regulation of protein serine/threonine kinase activity Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity. (Gene Ontology, GO_0071900)
External Link http://amigo.geneontology.org/amigo/term/GO:0071900
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Genes

425 genes participating in the regulation of protein serine/threonine kinase activity biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACSL1 acyl-CoA synthetase long-chain family member 1
ADAM17 ADAM metallopeptidase domain 17
ADAM8 ADAM metallopeptidase domain 8
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2B adenosine A2b receptor
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIDA axin interactor, dorsalization associated
AJUBA ajuba LIM protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
APC adenomatous polyposis coli
APOE apolipoprotein E
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AVPI1 arginine vasopressin-induced 1
AXIN1 axin 1
BCCIP BRCA2 and CDKN1A interacting protein
BIRC7 baculoviral IAP repeat containing 7
BLM Bloom syndrome, RecQ helicase-like
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
C1QTNF2 C1q and tumor necrosis factor related protein 2
C5 complement component 5
C5AR1 complement component 5a receptor 1
CAB39 calcium binding protein 39
CAMK1 calcium/calmodulin-dependent protein kinase I
CARD10 caspase recruitment domain family, member 10
CARD14 caspase recruitment domain family, member 14
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CCL19 chemokine (C-C motif) ligand 19
CCNA1 cyclin A1
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNB2 cyclin B2
CCNB3 cyclin B3
CCNC cyclin C
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE2 cyclin E2
CCNG1 cyclin G1
CCNH cyclin H
CCNK cyclin K
CCNL1 cyclin L1
CCNL2 cyclin L2
CCNT1 cyclin T1
CCNT2 cyclin T2
CCNY cyclin Y
CCNYL1 cyclin Y-like 1
CD24 CD24 molecule
CD300A CD300a molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD81 CD81 molecule
CDC25A cell division cycle 25A
CDC25C cell division cycle 25C
CDC37 cell division cycle 37
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CDK12 cyclin-dependent kinase 12
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39)
CDK5RAP1 CDK5 regulatory subunit associated protein 1
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDK7 cyclin-dependent kinase 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDKN3 cyclin-dependent kinase inhibitor 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CIB1 calcium and integrin binding 1 (calmyrin)
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COPS8 COP9 signalosome subunit 8
CSF1R colony stimulating factor 1 receptor
CSK c-src tyrosine kinase
CSPG4 chondroitin sulfate proteoglycan 4
CXCR4 chemokine (C-X-C motif) receptor 4
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAB2IP DAB2 interacting protein
DAXX death-domain associated protein
DBNL drebrin-like
DIRAS1 DIRAS family, GTP-binding RAS-like 1
DIRAS2 DIRAS family, GTP-binding RAS-like 2
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DRD4 dopamine receptor D4
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP14 dual specificity phosphatase 14
DUSP16 dual specificity phosphatase 16
DUSP18 dual specificity phosphatase 18
DUSP19 dual specificity phosphatase 19
DUSP2 dual specificity phosphatase 2
DUSP21 dual specificity phosphatase 21
DUSP22 dual specificity phosphatase 22
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
EDN1 endothelin 1
EDN3 endothelin 3
EFNA1 ephrin-A1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
EPGN epithelial mitogen
EPHA4 EPH receptor A4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC6 excision repair cross-complementation group 6
EREG epiregulin
ERP29 endoplasmic reticulum protein 29
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM58A family with sequence similarity 58, member A
FBXO7 F-box protein 7
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF18 fibroblast growth factor 18
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FPR1 formyl peptide receptor 1
FRS2 fibroblast growth factor receptor substrate 2
FZD10 frizzled class receptor 10
FZD4 frizzled class receptor 4
FZD5 frizzled class receptor 5
FZD8 frizzled class receptor 8
GAB1 GRB2-associated binding protein 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GBA glucosidase, beta, acid
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPS1 G protein pathway suppressor 1
GPS2 G protein pathway suppressor 2
GRM1 glutamate receptor, metabotropic 1
GRM4 glutamate receptor, metabotropic 4
GRM5 glutamate receptor, metabotropic 5
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTPBP4 GTP binding protein 4
H2AFY H2A histone family, member Y
HACD3 3-hydroxyacyl-CoA dehydratase 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HEXIM1 hexamethylene bis-acetamide inducible 1
HEXIM2 hexamethylene bis-acetamide inducible 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HHEX hematopoietically expressed homeobox
HIPK3 homeodomain interacting protein kinase 3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA2 heat shock 70kDa protein 2
HSPB1 heat shock 27kDa protein 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
IGF2 insulin-like growth factor 2
