regulation of peptidase activity Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. (Gene Ontology, GO_0052547)
External Link http://amigo.geneontology.org/amigo/term/GO:0052547
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Genes

362 genes participating in the regulation of peptidase activity biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACER2 alkaline ceramidase 2
ACVR1C activin A receptor, type IC
ADRM1 adhesion regulating molecule 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSG alpha-2-HS-glycoprotein
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIM2 absent in melanoma 2
AKIRIN2 akirin 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX12 arachidonate 12-lipoxygenase
AMBP alpha-1-microglobulin/bikunin precursor
ANOS1 anosmin 1
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
APAF1 apoptotic peptidase activating factor 1
APLP2 amyloid beta (A4) precursor-like protein 2
APOPT1 apoptogenic 1, mitochondrial
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASPH aspartate beta-hydroxylase
AVP arginine vasopressin
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCAP31 B-cell receptor-associated protein 31
BCL10 B-cell CLL/lymphoma 10
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L12 BCL2-like 12 (proline rich)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BIRC6 baculoviral IAP repeat containing 6
BIRC7 baculoviral IAP repeat containing 7
BIRC8 baculoviral IAP repeat containing 8
BOK BCL2-related ovarian killer
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
C5 complement component 5
CARD16 caspase recruitment domain family, member 16
CARD17 caspase recruitment domain family, member 17
CARD18 caspase recruitment domain family, member 18
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CCK cholecystokinin
CD109 CD109 molecule
CD27 CD27 molecule
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFLAR CASP8 and FADD-like apoptosis regulator
CIDEB cell death-inducing DFFA-like effector b
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COL28A1 collagen, type XXVIII, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL6A3 collagen, type VI, alpha 3
COL7A1 collagen, type VII, alpha 1
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRB2 crumbs family member 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRYAB crystallin, alpha B
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CST1 cystatin SN
CST11 cystatin 11
CST2 cystatin SA
CST3 cystatin C
CST4 cystatin S
CST5 cystatin D
CST6 cystatin E/M
CST7 cystatin F (leukocystatin)
CST8 cystatin 8 (cystatin-related epididymal specific)
CST9 cystatin 9 (testatin)
CST9L cystatin 9-like
CSTA cystatin A (stefin A)
CSTB cystatin B (stefin B)
CSTL1 cystatin-like 1
CTGF connective tissue growth factor
CTSH cathepsin H
CYCS cytochrome c, somatic
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYR61 cysteine-rich, angiogenic inducer, 61
DAP death-associated protein
DAPK1 death-associated protein kinase 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DHCR24 24-dehydrocholesterol reductase
DIABLO diablo, IAP-binding mitochondrial protein
DLC1 DLC1 Rho GTPase activating protein
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPEP1 dipeptidase 1 (renal)
ECM1 extracellular matrix protein 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EPHA7 EPH receptor A7
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FABP1 fatty acid binding protein 1, liver
FADD Fas (TNFRSF6)-associated via death domain
FAM162A family with sequence similarity 162, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBLN1 fibulin 1
FETUB fetuin B
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FN1 fibronectin 1
FNIP1 folliculin interacting protein 1
FOXL2 forkhead box L2
FURIN furin (paired basic amino acid cleaving enzyme)
GAS6 growth arrest-specific 6
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPC3 glypican 3
GPER1 G protein-coupled estrogen receptor 1
GPI glucose-6-phosphate isomerase
GPX1 glutathione peroxidase 1
GSN gelsolin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIP1 huntingtin interacting protein 1
HMGB1 high mobility group box 1
HMSD histocompatibility (minor) serpin domain containing
HRG histidine-rich glycoprotein
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HTRA2 HtrA serine peptidase 2
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFT57 intraflagellar transport 57
IGBP1 immunoglobulin (CD79A) binding protein 1
IL24 interleukin 24
IL6 interleukin 6
INTS1 integrator complex subunit 1
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6
JAK2 Janus kinase 2
KIAA0141 KIAA0141
KLF4 Kruppel-like factor 4 (gut)
KNG1 kininogen 1
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN1 lipocalin 1
LEF1 lymphoid enhancer-binding factor 1
LXN latexin
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK12 mitogen-activated protein kinase 12
