regulation of intrinsic apoptotic signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway. (Gene Ontology, GO_2001242)
External Link http://amigo.geneontology.org/amigo/term/GO:2001242
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Genes

142 genes participating in the regulation of intrinsic apoptotic signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BAD BCL2-associated agonist of cell death
BAG5 BCL2-associated athanogene 5
BAX BCL2-associated X protein
BCAP31 B-cell receptor-associated protein 31
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L12 BCL2-like 12 (proline rich)
BCL2L2 BCL2-like 2
BCLAF1 BCL2-associated transcription factor 1
BDKRB2 bradykinin receptor B2
BID BH3 interacting domain death agonist
BMF Bcl2 modifying factor
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CAV1 caveolin 1, caveolae protein, 22kDa
CCAR2 cell cycle and apoptosis regulator 2
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CLU clusterin
CREB3 cAMP responsive element binding protein 3
CREB3L1 cAMP responsive element binding protein 3-like 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYLD cylindromatosis (turban tumor syndrome)
DAPK2 death-associated protein kinase 2
DDIT3 DNA-damage-inducible transcript 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DFNA5 deafness, autosomal dominant 5
DNM1L dynamin 1-like
EI24 etoposide induced 2.4
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELL3 elongation factor RNA polymerase II-like 3
EPO erythropoietin
FBXO18 F-box protein, helicase, 18
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FIGNL1 fidgetin-like 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
G2E3 G2/M-phase specific E3 ubiquitin protein ligase
GCG glucagon
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPX1 glutathione peroxidase 1
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
HDAC2 histone deacetylase 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSPB1 heat shock 27kDa protein 1
HTRA2 HtrA serine peptidase 2
HYOU1 hypoxia up-regulated 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL19 interleukin 19
IL20RA interleukin 20 receptor, alpha
ING2 inhibitor of growth family, member 2
INS insulin
IVNS1ABP influenza virus NS1A binding protein
KDM1A lysine (K)-specific demethylase 1A
LCK LCK proto-oncogene, Src family tyrosine kinase
LRRK2 leucine-rich repeat kinase 2
MAPK7 mitogen-activated protein kinase 7
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MCL1 myeloid cell leukemia 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP9 matrix metallopeptidase 9
MSX1 msh homeobox 1
MUC1 mucin 1, cell surface associated
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NCK1 NCK adaptor protein 1
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NFE2L2 nuclear factor, erythroid 2-like 2
NKX3-1 NK3 homeobox 1
NME5 NME/NM23 family member 5
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NONO non-POU domain containing, octamer-binding
NOX1 NADPH oxidase 1
OPA1 optic atrophy 1 (autosomal dominant)
P4HB prolyl 4-hydroxylase, beta polypeptide
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARL presenilin associated, rhomboid-like
PDIA2 protein disulfide isomerase family A, member 2
PDILT protein disulfide isomerase-like, testis expressed
PDX1 pancreatic and duodenal homeobox 1
PGAP2 post-GPI attachment to proteins 2
PIAS4 protein inhibitor of activated STAT, 4
PINK1 PTEN induced putative kinase 1
PLAGL2 pleiomorphic adenoma gene-like 2
PLAUR plasminogen activator, urokinase receptor
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPIF peptidylprolyl isomerase F
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PYCARD PYD and CARD domain containing
RAD9A RAD9 homolog A (S. pombe)
RIPK3 receptor-interacting serine-threonine kinase 3
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEPT4 septin 4
SERINC3 serine incorporator 3
SFPQ splicing factor proline/glutamine-rich
SFRP2 secreted frizzled-related protein 2
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT1 sirtuin 1
SKIL SKI-like proto-oncogene
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPOP speckle-type POZ protein
SRC SRC proto-oncogene, non-receptor tyrosine kinase
ST20 suppressor of tumorigenicity 20
STEAP3 STEAP family member 3, metalloreductase
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMEM161A transmembrane protein 161A
TP53 tumor protein p53
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
TRAP1 TNF receptor-associated protein 1
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIM32 tripartite motif containing 32
UBB ubiquitin B
UBQLN1 ubiquilin 1
URI1 URI1, prefoldin-like chaperone
USP47 ubiquitin specific peptidase 47
VDAC2 voltage-dependent anion channel 2
VIMP VCP-interacting membrane selenoprotein
VNN1 vanin 1
WFS1 Wolfram syndrome 1 (wolframin)
XBP1 X-box binding protein 1
YBX3 Y box binding protein 3
ZNF385A zinc finger protein 385A