regulation of neuron apoptotic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. (Gene Ontology, GO_0043523)
External Link http://amigo.geneontology.org/amigo/term/GO:0043523
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Genes

186 genes participating in the regulation of neuron apoptotic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ADAM8 ADAM metallopeptidase domain 8
ADNP activity-dependent neuroprotector homeobox
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGRN agrin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKT1S1 AKT1 substrate 1 (proline-rich)
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
AMBRA1 autophagy/beclin-1 regulator 1
ANGPT1 angiopoietin 1
APOE apolipoprotein E
ASCL1 achaete-scute family bHLH transcription factor 1
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AXL AXL receptor tyrosine kinase
BARHL1 BarH-like homeobox 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BIRC8 baculoviral IAP repeat containing 8
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTG2 BTG family, member 2
C5AR1 complement component 5a receptor 1
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CDC34 cell division cycle 34
CDC42 cell division cycle 42
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHL1 cell adhesion molecule L1-like
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLCF1 cardiotrophin-like cytokine factor 1
CLN3 ceroid-lipofuscinosis, neuronal 3
CNTF ciliary neurotrophic factor
CNTFR ciliary neurotrophic factor receptor
CORO1A coronin, actin binding protein, 1A
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRLF1 cytokine receptor-like factor 1
DDIT3 DNA-damage-inducible transcript 3
DLX1 distal-less homeobox 1
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DRAXIN dorsal inhibitory axon guidance protein
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR1 early growth response 1
EPHA7 EPH receptor A7
ERBB3 erb-b2 receptor tyrosine kinase 3
F2R coagulation factor II (thrombin) receptor
FAIM2 Fas apoptotic inhibitory molecule 2
FASLG Fas ligand (TNF superfamily, member 6)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR3 fibroblast growth factor receptor 3
FOXB1 forkhead box B1
FOXO3 forkhead box O3
FYN FYN proto-oncogene, Src family tyrosine kinase
G6PD glucose-6-phosphate dehydrogenase
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GATA3 GATA binding protein 3
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GDF5 growth differentiation factor 5
GDNF glial cell derived neurotrophic factor
GFRAL GDNF family receptor alpha like
GPI glucose-6-phosphate isomerase
GPX1 glutathione peroxidase 1
GRID2 glutamate receptor, ionotropic, delta 2
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM4 glutamate receptor, metabotropic 4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HTT huntingtin
ILK integrin-linked kinase
ISL1 ISL LIM homeobox 1
ITGA1 integrin, alpha 1
ITSN1 intersectin 1 (SH3 domain protein)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNIP3 Kv channel interacting protein 3, calsenilin
KDM2B lysine (K)-specific demethylase 2B
KIF14 kinesin family member 14
KRAS Kirsten rat sarcoma viral oncogene homolog
LGMN legumain
LIG4 ligase IV, DNA, ATP-dependent
LRP1 low density lipoprotein receptor-related protein 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MCL1 myeloid cell leukemia 1
MDK midkine (neurite growth-promoting factor 2)
MECP2 methyl CpG binding protein 2
MEF2C myocyte enhancer factor 2C
MSH2 mutS homolog 2
MT3 metallothionein 3
MUSK muscle, skeletal, receptor tyrosine kinase
NAE1 NEDD8 activating enzyme E1 subunit 1
NAIP NLR family, apoptosis inhibitory protein
NCF2 neutrophil cytosolic factor 2
NDNF neuron-derived neurotrophic factor
NEFL neurofilament, light polypeptide
NES nestin
NF1 neurofibromin 1
NGF nerve growth factor (beta polypeptide)
NLRC4 NLR family, CARD domain containing 4
NONO non-POU domain containing, octamer-binding
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRBP2 nuclear receptor binding protein 2
NRP1 neuropilin 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTF3 neurotrophin 3
NTF4 neurotrophin 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OXR1 oxidation resistance 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PCSK9 proprotein convertase subtilisin/kexin type 9
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PINK1 PTEN induced putative kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POU4F1 POU class 4 homeobox 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPT1 palmitoyl-protein thioesterase 1
PRDX2 peroxiredoxin 2
PRKCG protein kinase C, gamma
PRKCI protein kinase C, iota
PSEN1 presenilin 1
PTK2B protein tyrosine kinase 2 beta
RAPSN receptor-associated protein of the synapse
RASA1 RAS p21 protein activator (GTPase activating protein) 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SCT secretin
SET SET nuclear proto-oncogene
SIGMAR1 sigma non-opioid intracellular receptor 1
SIX1 SIX homeobox 1
SIX4 SIX homeobox 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCB synuclein, beta
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SRPK2 SRSF protein kinase 2
STAMBP STAM binding protein
STAR steroidogenic acute regulatory protein
STXBP1 syntaxin binding protein 1
SYNGAP1 synaptic Ras GTPase activating protein 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TOX3 TOX high mobility group box family member 3
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TRIM2 tripartite motif containing 2
TYRO3 TYRO3 protein tyrosine kinase
UBE2M ubiquitin-conjugating enzyme E2M
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UNC5B unc-5 homolog B (C. elegans)
WFS1 Wolfram syndrome 1 (wolframin)
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZPR1 ZPR1 zinc finger