renal clear cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A renal cell carcinoma that has_material_basis_in cells that appear very pale or clear when examined under microscope. (Human Disease Ontology, DOID_4467)
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Genes

119 genes co-occuring with the disease renal clear cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 1.5476
CUL2 cullin 2 1.26603
SPAG4 sperm associated antigen 4 1.26037
RHEBL1 Ras homolog enriched in brain like 1 1.23299
DIRC2 disrupted in renal carcinoma 2 1.20483
CA9 carbonic anhydrase IX 1.16307
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 1.09587
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 1.0795
BNC1 basonuclin 1 1.03577
ITPKA inositol-trisphosphate 3-kinase A 1.01723
KRT7 keratin 7, type II 1.0071
PRCC papillary renal cell carcinoma (translocation-associated) 1.00161
PDCD5 programmed cell death 5 0.9717
CADM4 cell adhesion molecule 4 0.937459
FHIT fragile histidine triad 0.922149
ETF1 eukaryotic translation termination factor 1 0.888848
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.865093
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.862637
EGLN2 egl-9 family hypoxia-inducible factor 2 0.861409
SHARPIN SHANK-associated RH domain interactor 0.832738
KHK ketohexokinase (fructokinase) 0.824128
SOSTDC1 sclerostin domain containing 1 0.820437
ANGPT4 angiopoietin 4 0.801154
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.791721
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.78066
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) 0.766759
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.748424
FZD3 frizzled class receptor 3 0.73746
YBX3 Y box binding protein 3 0.716021
MAML1 mastermind-like 1 (Drosophila) 0.694301
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.678701
CDCP1 CUB domain containing protein 1 0.661594
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 0.65565
PNN pinin, desmosome associated protein 0.65565
STK10 serine/threonine kinase 10 0.655254
PLIN3 perilipin 3 0.648533
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.622967
ELAVL1 ELAV like RNA binding protein 1 0.594843
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.588612
PBRM1 polybromo 1 0.577716
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 0.566054
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.55518
ESM1 endothelial cell-specific molecule 1 0.55518
TFE3 transcription factor binding to IGHM enhancer 3 0.550911
HAS3 hyaluronan synthase 3 0.539667
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.538506
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.531154
MUC1 mucin 1, cell surface associated 0.509192
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 0.503824
HMBS hydroxymethylbilane synthase 0.496939
NNMT nicotinamide N-methyltransferase 0.49274
MSLN mesothelin 0.492359
FSCN1 fascin actin-bundling protein 1 0.489691
UBIAD1 UbiA prenyltransferase domain containing 1 0.478289
BHMT betaine--homocysteine S-methyltransferase 0.469954
MIRLET7C microRNA let-7c 0.461261
GSN gelsolin 0.447311
KRT20 keratin 20, type I 0.435651
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.434148
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 0.431894
FCGRT Fc fragment of IgG, receptor, transporter, alpha 0.429266
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.429266
TP53 tumor protein p53 0.428891
ANXA4 annexin A4 0.418768
UPK3A uroplakin 3A 0.414276
EGLN3 egl-9 family hypoxia-inducible factor 3 0.409414
MYEF2 myelin expression factor 2 0.402692
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.399707
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.391885
HAS2 hyaluronan synthase 2 0.380368
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.379997
TXNRD2 thioredoxin reductase 2 0.379626
RHEB Ras homolog enriched in brain 0.374809
KRT14 keratin 14, type I 0.372958
CUBN cubilin (intrinsic factor-cobalamin receptor) 0.366301
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.362609
KIF1B kinesin family member 1B 0.351555
PRAME preferentially expressed antigen in melanoma 0.348246
ARID1A AT rich interactive domain 1A (SWI-like) 0.34384
TBL2 transducin (beta)-like 2 0.337242
ANGPTL4 angiopoietin-like 4 0.335412
MIR222 microRNA 222 0.312827
MEF2C myocyte enhancer factor 2C 0.309204
TG thyroglobulin 0.308842
CTTN cortactin 0.30631
MLANA melan-A 0.30342
GAS6 growth arrest-specific 6 0.295851
BMP6 bone morphogenetic protein 6 0.295132
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.291898
PEBP1 phosphatidylethanolamine binding protein 1 0.285444
SGK1 serum/glucocorticoid regulated kinase 1 0.268687
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.260184
SFN stratifin 0.252774
FSCN3 fascin actin-bundling protein 3, testicular 0.241196
MIR221 microRNA 221 0.238752
FBN2 fibrillin 2 0.237706
CCNA2 cyclin A2 0.21974
FSCN2 fascin actin-bundling protein 2, retinal 0.216672
MMP10 matrix metallopeptidase 10 0.213959
MIR145 microRNA 145 0.210925
AXL AXL receptor tyrosine kinase 0.204923
HAS1 hyaluronan synthase 1 0.200656
MET MET proto-oncogene, receptor tyrosine kinase 0.199681
PML promyelocytic leukemia 0.196779
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.196459
MIR17 microRNA 17 0.192031
SFRP1 secreted frizzled-related protein 1 0.191719
WNT3A wingless-type MMTV integration site family, member 3A 0.189859
CDC25A cell division cycle 25A 0.184424
MUC4 mucin 4, cell surface associated 0.177301
NQO1 NAD(P)H dehydrogenase, quinone 1 0.176215
KLF10 Kruppel-like factor 10 0.174881
TGFBI transforming growth factor, beta-induced, 68kDa 0.173832
DES desmin 0.171785
LRP2 low density lipoprotein receptor-related protein 2 0.170789
KRT8 keratin 8, type II 0.170544
PDPN podoplanin 0.166095
EGR1 early growth response 1 0.163523
MUC6 mucin 6, oligomeric mucus/gel-forming 0.15948