regulation of transmembrane receptor protein serine/threonine kinase signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. (Gene Ontology, GO_0090092)
External Link http://amigo.geneontology.org/amigo/term/GO:0090092
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Genes

204 genes participating in the regulation of transmembrane receptor protein serine/threonine kinase signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACVR1 activin A receptor, type I
ACVR1B activin A receptor, type IB
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ACVRL1 activin A receptor type II-like 1
ADAM17 ADAM metallopeptidase domain 17
ADAMTSL2 ADAMTS-like 2
ASPN asporin
AXIN1 axin 1
BAMBI BMP and activin membrane-bound inhibitor
BCL9 B-cell CLL/lymphoma 9
BCL9L B-cell CLL/lymphoma 9-like
BMP10 bone morphogenetic protein 10
BMP15 bone morphogenetic protein 15
BMP2 bone morphogenetic protein 2
BMP3 bone morphogenetic protein 3
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BMP8A bone morphogenetic protein 8a
BMP8B bone morphogenetic protein 8b
BMPER BMP binding endothelial regulator
BMPR1A bone morphogenetic protein receptor, type IA
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C10ORF54 chromosome 10 open reading frame 54
CAV2 caveolin 2
CAV3 caveolin 3
CD109 CD109 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CER1 cerberus 1, DAN family BMP antagonist
CHRD chordin
CHRDL1 chordin-like 1
CHRDL2 chordin-like 2
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIDEA cell death-inducing DFFA-like effector a
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRB2 crumbs family member 2
CSNK2B casein kinase 2, beta polypeptide
CYR61 cysteine-rich, angiogenic inducer, 61
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DACT1 dishevelled-binding antagonist of beta-catenin 1
DACT2 dishevelled-binding antagonist of beta-catenin 2
DAND5 DAN domain family member 5, BMP antagonist
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMRT1 doublesex and mab-3 related transcription factor 1
EID2 EP300 interacting inhibitor of differentiation 2
ENG endoglin
FAM89B family with sequence similarity 89, member B
FBN1 fibrillin 1
FBN2 fibrillin 2
FBXL15 F-box and leucine-rich repeat protein 15
FGF10 fibroblast growth factor 10
FGF9 fibroblast growth factor 9
FKBP1A FK506 binding protein 1A, 12kDa
FKBP8 FK506 binding protein 8, 38kDa
FLCN folliculin
FOXD1 forkhead box D1
FST follistatin
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD1 frizzled class receptor 1
GATA4 GATA binding protein 4
GDF1 growth differentiation factor 1
GDF10 growth differentiation factor 10
GDF11 growth differentiation factor 11
GDF15 growth differentiation factor 15
GDF2 growth differentiation factor 2
GDF3 growth differentiation factor 3
GDF5 growth differentiation factor 5
GDF6 growth differentiation factor 6
GDF7 growth differentiation factor 7
GDF9 growth differentiation factor 9
GIPC1 GIPC PDZ domain containing family, member 1
GLG1 golgi glycoprotein 1
GPC3 glypican 3
GREM1 gremlin 1, DAN family BMP antagonist
GREM2 gremlin 2, DAN family BMP antagonist
HES1 hes family bHLH transcription factor 1
HES5 hes family bHLH transcription factor 5
HFE hemochromatosis
HIPK2 homeodomain interacting protein kinase 2
HOXA13 homeobox A13
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTRA1 HtrA serine peptidase 1
HTRA3 HtrA serine peptidase 3
HTRA4 HtrA serine peptidase 4
IL17F interleukin 17F
ILK integrin-linked kinase
ING2 inhibitor of growth family, member 2
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INHBC inhibin, beta C
INHBE inhibin, beta E
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA8 integrin, alpha 8
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LEMD3 LEM domain containing 3
LRG1 leucine-rich alpha-2-glycoprotein 1
LTBP1 latent transforming growth factor beta binding protein 1
LTBP4 latent transforming growth factor beta binding protein 4
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MEN1 multiple endocrine neoplasia I
MSTN myostatin
MSX1 msh homeobox 1
MSX2 msh homeobox 2
MTMR4 myotubularin related protein 4
MYOCD myocardin
NANOG Nanog homeobox
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NKX2-1 NK2 homeobox 1
NODAL nodal growth differentiation factor
NOG noggin
NOTCH1 notch 1
NOTCH2 notch 2
NPNT nephronectin
NREP neuronal regeneration related protein
ONECUT1 one cut homeobox 1
ONECUT2 one cut homeobox 2
PARP1 poly (ADP-ribose) polymerase 1
PBLD phenazine biosynthesis-like protein domain containing
PCSK6 proprotein convertase subtilisin/kexin type 6
PDPK1 3-phosphoinositide dependent protein kinase 1
PEG10 paternally expressed 10
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRDM16 PR domain containing 16
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBPMS RNA binding protein with multiple splicing
RNF111 ring finger protein 111
RPS27A ribosomal protein S27a
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SHH sonic hedgehog
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SKOR1 SKI family transcriptional corepressor 1
SKOR2 SKI family transcriptional corepressor 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNW1 SNW domain containing 1
SNX25 sorting nexin 25
SNX6 sorting nexin 6
SOST sclerostin
SOSTDC1 sclerostin domain containing 1
SOX11 SRY (sex determining region Y)-box 11
SPG20 spastic paraplegia 20 (Troyer syndrome)
STK11 serine/threonine kinase 11
STRAP serine/threonine kinase receptor associated protein
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SULF1 sulfatase 1
SYNJ2BP synaptojanin 2 binding protein
TBX20 T-box 20
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TDGF1 teratocarcinoma-derived growth factor 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
TMPRSS6 transmembrane protease, serine 6
TOB1 transducer of ERBB2, 1
TP53 tumor protein p53
TRIM33 tripartite motif containing 33
TTK TTK protein kinase
TWSG1 twisted gastrulation BMP signaling modulator 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2O ubiquitin-conjugating enzyme E2O
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP15 ubiquitin specific peptidase 15
VASN vasorin
VWC2 von Willebrand factor C domain containing 2
VWC2L von Willebrand factor C domain containing protein 2-like
WNT1 wingless-type MMTV integration site family, member 1
WNT5A wingless-type MMTV integration site family, member 5A
WWTR1 WW domain containing transcription regulator 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO1 exportin 1
ZEB1 zinc finger E-box binding homeobox 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF423 zinc finger protein 423
ZNF703 zinc finger protein 703