKR1C3 aldo-keto reductase family 1, member C3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALKBH7 alkB, alkylation repair homolog 7 (E. coli)
ALOX15 arachidonate 15-lipoxygenase
ANGPTL2 angiopoietin-like 2
ANPEP alanyl (membrane) aminopeptidase
ANXA2 annexin A2
API5 apoptosis inhibitor 5
APOB apolipoprotein B
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
AR androgen receptor
AREG amphiregulin
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATM ATM serine/threonine kinase
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
AURKA aurora kinase A
AURKB aurora kinase B
BAG3 BCL2-associated athanogene 3
BAK1 BCL2-antagonist/killer 1
BASP1 brain abundant, membrane attached signal protein 1
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BFAR bifunctional apoptosis regulator
BHMT betaine--homocysteine S-methyltransferase
BIRC2 baculoviral IAP repeat containing 2
BIRC5 baculoviral IAP repeat containing 5
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BSG basigin (Ok blood group)
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALR calreticulin
CAMP cathelicidin antimicrobial peptide
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAT catalase
CCKBR cholecystokinin B receptor
CCNE2 cyclin E2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD1D CD1d molecule
CD34 CD34 molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CDA cytidine deaminase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHKA choline kinase alpha
CHUK conserved helix-loop-helix ubiquitous kinase
CLU clusterin
CPB2 carboxypeptidase B2 (plasma)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRYGD crystallin, gamma D
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTCF CCCTC-binding factor (zinc finger protein)
CXCR1 chemokine (C-X-C motif) receptor 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DEFA5 defensin, alpha 5, Paneth cell-specific
DHFR dihydrofolate reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DMC1 DNA meiotic recombinase 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DRD2 dopamine receptor D2
DSG2 desmoglein 2
DVL1P1 dishevelled segment polarity protein 1 pseudogene 1
DVL3 dishevelled segment polarity protein 3
E2F1 E2F transcription factor 1
E2F4 E2F transcription factor 4, p107/p130-binding
EGFR epidermal growth factor receptor
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF4E eukaryotic translation initiation factor 4E
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC1 excision repair cross-complementation group 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERLIN2 ER lipid raft associated 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV4 ets variant 4
F13A1 coagulation factor XIII, A1 polypeptide
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FAT1 FAT atypical cadherin 1
FCN3 ficolin (collagen/fibrinogen domain containing) 3
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF1 fibroblast growth factor 1 (acidic)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FKBP4 FK506 binding protein 4, 59kDa
FLT4 fms-related tyrosine kinase 4
FOLR1 folate receptor 1 (adult)
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FTO fat mass and obesity associated
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAL galanin/GMAP prepropeptide
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GH1 growth hormone 1
GIPR gastric inhibitory polypeptide receptor
GLI2 GLI family zinc finger 2
GLS2 glutaminase 2 (liver, mitochondrial)
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPI glucose-6-phosphate isomerase
GPX1 glutathione peroxidase 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSK3B glycogen synthase kinase 3 beta
GSTA4 glutathione S-transferase alpha 4
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
HABP2 hyaluronan binding protein 2
HAMP hepcidin antimicrobial peptide
HDAC3 histone deacetylase 3
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLF hepatic leukemia factor
HMOX1 heme oxygenase 1
HOXC11 homeobox C11
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
IDO1 indoleamine 2,3-dioxygenase 1
IER3 immediate early response 3
IFIH1 interferon induced with helicase C domain 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL13 interleukin 13
IL1A interleukin 1, alpha
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL4 interleukin 4
IL6 interleukin 6
IL7R interleukin 7 receptor
IMPACT impact RWD domain protein
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INS insulin
INSR insulin receptor
IRF2 interferon regulatory factor 2
IRS1 insulin receptor substrate 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNK2 potassium channel, two pore domain subfamily K, member 2
KDR kinase insert domain receptor
KIF2C kinesin family member 2C
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF5 Kruppel-like factor 5 (intestinal)
KLK3 kallikrein-related peptidase 3
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT18 keratin 18, type I
