regulation of protein secretion Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. (Gene Ontology, GO_0050708)
External Link http://amigo.geneontology.org/amigo/term/GO:0050708
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Genes

338 genes participating in the regulation of protein secretion biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AACS acetoacetyl-CoA synthetase
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACHE acetylcholinesterase (Yt blood group)
ACVR1C activin A receptor, type IC
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADRA2A adrenoceptor alpha 2A
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
AGTR2 angiotensin II receptor, type 2
AIM2 absent in melanoma 2
AKAP5 A kinase (PRKA) anchor protein 5
ALOX15B arachidonate 15-lipoxygenase, type B
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANXA1 annexin A1
ANXA4 annexin A4
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
ARFIP1 ADP-ribosylation factor interacting protein 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB1 arrestin, beta 1
ATG5 autophagy related 5
BAD BCL2-associated agonist of cell death
BANK1 B-cell scaffold protein with ankyrin repeats 1
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP6 bone morphogenetic protein 6
BMP8A bone morphogenetic protein 8a
BRSK2 BR serine/threonine kinase 2
BTN2A2 butyrophilin, subfamily 2, member A2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2CD2L C2CD2-like
C5 complement component 5
C5AR2 complement component 5a receptor 2
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CADM1 cell adhesion molecule 1
CAPN10 calpain 10
CARD8 caspase recruitment domain family, member 8
CARTPT CART prepropeptide
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCL19 chemokine (C-C motif) ligand 19
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCR7 chemokine (C-C motif) receptor 7
CD14 CD14 molecule
CD2 CD2 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD58 CD58 molecule
CDK16 cyclin-dependent kinase 16
CHIA chitinase, acidic
CHRM3 cholinergic receptor, muscarinic 3
CIDEA cell death-inducing DFFA-like effector a
CLEC4E C-type lectin domain family 4, member E
CLEC5A C-type lectin domain family 5, member A
CLEC6A C-type lectin domain family 6, member A
CLEC9A C-type lectin domain family 9, member A
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CPT1A carnitine palmitoyltransferase 1A (liver)
CRH corticotropin releasing hormone
CRP C-reactive protein, pentraxin-related
CRTAM cytotoxic and regulatory T cell molecule
CSF1R colony stimulating factor 1 receptor
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNM1L dynamin 1-like
DOC2B double C2-like domains, beta
DPH3 diphthamide biosynthesis 3
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
EFNA5 ephrin-A5
ENSA endosulfine alpha
EPHA5 EPH receptor A5
ERP29 endoplasmic reticulum protein 29
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM132A family with sequence similarity 132, member A
FAM3D family with sequence similarity 3, member D
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FFAR1 free fatty acid receptor 1
FFAR2 free fatty acid receptor 2
FFAR4 free fatty acid receptor 4
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FGR FGR proto-oncogene, Src family tyrosine kinase
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXA2 forkhead box A2
FOXP1 forkhead box P1
FOXP3 forkhead box P3
G6PC2 glucose-6-phosphatase, catalytic, 2
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GCG glucagon
GCK glucokinase (hexokinase 4)
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GIP gastric inhibitory polypeptide
GIPR gastric inhibitory polypeptide receptor
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GLMN glomulin, FKBP associated protein
GLP1R glucagon-like peptide 1 receptor
GLUD1 glutamate dehydrogenase 1
GLUL glutamate-ammonia ligase
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GOLPH3L golgi phosphoprotein 3-like
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPER1 G protein-coupled estrogen receptor 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR68 G protein-coupled receptor 68
HADH hydroxyacyl-CoA dehydrogenase
HCAR2 hydroxycarboxylic acid receptor 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-E major histocompatibility complex, class I, E
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HNF4A hepatocyte nuclear factor 4, alpha
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
IFNA2 interferon, alpha 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL2 interleukin 2
IL26 interleukin 26
IL33 interleukin 33
IL36RN interleukin 36 receptor antagonist
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
INHBB inhibin, beta B
