receptor-mediated endocytosis Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. (Gene Ontology, GO_0006898)
External Link http://amigo.geneontology.org/amigo/term/GO:0006898
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Genes

183 genes participating in the receptor-mediated endocytosis biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACKR2 atypical chemokine receptor 2
ACKR3 atypical chemokine receptor 3
ACKR4 atypical chemokine receptor 4
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
AMN amnion associated transmembrane protein
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOBR apolipoprotein B receptor
APOE apolipoprotein E
APOL1 apolipoprotein L, 1
ARHGAP27 Rho GTPase activating protein 27
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASGR1 asialoglycoprotein receptor 1
ASGR2 asialoglycoprotein receptor 2
CALCR calcitonin receptor
CALCRL calcitonin receptor-like
CALR calreticulin
CANX calnexin
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CAV3 caveolin 3
CD163 CD163 molecule
CD163L1 CD163 molecule-like 1
CD36 CD36 molecule (thrombospondin receptor)
CD5 CD5 molecule
CD5L CD5 molecule-like
CD6 CD6 molecule
CETP cholesteryl ester transfer protein, plasma
CFI complement factor I
CLEC9A C-type lectin domain family 9, member A
CLN3 ceroid-lipofuscinosis, neuronal 3
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
CLTCL1 clathrin, heavy chain-like 1
CNTN2 contactin 2 (axonal)
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COLEC11 collectin sub-family member 11
COLEC12 collectin sub-family member 12
CTTN cortactin
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBNL drebrin-like
DMBT1 deleted in malignant brain tumors 1
DNM1 dynamin 1
DNM2 dynamin 2
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
ENDOU endonuclease, polyU-specific
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
EPS15 epidermal growth factor receptor pathway substrate 15
EZR ezrin
FCHO1 FCH domain only 1
FCHO2 FCH domain only 2
FNBP1L formin binding protein 1-like
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
GAK cyclin G associated kinase
GRB2 growth factor receptor-bound protein 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRK4 G protein-coupled receptor kinase 4
HBB hemoglobin, beta
HHIPL1 HHIP-like 1
HIP1R huntingtin interacting protein 1 related
HP haptoglobin
HPR haptoglobin-related protein
HPX hemopexin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HYOU1 hypoxia up-regulated 1
IGF2R insulin-like growth factor 2 receptor
ILDR1 immunoglobulin-like domain containing receptor 1
LDLR low density lipoprotein receptor
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMBRD1 LMBR1 domain containing 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LOXL4 lysyl oxidase-like 4
LRP1 low density lipoprotein receptor-related protein 1
LRP12 low density lipoprotein receptor-related protein 12
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
LRP3 low density lipoprotein receptor-related protein 3
LRP6 low density lipoprotein receptor-related protein 6
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
M6PR mannose-6-phosphate receptor (cation dependent)
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MARCO macrophage receptor with collagenous structure
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MICALL1 MICAL-like 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRC1 mannose receptor, C type 1
MSR1 macrophage scavenger receptor 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NLGN3 neuroligin 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PGBD1 piggyBac transposable element derived 1
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PICALM phosphatidylinositol binding clathrin assembly protein
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLD2 phospholipase D2
PPT1 palmitoyl-protein thioesterase 1
PRG4 proteoglycan 4
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB31 RAB31, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAMP3 receptor (G protein-coupled) activity modifying protein 3
REPS1 RALBP1 associated Eps domain containing 1
SAA1 serum amyloid A1
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SCARA3 scavenger receptor class A, member 3
SCARA5 scavenger receptor class A, member 5
SCARB1 scavenger receptor class B, member 1
SCARF1 scavenger receptor class F, member 1
SCARF2 scavenger receptor class F, member 2
SCGB3A2 secretoglobin, family 3A, member 2
SCYL2 SCY1-like 2 (S. cerevisiae)
SFTPD surfactant protein D
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX1 sorting nexin 1
SNX17 sorting nexin 17
SNX9 sorting nexin 9
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SSC4D scavenger receptor cysteine rich family, 4 domains
SSC5D scavenger receptor cysteine rich family, 5 domains
STAB1 stabilin 1
STAB2 stabilin 2
SUSD2 sushi domain containing 2
TFR2 transferrin receptor 2
TFRC transferrin receptor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TINAG tubulointerstitial nephritis antigen
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMPRSS13 transmembrane protease, serine 13
TMPRSS15 transmembrane protease, serine 15
TMPRSS2 transmembrane protease, serine 2
TMPRSS3 transmembrane protease, serine 3
TMPRSS4 transmembrane protease, serine 4
TMPRSS5 transmembrane protease, serine 5
ULK1 unc-51 like autophagy activating kinase 1
VLDLR very low density lipoprotein receptor
VTN vitronectin