regulation of cell activation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. (Gene Ontology, GO_0050865)
External Link http://amigo.geneontology.org/amigo/term/GO:0050865
Similar Terms
Downloads & Tools

Genes

415 genes participating in the regulation of cell activation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABR active BCR-related
ADA adenosine deaminase
ADAM8 ADAM metallopeptidase domain 8
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADK adenosine kinase
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
AHR aryl hydrocarbon receptor
AIF1 allograft inflammatory factor 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX12 arachidonate 12-lipoxygenase
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APLF aprataxin and PNKP like factor
APOE apolipoprotein E
ATM ATM serine/threonine kinase
ATP11C ATPase, class VI, type 11C
AXL AXL receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BLM Bloom syndrome, RecQ helicase-like
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
BMP4 bone morphogenetic protein 4
BPI bactericidal/permeability-increasing protein
BST1 bone marrow stromal cell antigen 1
BTK Bruton agammaglobulinemia tyrosine kinase
BTLA B and T lymphocyte associated
BTN2A2 butyrophilin, subfamily 2, member A2
C10ORF54 chromosome 10 open reading frame 54
C12ORF4 chromosome 12 open reading frame 4
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN3 calpain 3, (p94)
CARD11 caspase recruitment domain family, member 11
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL21 chemokine (C-C motif) ligand 21
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR7 chemokine (C-C motif) receptor 7
CD1D CD1d molecule
CD2 CD2 molecule
CD209 CD209 molecule
CD226 CD226 molecule
CD24 CD24 molecule
CD247 CD247 molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD300A CD300a molecule
CD37 CD37 molecule
CD38 CD38 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD5 CD5 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD80 CD80 molecule
CD81 CD81 molecule
CD83 CD83 molecule
CD86 CD86 molecule
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLC Charcot-Leyden crystal galectin
CLCF1 cardiotrophin-like cytokine factor 1
CLPTM1 cleft lip and palate associated transmembrane protein 1
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CORO1A coronin, actin binding protein, 1A
CRHR1 corticotropin releasing hormone receptor 1
CSK c-src tyrosine kinase
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYLD cylindromatosis (turban tumor syndrome)
DHPS deoxyhypusine synthase
DLG1 discs, large homolog 1 (Drosophila)
DMTN dematin actin binding protein
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DPP4 dipeptidyl-peptidase 4
DTX1 deltex 1, E3 ubiquitin ligase
DUSP3 dual specificity phosphatase 3
EBI3 Epstein-Barr virus induced 3
EFNB1 ephrin-B1
EGR3 early growth response 3
ERBB2 erb-b2 receptor tyrosine kinase 2
EXOSC3 exosome component 3
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FBXO7 F-box protein 7
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FER fer (fps/fes related) tyrosine kinase
FES FES proto-oncogene, tyrosine kinase
FGF10 fibroblast growth factor 10
FGR FGR proto-oncogene, Src family tyrosine kinase
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FOXF1 forkhead box F1
FOXJ1 forkhead box J1
FOXN1 forkhead box N1
FOXP3 forkhead box P3
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GAL galanin/GMAP prepropeptide
GAS6 growth arrest-specific 6
GATA3 GATA binding protein 3
GJD4 gap junction protein, delta 4, 40.1kDa
GLI2 GLI family zinc finger 2
GLI3 GLI family zinc finger 3
GLMN glomulin, FKBP associated protein
GP5 glycoprotein V (platelet)
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GPER1 G protein-coupled estrogen receptor 1
GPR183 G protein-coupled receptor 183
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HES1 hes family bHLH transcription factor 1
HHLA2 HERV-H LTR-associating 2
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HLX H2.0-like homeobox
HMGB3 high mobility group box 3
HMOX1 heme oxygenase 1
HPS1 Hermansky-Pudlak syndrome 1
HRG histidine-rich glycoprotein
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
ICOS inducible T-cell co-stimulator
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IFNA2 interferon, alpha 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IHH indian hedgehog
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL15 interleukin 15
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL1RL2 interleukin 1 receptor-like 2
IL2 interleukin 2
IL20RB interleukin 20 receptor beta
IL21 interleukin 21
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL27 interleukin 27
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL31RA interleukin 31 receptor A
IL33 interleukin 33
IL36B interleukin 36, beta
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
IL7R interleukin 7 receptor
INHA inhibin, alpha
INHBA inhibin, beta A
IRF1 interferon regulatory factor 1
IRF4 interferon regulatory factor 4
IRS2 insulin receptor substrate 2
ITCH itchy E3 ubiquitin protein ligase
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITPKB inositol-trisphosphate 3-kinase B
JAK2 Janus kinase 2
JAK3 Janus kinase 3
LAG3 lymphocyte-activation gene 3
LAMP1 lysosomal-associated membrane protein 1
LAT linker for activation of T cells
LAX1 lymphocyte transmembrane adaptor 1
LBP lipopolysaccharide binding protein
LCK LCK proto-oncogene, Src family tyrosine kinase
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMO4 LIM domain only 4
LRRC32 leucine rich repeat containing 32
LST1 leukocyte specific transcript 1
LYN LYN proto-oncogene, Src family tyrosine kinase
LYST lysosomal trafficking regulator
MALT1 MALT1 paracaspase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MEF2C myocyte enhancer factor 2C
MERTK MER proto-oncogene, tyrosine kinase
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MILR1 mast cell immunoglobulin-like receptor 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MNDA myeloid cell nuclear differentiation antigen
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MZB1 marginal zone B and B1 cell-specific protein
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKAP1L NCK-associated protein 1-like
NDFIP1 Nedd4 family interacting protein 1
NFAM1 NFAT activating protein with ITAM motif 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NKAP NFKB activating protein
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRARP NOTCH-regulated ankyrin repeat protein
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAWR PRKC, apoptosis, WT1, regulator
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCID2 PCI domain containing 2
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PDPN podoplanin
PELI1 pellino E3 ubiquitin protein ligase 1
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G10 phospholipase A2, group X
PLEK pleckstrin
PLSCR1 phospholipid scramblase 1
PNP purine nucleoside phosphorylase
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRDM1 PR domain containing 1, with ZNF domain
PRELID1 PRELI domain containing 1
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKG1 protein kinase, cGMP-dependent, type I
PRNP prion protein
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRE protein tyrosine phosphatase, receptor type, E
PTPRJ protein tyrosine phosphatase, receptor type, J
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PYCARD PYD and CARD domain containing
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAG1 recombination activating gene 1
RARA retinoic acid receptor, alpha
RC3H1 ring finger and CCCH-type domains 1
RHBDD3 rhomboid domain containing 3
RICTOR RPTOR independent companion of MTOR, complex 2
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SART1 squamous cell carcinoma antigen recognized by T cells
SASH3 SAM and SH3 domain containing 3
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SFTPD surfactant protein D
SHH sonic hedgehog
SHPK sedoheptulokinase
SIRPG signal-regulatory protein gamma
SIT1 signaling threshold regulating transmembrane adaptor 1
SLA2 Src-like-adaptor 2
SLC46A2 solute carrier family 46, member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX4 sorting nexin 4
SNX6 sorting nexin 6
SOCS5 suppressor of cytokine signaling 5
SOCS6 suppressor of cytokine signaling 6
SOD1 superoxide dismutase 1, soluble
SOX11 SRY (sex determining region Y)-box 11
SOX13 SRY (sex determining region Y)-box 13
SOX15 SRY (sex determining region Y)-box 15
SPACA3 sperm acrosome associated 3
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTA1 spectrin, alpha, erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STX4 syntaxin 4
STXBP2 syntaxin binding protein 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SYK spleen tyrosine kinase
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TBC1D10C TBC1 domain family, member 10C
TBX21 T-box 21
TEC tec protein tyrosine kinase
TESPA1 thymocyte expressed, positive selection associated 1
TFF2 trefoil factor 2
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
THBS1 thrombospondin 1
THOC1 THO complex 1
THY1 Thy-1 cell surface antigen
TICAM1 toll-like receptor adaptor molecule 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR4 toll-like receptor 4
TMIGD2 transmembrane and immunoglobulin domain containing 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNIP2 TNFAIP3 interacting protein 2
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSPAN32 tetraspanin 32
TYRO3 TYRO3 protein tyrosine kinase
UBASH3B ubiquitin associated and SH3 domain containing B
UNC13D unc-13 homolog D (C. elegans)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAMP3 vesicle-associated membrane protein 3
VAMP7 vesicle-associated membrane protein 7
VAMP8 vesicle-associated membrane protein 8
VAV1 vav 1 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VNN1 vanin 1
VSIG4 V-set and immunoglobulin domain containing 4
VTCN1 V-set domain containing T cell activation inhibitor 1
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
XBP1 X-box binding protein 1
XCL1 chemokine (C motif) ligand 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1
ZBTB16 zinc finger and BTB domain containing 16
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H8 zinc finger CCCH-type containing 8
ZEB1 zinc finger E-box binding homeobox 1
ZNF335 zinc finger protein 335
ZNHIT1 zinc finger, HIT-type containing 1
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4