repaglinide-3558 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the repaglinide-3558 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMACR alpha-methylacyl-CoA racemase
ANP32A-IT1 ANP32A intronic transcript 1
APOC4 apolipoprotein C-IV
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATM ATM serine/threonine kinase
ATXN7L3B ataxin 7-like 3B
BAIAP3 BAI1-associated protein 3
BCL3 B-cell CLL/lymphoma 3
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C10ORF12 chromosome 10 open reading frame 12
C19ORF57 chromosome 19 open reading frame 57
CA1 carbonic anhydrase I
CACTIN cactin, spliceosome C complex subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC181 coiled-coil domain containing 181
CCDC87 coiled-coil domain containing 87
CD52 CD52 molecule
CDRT1 CMT1A duplicated region transcript 1
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLCN4 chloride channel, voltage-sensitive 4
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTNAP2 contactin associated protein-like 2
CRIP1 cysteine-rich protein 1 (intestinal)
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CXORF21 chromosome X open reading frame 21
DBP D site of albumin promoter (albumin D-box) binding protein
DENND5B DENN/MADD domain containing 5B
DFNB31 deafness, autosomal recessive 31
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ECE1 endothelin converting enzyme 1
EFNA3 ephrin-A3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EXOSC2 exosome component 2
FLT1 fms-related tyrosine kinase 1
FXYD2 FXYD domain containing ion transport regulator 2
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GPSM3 G-protein signaling modulator 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HSF4 heat shock transcription factor 4
ICAM5 intercellular adhesion molecule 5, telencephalin
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1B interleukin 1, beta
INSL4 insulin-like 4 (placenta)
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KATNB1 katanin p80 (WD repeat containing) subunit B 1
LAMC2 laminin, gamma 2
LMAN1 lectin, mannose-binding, 1
LMO7 LIM domain 7
MAN2A2 mannosidase, alpha, class 2A, member 2
MTSS1 metastasis suppressor 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYRIP myosin VIIA and Rab interacting protein
NAG18 NAG18 mRNA
NBL1 neuroblastoma 1, DAN family BMP antagonist
NECAB2 N-terminal EF-hand calcium binding protein 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NMUR1 neuromedin U receptor 1
NTF3 neurotrophin 3
PCDH12 protocadherin 12
PLK3 polo-like kinase 3
POU4F1 POU class 4 homeobox 1
PPY pancreatic polypeptide
PTHLH parathyroid hormone-like hormone
QKI QKI, KH domain containing, RNA binding
RAB3B RAB3B, member RAS oncogene family
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RB1 retinoblastoma 1
RNF144A ring finger protein 144A
RNF19B ring finger protein 19B
S100A8 S100 calcium binding protein A8
SBNO1 strawberry notch homolog 1 (Drosophila)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SETBP1 SET binding protein 1
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SMAD1 SMAD family member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCAIP synuclein, alpha interacting protein
SPTBN1 spectrin, beta, non-erythrocytic 1
SRPK2 SRSF protein kinase 2
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBX3 T-box 3
TEP1 telomerase-associated protein 1
TFEB transcription factor EB
TONSL tonsoku-like, DNA repair protein
UBXN1 UBX domain protein 1
USP2 ubiquitin specific peptidase 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPRBP Vpr (HIV-1) binding protein
XCR1 chemokine (C motif) receptor 1
ZFP2 ZFP2 zinc finger protein
ZNF442 zinc finger protein 442
ZNF500 zinc finger protein 500
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTL8 actin-like 8
ADAM15 ADAM metallopeptidase domain 15
ADCY7 adenylate cyclase 7
APOD apolipoprotein D
BBS10 Bardet-Biedl syndrome 10
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
C16ORF45 chromosome 16 open reading frame 45
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5ORF45 chromosome 5 open reading frame 45
CALCOCO1 calcium binding and coiled-coil domain 1
CAMTA1 calmodulin binding transcription activator 1
CCDC132 coiled-coil domain containing 132
CCDC88C coiled-coil domain containing 88C
CCNO cyclin O
CCNT1 cyclin T1
CCP110 centriolar coiled coil protein 110kDa
CD82 CD82 molecule
CGA glycoprotein hormones, alpha polypeptide
CHML choroideremia-like (Rab escort protein 2)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CORT cortistatin
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
CUZD1 CUB and zona pellucida-like domains 1
CXADR coxsackie virus and adenovirus receptor
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
FBXL7 F-box and leucine-rich repeat protein 7
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HIST1H2BC histone cluster 1, H2bc
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HS1BP3 HCLS1 binding protein 3
INCENP inner centromere protein antigens 135/155kDa
JUNB jun B proto-oncogene
KIAA0125 KIAA0125
KIFC1 kinesin family member C1
KLF7 Kruppel-like factor 7 (ubiquitous)
LAMB1 laminin, beta 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHX6 LIM homeobox 6
LINC00597 long intergenic non-protein coding RNA 597
LOC257152 uncharacterized LOC257152
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A2 leucine rich repeat containing 37, member A2
LY6D lymphocyte antigen 6 complex, locus D
MAP1S microtubule-associated protein 1S
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFSD12 major facilitator superfamily domain containing 12
NACA2 nascent polypeptide-associated complex alpha subunit 2
NECAP2 NECAP endocytosis associated 2
NPM3 nucleophosmin/nucleoplasmin 3
NT5DC3 5'-nucleotidase domain containing 3
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARD6A par-6 family cell polarity regulator alpha
PITX2 paired-like homeodomain 2
PKN1 protein kinase N1
PP14571 uncharacterized LOC100130449
PRSS22 protease, serine, 22
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTK6 protein tyrosine kinase 6
RHOBTB1 Rho-related BTB domain containing 1
RNF126P1 ring finger protein 126 pseudogene 1
RPGRIP1L RPGRIP1-like
RPL10L ribosomal protein L10-like
RUNDC3B RUN domain containing 3B
SCGB2A2 secretoglobin, family 2A, member 2
SIX1 SIX homeobox 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SP1 Sp1 transcription factor
STX1A syntaxin 1A (brain)
SULT4A1 sulfotransferase family 4A, member 1
SYCP2 synaptonemal complex protein 2
THRAP3 thyroid hormone receptor associated protein 3
TM6SF1 transmembrane 6 superfamily member 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TPST1 tyrosylprotein sulfotransferase 1
TRIM25 tripartite motif containing 25
TRPV1 transient receptor potential cation channel, subfamily V, member 1
URM1 ubiquitin related modifier 1
USB1 U6 snRNA biogenesis 1
ZC3H3 zinc finger CCCH-type containing 3
ZNF205 zinc finger protein 205
ZNF571 zinc finger protein 571