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
ILK integrin-linked kinase
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1
INPP5K inositol polyphosphate-5-phosphatase K
INSR insulin receptor
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP3 IQ motif containing GTPase activating protein 3
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
ITGA1 integrin, alpha 1
KAT2B K(lysine) acetyltransferase 2B
KIAA1804 mixed lineage kinase 4
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LAX1 lymphocyte transmembrane adaptor 1
LPAR1 lysophosphatidic acid receptor 1
LPAR2 lysophosphatidic acid receptor 2
LPAR3 lysophosphatidic acid receptor 3
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LRRK2 leucine-rich repeat kinase 2
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
MADD MAP-kinase activating death domain
MAGED1 melanoma antigen family D1
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MALT1 MALT1 paracaspase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MBIP MAP3K12 binding inhibitory protein 1
MDFI MyoD family inhibitor
MDFIC MyoD family inhibitor domain containing
MEF2C myocyte enhancer factor 2C
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MNAT1 MNAT CDK-activating kinase assembly factor 1
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MST1R macrophage stimulating 1 receptor
MUC20 mucin 20, cell surface associated
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYOCD myocardin
NEK1 NIMA-related kinase 1
NEK10 NIMA-related kinase 10
NF1 neurofibromin 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOX4 NADPH oxidase 4
NPFFR2 neuropeptide FF receptor 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NTF3 neurotrophin 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUP62 nucleoporin 62kDa
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAQR3 progestin and adipoQ receptor family member III
PARP16 poly (ADP-ribose) polymerase family, member 16
PDCD10 programmed cell death 10
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE5A phosphodiesterase 5A, cGMP-specific
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PKN1 protein kinase N1
PLA2G1B phospholipase A2, group IB (pancreas)
PLCE1 phospholipase C, epsilon 1
PLK1 polo-like kinase 1
PPEF2 protein phosphatase, EF-hand calcium binding domain 2
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PROK1 prokineticin 1
PROK2 prokineticin 2
PROX1 prospero homeobox 1
PSEN1 presenilin 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSRC1 proline/serine-rich coiled-coil 1
PTEN phosphatase and tensin homolog
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRJ protein tyrosine phosphatase, receptor type, J
PXN paxillin
PYCARD PYD and CARD domain containing
RALB v-ral simian leukemia viral oncogene homolog B
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RGCC regulator of cell cycle
RGS14 regulator of G-protein signaling 14
RGS2 regulator of G-protein signaling 2
RGS3 regulator of G-protein signaling 3
RGS4 regulator of G-protein signaling 4
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RPS27A ribosomal protein S27a
RPTOR regulatory associated protein of MTOR, complex 1
S100A12 S100 calcium binding protein A12
S1PR2 sphingosine-1-phosphate receptor 2
SAA1 serum amyloid A1
SASH1 SAM and SH3 domain containing 1
SBK2 SH3 domain binding kinase family, member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERTAD1 SERTA domain containing 1
SESN2 sestrin 2
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP5 secreted frizzled-related protein 5
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SIRT1 sirtuin 1
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNF8 SNF8, ESCRT-II complex subunit
SOD1 superoxide dismutase 1, soluble
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPAG9 sperm associated antigen 9
SPDYA speedy/RINGO cell cycle regulator family member A
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRED3 sprouty-related, EVH1 domain containing 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STIL SCL/TAL1 interrupting locus
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STK4 serine/threonine kinase 4
STRADA STE20-related kinase adaptor alpha
SYK spleen tyrosine kinase
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TAOK3 TAO kinase 3
TDGF1 teratocarcinoma-derived growth factor 1
TENM1 teneurin transmembrane protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
THBS1 thrombospondin 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNXB tenascin XB
TP73 tumor protein p73
TPD52L1 tumor protein D52-like 1
TRAF2 TNF receptor-associated factor 2
TRAF4 TNF receptor-associated factor 4
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TSC2 tuberous sclerosis 2
TSG101 tumor susceptibility 101
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VANGL2 VANGL planar cell polarity protein 2
VEGFA vascular endothelial growth factor A
WEE2 WEE1 homolog 2 (S. pombe)
WNT5A wingless-type MMTV integration site family, member 5A
WNT7B wingless-type MMTV integration site family, member 7B
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZEB2 zinc finger E-box binding homeobox 2
ZFP91 ZFP91 zinc finger protein
ZNF675 zinc finger protein 675