INS insulin
IQGAP1 IQ motif containing GTPase activating protein 1
IRF3 interferon regulatory factor 3
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ISL1 ISL LIM homeobox 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAK2 Janus kinase 2
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KRT20 keratin 20, type I
LEP leptin
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LRP5 low density lipoprotein receptor-related protein 5
LRRC32 leucine rich repeat containing 32
LYN LYN proto-oncogene, Src family tyrosine kinase
MARCKS myristoylated alanine-rich protein kinase C substrate
MCU mitochondrial calcium uniporter
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MIDN midnolin
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MTNR1B melatonin receptor 1B
MYO18A myosin XVIIIA
MYRIP myosin VIIA and Rab interacting protein
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
NEUROD1 neuronal differentiation 1
NKX6-1 NK6 homeobox 1
NLGN2 neuroligin 2
NLRP1 NLR family, pyrin domain containing 1
NLRP10 NLR family, pyrin domain containing 10
NLRP12 NLR family, pyrin domain containing 12
NLRP2 NLR family, pyrin domain containing 2
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NPFF neuropeptide FF-amide peptide precursor
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRXN1 neurexin 1
OPRM1 opioid receptor, mu 1
OR51E2 olfactory receptor, family 51, subfamily E, member 2
OXCT1 3-oxoacid CoA transferase 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P3H1 prolyl 3-hydroxylase 1
PAEP progestagen-associated endometrial protein
PANX1 pannexin 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE8B phosphodiesterase 8B
PDX1 pancreatic and duodenal homeobox 1
PER2 period circadian clock 2
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PFKL phosphofructokinase, liver
PFKM phosphofructokinase, muscle
PHPT1 phosphohistidine phosphatase 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PPARD peroxisome proliferator-activated receptor delta
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPID peptidylprolyl isomerase D
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PRKCZ protein kinase C, zeta
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PYCARD PYD and CARD domain containing
PYDC1 PYD (pyrin domain) containing 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAP1A RAP1A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBP4 retinol binding protein 4, plasma
REST RE1-silencing transcription factor
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RFX6 regulatory factor X, 6
RGCC regulator of cell cycle
RHBDD3 rhomboid domain containing 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RPH3AL rabphilin 3A-like (without C2 domains)
RSAD2 radical S-adenosyl methionine domain containing 2
SAA1 serum amyloid A1
SCAMP5 secretory carrier membrane protein 5
SEC11A SEC11 homolog A (S. cerevisiae)
SEC11C SEC11 homolog C (S. cerevisiae)
SEC24A SEC24 family member A
SERGEF secretion regulating guanine nucleotide exchange factor
SERP1 stress-associated endoplasmic reticulum protein 1
SFRP1 secreted frizzled-related protein 1
SIDT2 SID1 transmembrane family, member 2
SIRT4 sirtuin 4
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAP25 synaptosomal-associated protein, 25kDa
SOX4 SRY (sex determining region Y)-box 4
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae)
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SRGN serglycin
SRI sorcin
SSC5D scavenger receptor cysteine rich family, 5 domains
SSTR3 somatostatin receptor 3
SSTR5 somatostatin receptor 5
STX1A syntaxin 1A (brain)
STX4 syntaxin 4
STXBP1 syntaxin binding protein 1
STXBP4 syntaxin binding protein 4
STXBP5L syntaxin binding protein 5-like
SYBU syntabulin (syntaxin-interacting)
SYK spleen tyrosine kinase
SYT5 synaptotagmin V
SYT7 synaptotagmin VII
SYT9 synaptotagmin IX
SYTL4 synaptotagmin-like 4
TARDBP TAR DNA binding protein
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEK TEK tyrosine kinase, endothelial
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMEM27 transmembrane protein 27
TNF tumor necrosis factor
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRH thyrotropin-releasing hormone
TRIM16 tripartite motif containing 16
TRIM27 tripartite motif containing 27
TWIST1 twist family bHLH transcription factor 1
UCN3 urocortin 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2
UTS2 urotensin 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAMP3 vesicle-associated membrane protein 3
VEGFC vascular endothelial growth factor C
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT5A wingless-type MMTV integration site family, member 5A
XBP1 X-box binding protein 1
ZNF384 zinc finger protein 384