regulation of t cell activation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of T cell activation. (Gene Ontology, GO_0050863)
External Link http://amigo.geneontology.org/amigo/term/GO:0050863
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Genes

246 genes participating in the regulation of t cell activation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADA adenosine deaminase
ADAM8 ADAM metallopeptidase domain 8
ADK adenosine kinase
AIF1 allograft inflammatory factor 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
BAD BCL2-associated agonist of cell death
BCL10 B-cell CLL/lymphoma 10
BCL6 B-cell CLL/lymphoma 6
BLM Bloom syndrome, RecQ helicase-like
BMP4 bone morphogenetic protein 4
BTLA B and T lymphocyte associated
BTN2A2 butyrophilin, subfamily 2, member A2
C10ORF54 chromosome 10 open reading frame 54
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CD1D CD1d molecule
CD2 CD2 molecule
CD209 CD209 molecule
CD24 CD24 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD300A CD300a molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD5 CD5 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD80 CD80 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CDC42 cell division cycle 42
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLC Charcot-Leyden crystal galectin
CLPTM1 cleft lip and palate associated transmembrane protein 1
CORO1A coronin, actin binding protein, 1A
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYLD cylindromatosis (turban tumor syndrome)
DHPS deoxyhypusine synthase
DLG1 discs, large homolog 1 (Drosophila)
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DPP4 dipeptidyl-peptidase 4
DTX1 deltex 1, E3 ubiquitin ligase
DUSP3 dual specificity phosphatase 3
EBI3 Epstein-Barr virus induced 3
EFNB1 ephrin-B1
EGR3 early growth response 3
ERBB2 erb-b2 receptor tyrosine kinase 2
FADD Fas (TNFRSF6)-associated via death domain
FOXJ1 forkhead box J1
FOXN1 forkhead box N1
FOXP3 forkhead box P3
FYN FYN proto-oncogene, Src family tyrosine kinase
GATA3 GATA binding protein 3
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GLMN glomulin, FKBP associated protein
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HES1 hes family bHLH transcription factor 1
HHLA2 HERV-H LTR-associating 2
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HLX H2.0-like homeobox
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
ICOS inducible T-cell co-stimulator
IDO1 indoleamine 2,3-dioxygenase 1
IFNA2 interferon, alpha 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IHH indian hedgehog
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL15 interleukin 15
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RL2 interleukin 1 receptor-like 2
IL2 interleukin 2
IL20RB interleukin 20 receptor beta
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL36B interleukin 36, beta
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
IRF1 interferon regulatory factor 1
IRF4 interferon regulatory factor 4
ITCH itchy E3 ubiquitin protein ligase
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
JAK3 Janus kinase 3
LAG3 lymphocyte-activation gene 3
LAT linker for activation of T cells
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LRRC32 leucine rich repeat containing 32
LYN LYN proto-oncogene, Src family tyrosine kinase
MALT1 MALT1 paracaspase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYB v-myb avian myeloblastosis viral oncogene homolog
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKAP1L NCK-associated protein 1-like
NDFIP1 Nedd4 family interacting protein 1
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NKAP NFKB activating protein
NOD2 nucleotide-binding oligomerization domain containing 2
NRARP NOTCH-regulated ankyrin repeat protein
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAWR PRKC, apoptosis, WT1, regulator
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDE5A phosphodiesterase 5A, cGMP-specific
PDPK1 3-phosphoinositide dependent protein kinase 1
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PNP purine nucleoside phosphorylase
PRELID1 PRELI domain containing 1
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRNP prion protein
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAG1 recombination activating gene 1
RARA retinoic acid receptor, alpha
RC3H1 ring finger and CCCH-type domains 1
RICTOR RPTOR independent companion of MTOR, complex 2
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RORC RAR-related orphan receptor C
SART1 squamous cell carcinoma antigen recognized by T cells
SASH3 SAM and SH3 domain containing 3
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SFTPD surfactant protein D
SHH sonic hedgehog
SIRPG signal-regulatory protein gamma
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC46A2 solute carrier family 46, member 2
SOCS5 suppressor of cytokine signaling 5
SOCS6 suppressor of cytokine signaling 6
SOD1 superoxide dismutase 1, soluble
SOX13 SRY (sex determining region Y)-box 13
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTA1 spectrin, alpha, erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase
TESPA1 thymocyte expressed, positive selection associated 1
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THY1 Thy-1 cell surface antigen
TIGIT T cell immunoreceptor with Ig and ITIM domains
TMIGD2 transmembrane and immunoglobulin domain containing 2
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
VAV1 vav 1 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VNN1 vanin 1
VSIG4 V-set and immunoglobulin domain containing 4
VTCN1 V-set domain containing T cell activation inhibitor 1
XBP1 X-box binding protein 1
XCL1 chemokine (C motif) ligand 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1
ZBTB16 zinc finger and BTB domain containing 16
ZC3H8 zinc finger CCCH-type containing 8
ZEB1 zinc finger E-box binding homeobox 1
ZNHIT1 zinc finger, HIT-type containing 1
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4