renal hypertension Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

172 genes co-occuring with the disease renal hypertension in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
REN renin 3.30088
ACE angiotensin I converting enzyme 2.26744
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 1.56889
NPPA natriuretic peptide A 1.36074
ADRB1 adrenoceptor beta 1 1.31974
KNG1 kininogen 1 1.28173
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.03956
ALB albumin 1.01385
SLC22A10 solute carrier family 22, member 10 0.948685
TGFB1 transforming growth factor, beta 1 0.8741
MYH9 myosin, heavy chain 9, non-muscle 0.853221
AGTR1 angiotensin II receptor, type 1 0.81018
APOL1 apolipoprotein L, 1 0.804026
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 0.799103
PNMT phenylethanolamine N-methyltransferase 0.797872
FBXL20 F-box and leucine-rich repeat protein 20 0.795821
DNAH8 dynein, axonemal, heavy chain 8 0.781888
FN1 fibronectin 1 0.779432
MPV17 MpV17 mitochondrial inner membrane protein 0.762271
CLIP1 CAP-GLY domain containing linker protein 1 0.722482
EDN1 endothelin 1 0.716021
AVP arginine vasopressin 0.713198
NOS3 nitric oxide synthase 3 (endothelial cell) 0.693499
EDNRA endothelin receptor type A 0.683892
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 0.67312
ADM adrenomedullin 0.661197
LYZ lysozyme 0.656837
SOD2 superoxide dismutase 2, mitochondrial 0.629635
RND3 Rho family GTPase 3 0.585108
C5ORF38 chromosome 5 open reading frame 38 0.581996
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.563723
CD79A CD79a molecule, immunoglobulin-associated alpha 0.562558
NF1 neurofibromin 1 0.530768
APLNR apelin receptor 0.520731
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.496557
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.495029
CABIN1 calcineurin binding protein 1 0.487407
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.476014
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.451078
KPNA3 karyopherin alpha 3 (importin alpha 4) 0.443171
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.434148
SMTN smoothelin 0.420641
HMOX1 heme oxygenase 1 0.420266
EPHX2 epoxide hydrolase 2, cytoplasmic 0.408292
POMC proopiomelanocortin 0.407545
MUC20 mucin 20, cell surface associated 0.396353
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 0.395608
PEX3 peroxisomal biogenesis factor 3 0.38111
DUOX1 dual oxidase 1 0.374068
NOX4 NADPH oxidase 4 0.371477
MYOZ2 myozenin 2 0.36741
DNPEP aspartyl aminopeptidase 0.357446
DUOX2 dual oxidase 2 0.354131
SPP1 secreted phosphoprotein 1 0.351923
GRK4 G protein-coupled receptor kinase 4 0.348246
ACE2 angiotensin I converting enzyme 2 0.346409
A1CF APOBEC1 complementation factor 0.346042
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.345675
MMP2 matrix metallopeptidase 2 0.343473
TH tyrosine hydroxylase 0.341639
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.336144
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.335412
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.324823
CARTPT CART prepropeptide 0.320454
MOBP myelin-associated oligodendrocyte basic protein 0.317545
PDGFA platelet-derived growth factor alpha polypeptide 0.317182
ACRBP acrosin binding protein 0.316456
MLPH melanophilin 0.309566
GPS1 G protein pathway suppressor 1 0.306672
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.306672
MADD MAP-kinase activating death domain 0.304503
CALCRL calcitonin receptor-like 0.300894
KLK15 kallikrein-related peptidase 15 0.298731
TPSG1 tryptase gamma 1 0.294772
BEST3 bestrophin 3 0.290103
CAT catalase 0.287235
B2M beta-2-microglobulin 0.282582
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.276158
NTSR1 neurotensin receptor 1 (high affinity) 0.274732
SYNPO synaptopodin 0.264431
RHOB ras homolog family member B 0.264077
COL8A1 collagen, type VIII, alpha 1 0.25983
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.253479
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.252774
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.246799
CALCA calcitonin-related polypeptide alpha 0.246799
NPY neuropeptide Y 0.242245
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 0.232836
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.225573
GHR growth hormone receptor 0.225229
RNPEP arginyl aminopeptidase (aminopeptidase B) 0.220766
IL4I1 interleukin 4 induced 1 0.217012
CTGF connective tissue growth factor 0.210253
INS insulin 0.209918
PTPRO protein tyrosine phosphatase, receptor type, O 0.209248
KL klotho 0.200982
GJA5 gap junction protein, alpha 5, 40kDa 0.200982
CHGA chromogranin A 0.198064
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.191097
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.187113
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.186811
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 0.183835
AMT aminomethyltransferase 0.180937
ERAS ES cell expressed Ras 0.180367
SGK1 serum/glucocorticoid regulated kinase 1 0.17952
BMP5 bone morphogenetic protein 5 0.17952
EDA ectodysplasin A 0.176485
CCL2 chemokine (C-C motif) ligand 2 0.170789
THOP1 thimet oligopeptidase 1 0.165217
FOS FBJ murine osteosarcoma viral oncogene homolog 0.164571
YME1L1 YME1-like 1 ATPase 0.164571
PGF placental growth factor 0.162707
CTSA cathepsin A 0.158266
ADIPOQ adiponectin, C1Q and collagen domain containing 0.142777
COL8A2 collagen, type VIII, alpha 2 0.142506
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.142501
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.14228
SMOX spermine oxidase 0.142181
PTH parathyroid hormone 0.142085
MIR192 microRNA 192 0.141702
SDCBP syndecan binding protein (syntenin) 0.141495
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.141225
KRT3 keratin 3, type II 0.141194
SZRD1 SUZ RNA binding domain containing 1 0.14073
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.140687
PDGFB platelet-derived growth factor beta polypeptide 0.140567
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.140523
JAG1 jagged 1 0.140389
DCN decorin 0.1401
PAOX polyamine oxidase (exo-N4-amino) 0.139814
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.139702
FGB fibrinogen beta chain 0.139598
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.139545
PAX4 paired box 4 0.13908
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.138929
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.13881
PPT2 palmitoyl-protein thioesterase 2 0.138725
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.138602
TSN translin 0.138526
S100G S100 calcium binding protein G 0.138437
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.138282
GCDH glutaryl-CoA dehydrogenase 0.138203
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.138083
LAT linker for activation of T cells 0.138001
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.137974
SUMF1 sulfatase modifying factor 1 0.137835
ANPEP alanyl (membrane) aminopeptidase 0.137549
SACS sacsin molecular chaperone 0.137341
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 0.137296
TGFB2 transforming growth factor, beta 2 0.137204
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 0.137127
DCPS decapping enzyme, scavenger 0.13708
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 0.137065
EGR1 early growth response 1 0.136986
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.136597
RAMP2 receptor (G protein-coupled) activity modifying protein 2 0.136187
MME membrane metallo-endopeptidase 0.135956
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.135865
MLXIPL MLX interacting protein-like 0.135452
MPO myeloperoxidase 0.135297
PCNA proliferating cell nuclear antigen 0.135277
MUL1 mitochondrial E3 ubiquitin protein ligase 1 0.135277
ACTN4 actinin, alpha 4 0.135139
NPR3 natriuretic peptide receptor 3 0.135038
NID1 nidogen 1 0.135038
YBX1 Y box binding protein 1 0.134895
MATN1 matrilin 1, cartilage matrix protein 0.134895
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.134895
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.134854
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.134729
CPN1 carboxypeptidase N, polypeptide 1 0.134408
CPA6 carboxypeptidase A6 0.134386