KRT5 keratin 5, type II
KRT8 keratin 8, type II
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN2 lipocalin 2
LEP leptin
LGALS3 lectin, galactoside-binding, soluble, 3
LIMK2 LIM domain kinase 2
LPL lipoprotein lipase
LRRK2 leucine-rich repeat kinase 2
MAL mal, T-cell differentiation protein
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCL1 myeloid cell leukemia 1
MDK midkine (neurite growth-promoting factor 2)
MECOM MDS1 and EVI1 complex locus
MEN1 multiple endocrine neoplasia I
MEPE matrix extracellular phosphoglycoprotein
MET MET proto-oncogene, receptor tyrosine kinase
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MGMT O-6-methylguanine-DNA methyltransferase
MIR130B microRNA 130b
MIR145 microRNA 145
MIR146A microRNA 146a
MIR195 microRNA 195
MIR221 microRNA 221
MIR222 microRNA 222
MIR23B microRNA 23b
MIR27B microRNA 27b
MIR495 microRNA 495
MKI67 marker of proliferation Ki-67
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLH1 mutL homolog 1
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MRGPRX2 MAS-related GPR, member X2
MSTN myostatin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MVP major vault protein
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYOD1 myogenic differentiation 1
NANOG Nanog homeobox
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCAM1 neural cell adhesion molecule 1
NCOA1 nuclear receptor coactivator 1
NEK11 NIMA-related kinase 11
NEK6 NIMA-related kinase 6
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGF nerve growth factor (beta polypeptide)
NINL ninein-like
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDCD1 programmed cell death 1
PDGFB platelet-derived growth factor beta polypeptide
PDGFD platelet derived growth factor D
PEA15 phosphoprotein enriched in astrocytes 15
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLG plasminogen
PLIN1 perilipin 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNPLA3 patatin-like phospholipase domain containing 3
POLK polymerase (DNA directed) kappa
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCA protein kinase C, alpha
PRKCZ protein kinase C, zeta
PRNP prion protein
PROM1 prominin 1
PRSS3 protease, serine, 3
PSIP1 PC4 and SFRS1 interacting protein 1
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RB1 retinoblastoma 1
RBL2 retinoblastoma-like 2
RCAN1 regulator of calcineurin 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REPS2 RALBP1 associated Eps domain containing 2
REST RE1-silencing transcription factor
RETN resistin
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RHOBTB2 Rho-related BTB domain containing 2
RNLS renalase, FAD-dependent amine oxidase
RPL6 ribosomal protein L6
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RRM1 ribonucleotide reductase M1
RUNX1 runt-related transcription factor 1
S100A11 S100 calcium binding protein A11
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAA1 serum amyloid A1
SAMHD1 SAM domain and HD domain 1
SCARB1 scavenger receptor class B, member 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SDC1 syndecan 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHBG sex hormone-binding globulin
SHH sonic hedgehog
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SLPI secretory leukocyte peptidase inhibitor
SMAD7 SMAD family member 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SND1 staphylococcal nuclease and tudor domain containing 1
SOCS3 suppressor of cytokine signaling 3
SOCS7 suppressor of cytokine signaling 7
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPDEF SAM pointed domain containing ETS transcription factor
SPHK2 sphingosine kinase 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRI sorcin
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STK11 serine/threonine kinase 11
STXBP3 syntaxin binding protein 3
SYCP3 synaptonemal complex protein 3
SYK spleen tyrosine kinase
TCF3 transcription factor 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCL1A T-cell leukemia/lymphoma 1A
TDGF1 teratocarcinoma-derived growth factor 1
TERC telomerase RNA component
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THRB thyroid hormone receptor, beta
TK1 thymidine kinase 1, soluble
TK2 thymidine kinase 2, mitochondrial
TLR4 toll-like receptor 4
TMPRSS15 transmembrane protease, serine 15
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP73 tumor protein p73
TRIM28 tripartite motif containing 28
TRIM5 tripartite motif containing 5
TUBB3 tubulin, beta 3 class III
TXNRD2 thioredoxin reductase 2
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
USP9X ubiquitin specific peptidase 9, X-linked
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VKORC1 vitamin K epoxide reductase complex, subunit 1
VRK1 vaccinia related kinase 1
VWF von Willebrand factor
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNF43 zinc finger protein 43
ZNRD1 zinc ribbon domain containing 1