relapsing-remitting multiple sclerosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A multiple sclerosis that is characterized by relapse (attacks of symptom flare-ups) followed by remission (periods of recovery). Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles. (Human Disease Ontology, DOID_2378)
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Genes

127 genes co-occuring with the disease relapsing-remitting multiple sclerosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
IFNB1 interferon, beta 1, fibroblast 3.22518
CD52 CD52 molecule 1.40395
CD4 CD4 molecule 1.29003
S1PR1 sphingosine-1-phosphate receptor 1 1.22475
MBP myelin basic protein 1.18755
MBTPS1 membrane-bound transcription factor peptidase, site 1 1.14517
MOG myelin oligodendrocyte glycoprotein 1.11477
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 1.0168
GHR growth hormone receptor 0.988535
FOXP3 forkhead box P3 0.9696
MX1 MX dynamin-like GTPase 1 0.93
AQP4 aquaporin 4 0.928759
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 0.917199
IL7R interleukin 7 receptor 0.890898
IL10 interleukin 10 0.862228
RGCC regulator of cell cycle 0.812232
IGHM immunoglobulin heavy constant mu 0.795411
OLA1 Obg-like ATPase 1 0.789262
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.74761
XCR1 chemokine (C motif) receptor 1 0.73746
PELO pelota homolog (Drosophila) 0.720865
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 0.720461
BDNF brain-derived neurotrophic factor 0.716425
CNTN1 contactin 1 0.702732
SCEL sciellin 0.695905
TMEM2 transmembrane protein 2 0.691495
ZFHX4 zinc finger homeobox 4 0.690293
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.67312
TBX21 T-box 21 0.671925
CLIP1 CAP-GLY domain containing linker protein 1 0.660404
NKRF NFKB repressing factor 0.650508
CXCR3 chemokine (C-X-C motif) receptor 3 0.618268
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 0.616703
IGBP1 immunoglobulin (CD79A) binding protein 1 0.605762
TPST1 tyrosylprotein sulfotransferase 1 0.596792
ICAM1 intercellular adhesion molecule 1 0.588222
HLA-G major histocompatibility complex, class I, G 0.578106
ZFAT zinc finger and AT hook domain containing 0.575383
CD40 CD40 molecule, TNF receptor superfamily member 5 0.572273
CXCL13 chemokine (C-X-C motif) ligand 13 0.569941
MMP9 matrix metallopeptidase 9 0.561781
IFNE interferon, epsilon 0.55518
IFNA1 interferon, alpha 1 0.552463
CD80 CD80 molecule 0.552463
S1PR3 sphingosine-1-phosphate receptor 3 0.544705
TNF tumor necrosis factor 0.542379
CXCL10 chemokine (C-X-C motif) ligand 10 0.534248
QPRT quinolinate phosphoribosyltransferase 0.525746
STAT1 signal transducer and activator of transcription 1, 91kDa 0.52536
TRAPPC10 trafficking protein particle complex 10 0.524974
ICAM3 intercellular adhesion molecule 3 0.515725
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.512648
IL2RA interleukin 2 receptor, alpha 0.491597
RORC RAR-related orphan receptor C 0.483985
CLDN11 claudin 11 0.474877
MIR17 microRNA 17 0.472225
RPL3 ribosomal protein L3 0.460129
IL1B interleukin 1, beta 0.456355
IL17A interleukin 17A 0.446558
FCMR Fc fragment of IgM receptor 0.43753
CD40LG CD40 ligand 0.42139
TIMP1 TIMP metallopeptidase inhibitor 1 0.413901
CCR1 chemokine (C-C motif) receptor 1 0.389281
CCL2 chemokine (C-C motif) ligand 2 0.387794
LRPPRC leucine-rich pentatricopeptide repeat containing 0.379997
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.379997
IL17F interleukin 17F 0.379256
APOD apolipoprotein D 0.374809
TTK TTK protein kinase 0.374438
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.371107
FFAR2 free fatty acid receptor 2 0.369997
KLK6 kallikrein-related peptidase 6 0.358183
COPA coatomer protein complex, subunit alpha 0.352659
SEPT1 septin 1 0.342006
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.339073
S1PR5 sphingosine-1-phosphate receptor 5 0.339073
SPP1 secreted phosphoprotein 1 0.333949
IL2 interleukin 2 0.328105
NEFH neurofilament, heavy polypeptide 0.320454
IL27 interleukin 27 0.316456
TRAF2 TNF receptor-associated factor 2 0.315729
TREM2 triggering receptor expressed on myeloid cells 2 0.313552
IL22 interleukin 22 0.312102
FASLG Fas ligand (TNF superfamily, member 6) 0.310652
MIRLET7D microRNA let-7d 0.306672
CD276 CD276 molecule 0.305587
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.295132
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.292975
CXCL11 chemokine (C-X-C motif) ligand 11 0.288668
AJAP1 adherens junctions associated protein 1 0.286519
CREM cAMP responsive element modulator 0.280439
SOCS3 suppressor of cytokine signaling 3 0.275089
NPAT nuclear protein, ataxia-telangiectasia locus 0.274376
GDF6 growth differentiation factor 6 0.274021
CD86 CD86 molecule 0.269753
CXCR5 chemokine (C-X-C motif) receptor 5 0.261952
ALB albumin 0.261952
CCL3 chemokine (C-C motif) ligand 3 0.25983
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.244345
CXCL12 chemokine (C-X-C motif) ligand 12 0.243295
CD1C CD1c molecule 0.242945
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.238752
LTB lymphotoxin beta (TNF superfamily, member 3) 0.230063
NOG noggin 0.228679
HLA-B major histocompatibility complex, class I, B 0.227297
PTRF polymerase I and transcript release factor 0.226607
STARD13 StAR-related lipid transfer (START) domain containing 13 0.226607
CXCR1 chemokine (C-X-C motif) receptor 1 0.222479
NOS2 nitric oxide synthase 2, inducible 0.21974
NGDN neuroguidin, EIF4E binding protein 0.212945
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.212608
LINGO1 leucine rich repeat and Ig domain containing 1 0.209918
HINT1 histidine triad nucleotide binding protein 1 0.208914
FADD Fas (TNFRSF6)-associated via death domain 0.199033
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.196459
DRD5 dopamine receptor D5 0.196139
CD19 CD19 molecule 0.193915
VCAM1 vascular cell adhesion molecule 1 0.18651
S1PR2 sphingosine-1-phosphate receptor 2 0.18591
CD69 CD69 molecule 0.177301
LEP leptin 0.171785
IRF1 interferon regulatory factor 1 0.171785
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.171036
CCL4 chemokine (C-C motif) ligand 4 0.168381
ADAR adenosine deaminase, RNA-specific 0.160387
CRYAB crystallin, alpha B 0.160021
NPTXR neuronal pentraxin receptor 0.159658