regulation of extrinsic apoptotic signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway. (Gene Ontology, GO_2001236)
External Link http://amigo.geneontology.org/amigo/term/GO:2001236
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Genes

154 genes participating in the regulation of extrinsic apoptotic signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACVR1 activin A receptor, type I
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR2 angiotensin II receptor, type 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AR androgen receptor
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BAX BCL2-associated X protein
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BIRC6 baculoviral IAP repeat containing 6
BMP5 bone morphogenetic protein 5
BMPR1B bone morphogenetic protein receptor, type IB
BRCA1 breast cancer 1, early onset
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CFLAR CASP8 and FADD-like apoptosis regulator
COL2A1 collagen, type II, alpha 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTTN cortactin
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYLD cylindromatosis (turban tumor syndrome)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAPK1 death-associated protein kinase 1
DAPK3 death-associated protein kinase 3
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DEDD2 death effector domain containing 2
DEPTOR DEP domain containing MTOR-interacting protein
EYA1 EYA transcriptional coactivator and phosphatase 1
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FEM1B fem-1 homolog b (C. elegans)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF10 fibroblast growth factor 10
FGFR1 fibroblast growth factor receptor 1
FGG fibrinogen gamma chain
FYN FYN proto-oncogene, Src family tyrosine kinase
G0S2 G0/G1 switch 2
GAS1 growth arrest-specific 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GDNF glial cell derived neurotrophic factor
GFRAL GDNF family receptor alpha like
GPER1 G protein-coupled estrogen receptor 1
GPX1 glutathione peroxidase 1
GSTP1 glutathione S-transferase pi 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HMGB2 high mobility group box 2
HMOX1 heme oxygenase 1
HTRA2 HtrA serine peptidase 2
HTT huntingtin
HYAL2 hyaluronoglucosaminidase 2
ICAM1 intercellular adhesion molecule 1
IFI6 interferon, alpha-inducible protein 6
IGF1 insulin-like growth factor 1 (somatomedin C)
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IL7 interleukin 7
INHBA inhibin, beta A
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
ITM2C integral membrane protein 2C
JAK3 Janus kinase 3
KIAA1324 KIAA1324
LGALS3 lectin, galactoside-binding, soluble, 3
LMNA lamin A/C
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MADD MAP-kinase activating death domain
MAL mal, T-cell differentiation protein
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK7 mitogen-activated protein kinase 7
MCL1 myeloid cell leukemia 1
NF1 neurofibromin 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS3 nitric oxide synthase 3 (endothelial cell)
NRP1 neuropilin 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PARK7 parkinson protein 7
PDIA3 protein disulfide isomerase family A, member 3
PEA15 phosphoprotein enriched in astrocytes 15
PELI3 pellino E3 ubiquitin protein ligase family member 3
PF4 platelet factor 4
PHIP pleckstrin homology domain interacting protein
PIDD1 p53-induced death domain protein 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PSEN2 presenilin 2
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PYCARD PYD and CARD domain containing
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1CC1 RB1-inducible coiled-coil 1
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX3 runt-related transcription factor 3
SCG2 secretogranin II
SCRT2 scratch family zinc finger 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SGMS1 sphingomyelin synthase 1
SH3RF1 SH3 domain containing ring finger 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SKIL SKI-like proto-oncogene
SNAI2 snail family zinc finger 2
SP100 SP100 nuclear antigen
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPX sushi-repeat containing protein, X-linked
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
STRADB STE20-related kinase adaptor beta
STX4 syntaxin 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMC8 transmembrane channel-like 8
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRADD TNFRSF1A-associated via death domain
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRPS1 trichorhinophalangeal syndrome I
UNC5B unc-5 homolog B (C. elegans)
WWOX WW domain containing oxidoreductase
YAP1 Yes-associated protein 1
ZC3HC1 zinc finger, C3HC-type containing 1
ZMYND11 zinc finger, MYND-type containing 11
ZSWIM2 zinc finger, SWIM-type containing 2