regulation of protein catabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. (Gene Ontology, GO_0042176)
External Link http://amigo.geneontology.org/amigo/term/GO:0042176
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Genes

378 genes participating in the regulation of protein catabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADRA2A adrenoceptor alpha 2A
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
ANXA2 annexin A2
APC adenomatous polyposis coli
APOE apolipoprotein E
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASB9 ankyrin repeat and SOCS box containing 9
ATG4B autophagy related 4B, cysteine peptidase
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
ATPIF1 ATPase inhibitory factor 1
ATRAID all-trans retinoic acid-induced differentiation factor
AURKA aurora kinase A
AXIN1 axin 1
AZIN1 antizyme inhibitor 1
AZIN2 antizyme inhibitor 2
BAG5 BCL2-associated athanogene 5
BAG6 BCL2-associated athanogene 6
BANP BTG3 associated nuclear protein
BARD1 BRCA1 associated RING domain 1
BBS7 Bardet-Biedl syndrome 7
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
CAV3 caveolin 3
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCAR2 cell cycle and apoptosis regulator 2
CCDC22 coiled-coil domain containing 22
CCNB1 cyclin B1
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC42 cell division cycle 42
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CHEK2 checkpoint kinase 2
CLU clusterin
COMMD1 copper metabolism (Murr1) domain containing 1
CSNK1D casein kinase 1, delta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CST3 cystatin C
CTSC cathepsin C
CUL1 cullin 1
CUL3 cullin 3
CUL4B cullin 4B
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAB2IP DAB2 interacting protein
DACT1 dishevelled-binding antagonist of beta-catenin 1
DDRGK1 DDRGK domain containing 1
DEDD death effector domain containing
DISC1 disrupted in schizophrenia 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DTHD1 death domain containing 1
DVL1 dishevelled segment polarity protein 1
DYX1C1 dyslexia susceptibility 1 candidate 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FAF1 Fas (TNFRSF6) associated factor 1
FBXL5 F-box and leucine-rich repeat protein 5
FBXO22 F-box protein 22
FBXO43 F-box protein 43
FBXO5 F-box protein 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHIT fragile histidine triad
FLNA filamin A, alpha
FMN2 formin 2
FOXO1 forkhead box O1
FURIN furin (paired basic amino acid cleaving enzyme)
FYN FYN proto-oncogene, Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABARAPL2 GABA(A) receptor-associated protein-like 2
GBA glucosidase, beta, acid
GCLC glutamate-cysteine ligase, catalytic subunit
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GIPC1 GIPC PDZ domain containing family, member 1
GJA1 gap junction protein, alpha 1, 43kDa
GLMN glomulin, FKBP associated protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPC3 glypican 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPX1 glutathione peroxidase 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HFE hemochromatosis
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IER3 immediate early response 3
IFNG interferon, gamma
IL10 interleukin 10
IL1B interleukin 1, beta
IL33 interleukin 33
INS insulin
IRAK3 interleukin-1 receptor-associated kinase 3
ITCH itchy E3 ubiquitin protein ligase
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KEAP1 kelch-like ECH-associated protein 1
KLHL22 kelch-like family member 22
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRRK2 leucine-rich repeat kinase 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAPK15 mitogen-activated protein kinase 15
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase
MYLIP myosin regulatory light chain interacting protein
N4BP1 NEDD4 binding protein 1
NDFIP1 Nedd4 family interacting protein 1
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEK6 NIMA-related kinase 6
NELL1 NEL-like 1 (chicken)
NKD1 naked cuticle homolog 1 (Drosophila)
NKD2 naked cuticle homolog 2 (Drosophila)
NOS2 nitric oxide synthase 2, inducible
NRD1 nardilysin (N-arginine dibasic convertase)
NRG1 neuregulin 1
NSF N-ethylmaleimide-sensitive factor
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NUB1 negative regulator of ubiquitin-like proteins 1
OAZ1 ornithine decarboxylase antizyme 1
OAZ2 ornithine decarboxylase antizyme 2
OAZ3 ornithine decarboxylase antizyme 3
ODC1 ornithine decarboxylase 1
OPHN1 oligophrenin 1
OSBPL7 oxysterol binding protein-like 7
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PBK PDZ binding kinase
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCL3 phosducin-like 3
PIAS1 protein inhibitor of activated STAT, 1
PINK1 PTEN induced putative kinase 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRICKLE1 prickle homolog 1 (Drosophila)
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCG protein kinase C, gamma
PSEN1 presenilin 1
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN3 protein tyrosine phosphatase, non-receptor type 3
RAB7A RAB7A, member RAS oncogene family
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RB1 retinoblastoma 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHBDD3 rhomboid domain containing 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIC1 RAB6A GEF complex partner 1
RNF139 ring finger protein 139
RNF180 ring finger protein 180
RPS27A ribosomal protein S27a
SAMD9L sterile alpha motif domain containing 9-like
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SENP1 SUMO1/sentrin specific peptidase 1
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SF3B3 splicing factor 3b, subunit 3, 130kDa
SH3D19 SH3 domain containing 19
SHH sonic hedgehog
SIRT2 sirtuin 2
SKP1 S-phase kinase-associated protein 1
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMC5 structural maintenance of chromosomes 5
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNF8 SNF8, ESCRT-II complex subunit
SNX1 sorting nexin 1
SNX12 sorting nexin 12
SNX3 sorting nexin 3
SNX33 sorting nexin 33
SNX9 sorting nexin 9
SOCS4 suppressor of cytokine signaling 4
SOCS5 suppressor of cytokine signaling 5
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX17 SRY (sex determining region Y)-box 17
SOX9 SRY (sex determining region Y)-box 9
STIL SCL/TAL1 interrupting locus
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX5 syntaxin 5
SUFU suppressor of fused homolog (Drosophila)
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
SVIP small VCP/p97-interacting protein
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TEX14 testis expressed 14
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLK2 tousled-like kinase 2
TMF1 TATA element modulatory factor 1
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TPR translocated promoter region, nuclear basket protein
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TRIM32 tripartite motif containing 32
TRIM39 tripartite motif containing 39
TRIM40 tripartite motif containing 40
TRIM67 tripartite motif containing 67
TTK TTK protein kinase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2K ubiquitin-conjugating enzyme E2K
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE3A ubiquitin protein ligase E3A
UBQLN4 ubiquilin 4
UBXN1 UBX domain protein 1
UBXN2A UBX domain protein 2A
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UFL1 UFM1-specific ligase 1
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2
USP1 ubiquitin specific peptidase 1
USP10 ubiquitin specific peptidase 10
USP11 ubiquitin specific peptidase 11
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP15 ubiquitin specific peptidase 15
USP16 ubiquitin specific peptidase 16
USP17L10 ubiquitin specific peptidase 17-like family member 10
USP17L11 ubiquitin specific peptidase 17-like family member 11
USP17L12 ubiquitin specific peptidase 17-like family member 12
USP17L13 ubiquitin specific peptidase 17-like family member 13
USP17L17 ubiquitin specific peptidase 17-like family member 17
USP17L18 ubiquitin specific peptidase 17-like family member 18
USP17L19 ubiquitin specific peptidase 17-like family member 19
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP17L20 ubiquitin specific peptidase 17-like family member 20
USP17L21 ubiquitin specific peptidase 17-like family member 21
USP17L22 ubiquitin specific peptidase 17-like family member 22
USP17L5 ubiquitin specific peptidase 17-like family member 5
USP18 ubiquitin specific peptidase 18
USP19 ubiquitin specific peptidase 19
USP2 ubiquitin specific peptidase 2
USP20 ubiquitin specific peptidase 20
USP21 ubiquitin specific peptidase 21
USP22 ubiquitin specific peptidase 22
USP24 ubiquitin specific peptidase 24
USP25 ubiquitin specific peptidase 25
USP26 ubiquitin specific peptidase 26
USP28 ubiquitin specific peptidase 28
USP29 ubiquitin specific peptidase 29
USP3 ubiquitin specific peptidase 3
USP30 ubiquitin specific peptidase 30
USP31 ubiquitin specific peptidase 31
USP32 ubiquitin specific peptidase 32
USP33 ubiquitin specific peptidase 33
USP34 ubiquitin specific peptidase 34
USP35 ubiquitin specific peptidase 35
USP36 ubiquitin specific peptidase 36
USP37 ubiquitin specific peptidase 37
USP38 ubiquitin specific peptidase 38
USP4 ubiquitin specific peptidase 4 (proto-oncogene)
USP40 ubiquitin specific peptidase 40
USP42 ubiquitin specific peptidase 42
USP43 ubiquitin specific peptidase 43
USP44 ubiquitin specific peptidase 44
USP45 ubiquitin specific peptidase 45
USP47 ubiquitin specific peptidase 47
USP48 ubiquitin specific peptidase 48
USP49 ubiquitin specific peptidase 49
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USP51 ubiquitin specific peptidase 51
USP6 ubiquitin specific peptidase 6
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
USP9Y ubiquitin specific peptidase 9, Y-linked
VCP valosin containing protein
VIP vasoactive intestinal peptide
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
WAC WW domain containing adaptor with coiled-coil
WNT1 wingless-type MMTV integration site family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
WNT5A wingless-type MMTV integration site family, member 5A
XBP1 X-box binding protein 1
XPO1 exportin 1
ZFAND2A zinc finger, AN1-type domain 2A
ZNF207 zinc finger protein 207