reductase Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

184 genes co-occuring with the biological term reductase in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1B15 aldo-keto reductase family 1, member B15
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
AKR1D1 aldo-keto reductase family 1, member D1
AKR1E2 aldo-keto reductase family 1, member E2
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANXA2 annexin A2
APOA1 apolipoprotein A-I
AS3MT arsenite methyltransferase
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
AUP1 ancient ubiquitous protein 1
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BLVRA biliverdin reductase A
BRD2 bromodomain containing 2
CAT catalase
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CBR4 carbonyl reductase 4
CBS cystathionine-beta-synthase
CCND1 cyclin D1
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDKN2A cyclin-dependent kinase inhibitor 2A
CHGA chromogranin A
CKM creatine kinase, muscle
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
CPB2 carboxypeptidase B2 (plasma)
CRYM crystallin, mu
CRYZ crystallin, zeta (quinone reductase)
CTSD cathepsin D
CYB5A cytochrome b5 type A (microsomal)
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
CYB5R3 cytochrome b5 reductase 3
CYB5R4 cytochrome b5 reductase 4
CYBRD1 cytochrome b reductase 1
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DCK deoxycytidine kinase
DCXR dicarbonyl/L-xylulose reductase
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DHFR dihydrofolate reductase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHRS3 dehydrogenase/reductase (SDR family) member 3
DHRS4 dehydrogenase/reductase (SDR family) member 4
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DPYD dihydropyrimidine dehydrogenase
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
FAR1 fatty acyl CoA reductase 1
FAR2 fatty acyl CoA reductase 2
FDXR ferredoxin reductase
FHIT fragile histidine triad
FMO3 flavin containing monooxygenase 3
FOXO1 forkhead box O1
FOXO3 forkhead box O3
GLRX glutaredoxin (thioltransferase)
GMPR2 guanosine monophosphate reductase 2
GPX1 glutathione peroxidase 1
GPX4 glutathione peroxidase 4
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
GSTO1 glutathione S-transferase omega 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HBB hemoglobin, beta
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICAM1 intercellular adhesion molecule 1
IFI30 interferon, gamma-inducible protein 30
IL6 interleukin 6
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KDSR 3-ketodihydrosphingosine reductase
LBR lamin B receptor
LDLR low density lipoprotein receptor
MAP2K2 mitogen-activated protein kinase kinase 2
MARC1 mitochondrial amidoxime reducing component 1
MARC2 mitochondrial amidoxime reducing component 2
MBTPS1 membrane-bound transcription factor peptidase, site 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR21 microRNA 21
MIR214 microRNA 214
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type
MSRA methionine sulfoxide reductase A
MSRB2 methionine sulfoxide reductase B2
MSRB3 methionine sulfoxide reductase B3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGB neuroglobin
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRG1 neuregulin 1
PARK3 Parkinson disease 3 (autosomal dominant, Lewy body)
PECR peroxisomal trans-2-enoyl-CoA reductase
PGK1 phosphoglycerate kinase 1
PLAU plasminogen activator, urokinase
POR P450 (cytochrome) oxidoreductase
PRDX1 peroxiredoxin 1
PRDX3 peroxiredoxin 3
PRDX5 peroxiredoxin 5
PTGES prostaglandin E synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTK2 protein tyrosine kinase 2
RARA retinoic acid receptor, alpha
RDH10 retinol dehydrogenase 10 (all-trans)
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RUNX2 runt-related transcription factor 2
SAMHD1 SAM domain and HD domain 1
SCARA3 scavenger receptor class A, member 3
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SELK selenoprotein K
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN2 sestrin 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SRD5A3 steroid 5 alpha-reductase 3
SREBF2 sterol regulatory element binding transcription factor 2
STEAP2 STEAP family member 2, metalloreductase
TECR trans-2,3-enoyl-CoA reductase
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TM7SF2 transmembrane 7 superfamily member 2
TMX4 thioredoxin-related transmembrane protein 4
TNF tumor necrosis factor
TP53 tumor protein p53
TPMT thiopurine S-methyltransferase
TXN thioredoxin
TXN2 thioredoxin 2
TXNRD1 thioredoxin reductase 1
TXNRD2 thioredoxin reductase 2
TXNRD3 thioredoxin reductase 3
TYMS thymidylate synthetase
UQCRB ubiquinol-cytochrome c reductase binding protein
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VIMP VCP-interacting membrane selenoprotein
VKORC1 vitamin K epoxide reductase complex, subunit 1