regulation of proteasomal ubiquitin-dependent protein catabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome. (Gene Ontology, GO_0032434)
External Link http://amigo.geneontology.org/amigo/term/GO:0032434
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Genes

124 genes participating in the regulation of proteasomal ubiquitin-dependent protein catabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
APC adenomatous polyposis coli
ARAF A-Raf proto-oncogene, serine/threonine kinase
ATM ATM serine/threonine kinase
ATRAID all-trans retinoic acid-induced differentiation factor
AURKA aurora kinase A
AXIN1 axin 1
BAG5 BCL2-associated athanogene 5
BAG6 BCL2-associated athanogene 6
BBS7 Bardet-Biedl syndrome 7
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CCAR2 cell cycle and apoptosis regulator 2
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC6 cell division cycle 6
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CLU clusterin
COMMD1 copper metabolism (Murr1) domain containing 1
CSNK1D casein kinase 1, delta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CUL3 cullin 3
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAB2IP DAB2 interacting protein
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DTHD1 death domain containing 1
DVL1 dishevelled segment polarity protein 1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FBXO22 F-box protein 22
FBXO5 F-box protein 5
FHIT fragile histidine triad
GCLC glutamate-cysteine ligase, catalytic subunit
GIPC1 GIPC PDZ domain containing family, member 1
GLMN glomulin, FKBP associated protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GSK3B glycogen synthase kinase 3 beta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HFE hemochromatosis
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IL33 interleukin 33
KEAP1 kelch-like ECH-associated protein 1
KLHL22 kelch-like family member 22
LRRK2 leucine-rich repeat kinase 2
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
N4BP1 NEDD4 binding protein 1
NEK6 NIMA-related kinase 6
NELL1 NEL-like 1 (chicken)
NKD2 naked cuticle homolog 2 (Drosophila)
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NUB1 negative regulator of ubiquitin-like proteins 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PBK PDZ binding kinase
PIAS1 protein inhibitor of activated STAT, 1
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PRICKLE1 prickle homolog 1 (Drosophila)
PSEN1 presenilin 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMG2 proteasome (prosome, macropain) assembly chaperone 2
PTEN phosphatase and tensin homolog
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RB1 retinoblastoma 1
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RNF180 ring finger protein 180
SENP1 SUMO1/sentrin specific peptidase 1
SHH sonic hedgehog
SIRT2 sirtuin 2
SMAD7 SMAD family member 7
SMC5 structural maintenance of chromosomes 5
SOCS4 suppressor of cytokine signaling 4
SOCS5 suppressor of cytokine signaling 5
STIL SCL/TAL1 interrupting locus
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SVIP small VCP/p97-interacting protein
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TEX14 testis expressed 14
TLK2 tousled-like kinase 2
TPR translocated promoter region, nuclear basket protein
TRIB1 tribbles pseudokinase 1
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TTK TTK protein kinase
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2K ubiquitin-conjugating enzyme E2K
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBQLN4 ubiquilin 4
UBXN1 UBX domain protein 1
UFL1 UFM1-specific ligase 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP44 ubiquitin specific peptidase 44
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VCP valosin containing protein
WAC WW domain containing adaptor with coiled-coil
WNT10B wingless-type MMTV integration site family, member 10B
ZFAND2A zinc finger, AN1-type domain 2A
ZNF207 zinc finger protein 207