renal cell carcinoma Gene Set

Dataset HPO Gene-Disease Associations
Category disease or phenotype associations
Type phenotype
Description A renal carcinoma that has_material_basis_in the lining of the proximal convoluted renal tubule of the kidney. (Human Disease Ontology, DOID_4450)
External Link http://compbio.charite.de/hpoweb/showterm?id=HP:0005584
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Genes

32 genes associated with the renal cell carcinoma phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
APC adenomatous polyposis coli
AXIN2 axin 2
BAX BCL2-associated X protein
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CDC73 cell division cycle 73
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DCC DCC netrin 1 receptor
DIRC2 disrupted in renal carcinoma 2
EP300 E1A binding protein p300
FGFR3 fibroblast growth factor receptor 3
FLCN folliculin
FN1 fibronectin 1
HNF1A HNF1 homeobox A
MCC mutated in colorectal cancers
MET MET proto-oncogene, receptor tyrosine kinase
MLH3 mutL homolog 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OGG1 8-oxoguanine DNA glycosylase
PDGFRL platelet-derived growth factor receptor-like
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRCC papillary renal cell carcinoma (translocation-associated)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRJ protein tyrosine phosphatase, receptor type, J
RAD54B RAD54 homolog B (S. cerevisiae)
RNF139 ring finger protein 139
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
TFE3 transcription factor binding to IGHM enhancer 3
TP53 tumor protein p53
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase