reciprocal meiotic recombination Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity. (Gene Ontology, GO_0007131)
External Link http://amigo.geneontology.org/amigo/term/GO:0007131
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Genes

26 genes participating in the reciprocal meiotic recombination biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ATM ATM serine/threonine kinase
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
DMC1 DNA meiotic recombinase 1
KLHDC3 kelch domain containing 3
MLH3 mutL homolog 3
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSH3 mutS homolog 3
MSH4 mutS homolog 4
MSH5 mutS homolog 5
MSH6 mutS homolog 6
RAD21 RAD21 homolog (S. pombe)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RAD51C RAD51 paralog C
RAD51D RAD51 paralog D
RAD54B RAD54 homolog B (S. cerevisiae)
REC8 REC8 meiotic recombination protein
RNF212 ring finger protein 212
SPO11 SPO11 meiotic protein covalently bound to DSB
STRA8 stimulated by retinoic acid 8
SYCE3 synaptonemal complex central element protein 3
SYCP1 synaptonemal complex protein 1
TEX11 testis expressed 11
TRIP13 thyroid hormone receptor interactor 13