remoxipride-3124 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the remoxipride-3124 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ADAM20 ADAM metallopeptidase domain 20
AFF4 AF4/FMR2 family, member 4
AGFG2 ArfGAP with FG repeats 2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BCAS3 breast carcinoma amplified sequence 3
BMP7 bone morphogenetic protein 7
C10ORF10 chromosome 10 open reading frame 10
C1ORF61 chromosome 1 open reading frame 61
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAPN9 calpain 9
CD47 CD47 molecule
CD59 CD59 molecule, complement regulatory protein
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLMN calmin (calponin-like, transmembrane)
COL9A3 collagen, type IX, alpha 3
COLEC12 collectin sub-family member 12
CTC1 CTS telomere maintenance complex component 1
DCAF15 DDB1 and CUL4 associated factor 15
DCAF4 DDB1 and CUL4 associated factor 4
EDNRB endothelin receptor type B
EFNB3 ephrin-B3
ENG endoglin
ETAA1 Ewing tumor-associated antigen 1
EXOSC2 exosome component 2
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FADS3 fatty acid desaturase 3
FAM131A family with sequence similarity 131, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GATA4 GATA binding protein 4
GLG1 golgi glycoprotein 1
GNRHR gonadotropin-releasing hormone receptor
GOLGA2 golgin A2
GP5 glycoprotein V (platelet)
GPR153 G protein-coupled receptor 153
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HDAC11 histone deacetylase 11
HIST1H2AL histone cluster 1, H2al
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IFT27 intraflagellar transport 27
IL12RB1 interleukin 12 receptor, beta 1
IL17RC interleukin 17 receptor C
IL27RA interleukin 27 receptor, alpha
KEL Kell blood group, metallo-endopeptidase
LCMT2 leucine carboxyl methyltransferase 2
LOC730101 uncharacterized LOC730101
MAPK10 mitogen-activated protein kinase 10
MAST2 microtubule associated serine/threonine kinase 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYOZ3 myozenin 3
NMT2 N-myristoyltransferase 2
NOTCH3 notch 3
OMG oligodendrocyte myelin glycoprotein
OSBPL10 oxysterol binding protein-like 10
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH17 protocadherin 17
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIGR polymeric immunoglobulin receptor
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRPH2 peripherin 2 (retinal degeneration, slow)
PRR7 proline rich 7 (synaptic)
PTCRA pre T-cell antigen receptor alpha
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTK7 protein tyrosine kinase 7 (inactive)
PVR poliovirus receptor
RANBP3 RAN binding protein 3
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RPH3A rabphilin 3A
SCAND2P SCAN domain containing 2 pseudogene
SCN11A sodium channel, voltage gated, type XI alpha subunit
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLAMF8 SLAM family member 8
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SPATA2L spermatogenesis associated 2-like
SRCAP Snf2-related CREBBP activator protein
SRR serine racemase
TAGLN transgelin
THBS1 thrombospondin 1
TM6SF2 transmembrane 6 superfamily member 2
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNK2 tyrosine kinase, non-receptor, 2
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TSC2 tuberous sclerosis 2
UNC45A unc-45 homolog A (C. elegans)
VEGFB vascular endothelial growth factor B
YPEL1 yippee-like 1 (Drosophila)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADORA3 adenosine A3 receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKTIP AKT interacting protein
ARID5A AT rich interactive domain 5A (MRF1-like)
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BRD9 bromodomain containing 9
CBR3 carbonyl reductase 3
CCDC6 coiled-coil domain containing 6
CEP70 centrosomal protein 70kDa
CGREF1 cell growth regulator with EF-hand domain 1
CIDEC cell death-inducing DFFA-like effector c
CLCN5 chloride channel, voltage-sensitive 5
CRYL1 crystallin, lambda 1
CTSV cathepsin V
CXCL2 chemokine (C-X-C motif) ligand 2
CXORF56 chromosome X open reading frame 56
DCAF17 DDB1 and CUL4 associated factor 17
DEPDC5 DEP domain containing 5
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DOLK dolichol kinase
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXOSC1 exosome component 1
FAM118A family with sequence similarity 118, member A
FAM50B family with sequence similarity 50, member B
FGF9 fibroblast growth factor 9
FKBP9 FK506 binding protein 9, 63 kDa
GAA glucosidase, alpha; acid
GAMT guanidinoacetate N-methyltransferase
GLCE glucuronic acid epimerase
GMEB1 glucocorticoid modulatory element binding protein 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR19 G protein-coupled receptor 19
GPX2 glutathione peroxidase 2
HIST1H4D histone cluster 1, H4d
HOPX HOP homeobox
IDI2-AS1 IDI2 antisense RNA 1
IGLV1-44 immunoglobulin lambda variable 1-44
INF2 inverted formin, FH2 and WH2 domain containing
JAM2 junctional adhesion molecule 2
KDM5C lysine (K)-specific demethylase 5C
KIAA0754 KIAA0754
KIAA1107 KIAA1107
KIF24 kinesin family member 24
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KPTN kaptin (actin binding protein)
LOC100286895 cell division cycle 27 homolog pseudogene
LRRK1 leucine-rich repeat kinase 1
LZTR1 leucine-zipper-like transcription regulator 1
MAP1S microtubule-associated protein 1S
MB myoglobin
MCPH1 microcephalin 1
METTL16 methyltransferase like 16
MFSD6 major facilitator superfamily domain containing 6
MPZ myelin protein zero
NAG18 NAG18 mRNA
NAT6 N-acetyltransferase 6 (GCN5-related)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NINJ2 ninjurin 2
NOL10 nucleolar protein 10
NOL12 nucleolar protein 12
NPDC1 neural proliferation, differentiation and control, 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
POM121L2 POM121 transmembrane nucleoporin-like 2
RAB13 RAB13, member RAS oncogene family
RECQL4 RecQ protein-like 4
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOBTB1 Rho-related BTB domain containing 1
RNF126P1 ring finger protein 126 pseudogene 1
RUSC2 RUN and SH3 domain containing 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SH2B2 SH2B adaptor protein 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMR3A submaxillary gland androgen regulated protein 3A
SP140 SP140 nuclear body protein
SPATA20 spermatogenesis associated 20
SPON2 spondin 2, extracellular matrix protein
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STX5 syntaxin 5
TMEM53 transmembrane protein 53
TPM3 tropomyosin 3
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
USP20 ubiquitin specific peptidase 20
XAB2 XPA binding protein 2
ZBTB3 zinc finger and BTB domain containing 3
ZFHX3 zinc finger homeobox 3
ZNF286A zinc finger protein 286A
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747
ZNF787 zinc finger protein 787