MAPK9 mitogen-activated protein kinase 9
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MEN1 multiple endocrine neoplasia I
MGMT O-6-methylguanine-DNA methyltransferase
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MKL1 megakaryoblastic leukemia (translocation) 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MT3 metallothionein 3
MTCH1 mitochondrial carrier 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAIP NLR family, apoptosis inhibitory protein
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEK5 NIMA-related kinase 5
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NKX3-1 NK3 homeobox 1
NLE1 notchless homolog 1 (Drosophila)
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP12 NLR family, pyrin domain containing 12
NLRP2 NLR family, pyrin domain containing 2
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NODAL nodal growth differentiation factor
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NRD1 nardilysin (N-arginine dibasic convertase)
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAPLN papilin, proteoglycan-like sulfated glycoprotein
PARK7 parkinson protein 7
PAX2 paired box 2
PCID2 PCI domain containing 2
PCOLCE procollagen C-endopeptidase enhancer
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDCD2 programmed cell death 2
PDCD5 programmed cell death 5
PDCD6 programmed cell death 6
PEBP1 phosphatidylethanolamine binding protein 1
PERP PERP, TP53 apoptosis effector
PI15 peptidase inhibitor 15
PI16 peptidase inhibitor 16
PI3 peptidase inhibitor 3, skin-derived
PICALM phosphatidylinositol binding clathrin assembly protein
PIDD1 p53-induced death domain protein 1
PINK1 PTEN induced putative kinase 1
PLAUR plasminogen activator, urokinase receptor
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
POR P450 (cytochrome) oxidoreductase
PPARG peroxisome proliferator-activated receptor gamma
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRDX3 peroxiredoxin 3
PRDX5 peroxiredoxin 5
PRELID1 PRELI domain containing 1
PROL1 proline rich, lacrimal 1
PROS1 protein S (alpha)
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTTG1 pituitary tumor-transforming 1
PYCARD PYD and CARD domain containing
R3HDML R3H domain containing-like
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAG1 recombination activating gene 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RENBP renin binding protein
REST RE1-silencing transcription factor
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPS27L ribosomal protein S27-like
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SENP1 SUMO1/sentrin specific peptidase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINE3 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFN stratifin
SFRP2 secreted frizzled-related protein 2
SH3RF1 SH3 domain containing ring finger 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIRT1 sirtuin 1
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX2 SRY (sex determining region Y)-box 2
SOX7 SRY (sex determining region Y)-box 7
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative)
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPINK6 serine peptidase inhibitor, Kazal type 6
SPINK7 serine peptidase inhibitor, Kazal type 7 (putative)
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative)
SPINK9 serine peptidase inhibitor, Kazal type 9
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPINT3 serine peptidase inhibitor, Kunitz type, 3
SPINT4 serine peptidase inhibitor, Kunitz type 4
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPP2 secreted phosphoprotein 2, 24kDa
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSPO SCO-spondin
TBC1D10A TBC1 domain family, member 10A
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TNF tumor necrosis factor
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP63 tumor protein p63
TPD52L1 tumor protein D52-like 1
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
TRIAP1 TP53 regulated inhibitor of apoptosis 1
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UMODL1 uromodulin-like 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP47 ubiquitin specific peptidase 47
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VIL1 villin 1
VTN vitronectin
WFDC1 WAP four-disulfide core domain 1
WFDC10A WAP four-disulfide core domain 10A
WFDC10B WAP four-disulfide core domain 10B
WFDC12 WAP four-disulfide core domain 12
WFDC13 WAP four-disulfide core domain 13
WFDC2 WAP four-disulfide core domain 2
WFDC3 WAP four-disulfide core domain 3
WFDC5 WAP four-disulfide core domain 5
WFDC8 WAP four-disulfide core domain 8
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
WNT3A wingless-type MMTV integration site family, member 3A
WNT9A wingless-type MMTV integration site family, member 9A
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon