regulation of innate immune response Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. (Gene Ontology, GO_0045088)
External Link http://amigo.geneontology.org/amigo/term/GO:0045088
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Genes

251 genes participating in the regulation of innate immune response biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ADAM8 ADAM metallopeptidase domain 8
ADAR adenosine deaminase, RNA-specific
AIM2 absent in melanoma 2
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ARRB2 arrestin, beta 2
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
BCL10 B-cell CLL/lymphoma 10
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BTK Bruton agammaglobulinemia tyrosine kinase
CACTIN cactin, spliceosome C complex subunit
CADM1 cell adhesion molecule 1
CARD9 caspase recruitment domain family, member 9
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CD1D CD1d molecule
CD226 CD226 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD86 CD86 molecule
CDC37 cell division cycle 37
CDK1 cyclin-dependent kinase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC7A C-type lectin domain family 7, member A
CNPY3 canopy FGF signaling regulator 3
COCH cochlin
COLEC12 collectin sub-family member 12
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREB1 cAMP responsive element binding protein 1
CRTAM cytotoxic and regulatory T cell molecule
CTSB cathepsin B
CTSK cathepsin K
CTSL cathepsin L
CTSS cathepsin S
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DMBT1 deleted in malignant brain tumors 1
DUSP10 dual specificity phosphatase 10
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
ELK1 ELK1, member of ETS oncogene family
ERAP1 endoplasmic reticulum aminopeptidase 1
EREG epiregulin
FADD Fas (TNFRSF6)-associated via death domain
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FFAR2 free fatty acid receptor 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FOS FBJ murine osteosarcoma viral oncogene homolog
HCK HCK proto-oncogene, Src family tyrosine kinase
HLA-E major histocompatibility complex, class I, E
HPX hemopexin
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFI16 interferon, gamma-inducible protein 16
IFIH1 interferon induced with helicase C domain 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IFNK interferon, kappa
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL12A interleukin 12A
IL12B interleukin 12B
IL21 interleukin 21
INS insulin
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRG1 immunoresponsive 1 homolog (mouse)
ITCH itchy E3 ubiquitin protein ligase
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
LAG3 lymphocyte-activation gene 3
LAMP1 lysosomal-associated membrane protein 1
LBP lipopolysaccharide binding protein
LGMN legumain
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LY96 lymphocyte antigen 96
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MARCO macrophage receptor with collagenous structure
MAVS mitochondrial antiviral signaling protein
MB21D1 Mab-21 domain containing 1
MED1 mediator complex subunit 1
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MICA MHC class I polypeptide-related sequence A
MMP2 matrix metallopeptidase 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYD88 myeloid differentiation primary response 88
MYO1F myosin IF
NCR1 natural cytotoxicity triggering receptor 1
NCR3 natural cytotoxicity triggering receptor 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLRC4 NLR family, CARD domain containing 4
NLRC5 NLR family, CARD domain containing 5
NLRX1 NLR family member X1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
OTULIN OTU deubiquitinase with linear linkage specificity
PARP9 poly (ADP-ribose) polymerase family, member 9
PELI1 pellino E3 ubiquitin protein ligase 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PIAS1 protein inhibitor of activated STAT, 1
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PLSCR1 phospholipid scramblase 1
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPARG peroxisome proliferator-activated receptor gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKCE protein kinase C, epsilon
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PVR poliovirus receptor
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PYCARD PYD and CARD domain containing
REG3G regenerating islet-derived 3 gamma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFTN1 raftlin, lipid raft linker 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RNF135 ring finger protein 135
RPS19 ribosomal protein S19
RPS27A ribosomal protein S27a
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A14 S100 calcium binding protein A14
SAMHD1 SAM domain and HD domain 1
SARM1 sterile alpha and TIR motif containing 1
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SIN3A SIN3 transcription regulator family member A
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SUMO1 small ubiquitin-like modifier 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TKFC triokinase/FMN cyclase
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMEM173 transmembrane protein 173
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TNIP3 TNFAIP3 interacting protein 3
TRAF3 TNF receptor-associated factor 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAFD1 TRAF-type zinc finger domain containing 1
TRIL TLR4 interactor with leucine-rich repeats
TRIM5 tripartite motif containing 5
TXK TXK tyrosine kinase
TYK2 tyrosine kinase 2
TYRO3 TYRO3 protein tyrosine kinase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2N ubiquitin-conjugating enzyme E2N
UNC93B1 unc-93 homolog B1 (C. elegans)
USP18 ubiquitin specific peptidase 18
WNT5A wingless-type MMTV integration site family, member 5A
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBP1 Z-DNA binding protein 1