reactive oxygen species metabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. (Gene Ontology, GO_0072593)
External Link http://amigo.geneontology.org/amigo/term/GO:0072593
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Genes

108 genes participating in the reactive oxygen species metabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX12 arachidonate 12-lipoxygenase
AOX1 aldehyde oxidase 1
ARG2 arginase 2
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATPIF1 ATPase inhibitory factor 1
BCL2 B-cell CLL/lymphoma 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCS copper chaperone for superoxide dismutase
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTGF connective tissue growth factor
CYB5R4 cytochrome b5 reductase 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDIT4 DNA-damage-inducible transcript 4
DHFR dihydrofolate reductase
DNM2 dynamin 2
DRD5 dopamine receptor D5
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DUOXA1 dual oxidase maturation factor 1
DUOXA2 dual oxidase maturation factor 2
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EPHX2 epoxide hydrolase 2, cytoplasmic
EPX eosinophil peroxidase
FANCC Fanconi anemia, complementation group C
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCH1 GTP cyclohydrolase 1
GCHFR GTP cyclohydrolase I feedback regulator
GLS2 glutaminase 2 (liver, mitochondrial)
GPX1 glutathione peroxidase 1
GPX3 glutathione peroxidase 3
GPX4 glutathione peroxidase 4
HBB hemoglobin, beta
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IL19 interleukin 19
LPO lactoperoxidase
LRRK2 leucine-rich repeat kinase 2
LYPLA1 lysophospholipase I
MAOB monoamine oxidase B
MPO myeloperoxidase
MPV17 MpV17 mitochondrial inner membrane protein
MT-ND2 MTND2
MT3 metallothionein 3
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NNT nicotinamide nucleotide transhydrogenase
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOSIP nitric oxide synthase interacting protein
NOSTRIN nitric oxide synthase trafficking
NOX1 NADPH oxidase 1
NOX3 NADPH oxidase 3
NOX4 NADPH oxidase 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NOXA1 NADPH oxidase activator 1
NOXO1 NADPH oxidase organizer 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRROS negative regulator of reactive oxygen species
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARK7 parkinson protein 7
PAX2 paired box 2
PDGFB platelet-derived growth factor beta polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLA2R1 phospholipase A2 receptor 1, 180kDa
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POR P450 (cytochrome) oxidoreductase
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRDX3 peroxiredoxin 3
PRDX4 peroxiredoxin 4
PRDX6 peroxiredoxin 6
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRG3 proteoglycan 3
PRKG2 protein kinase, cGMP-dependent, type II
PTS 6-pyruvoyltetrahydropterin synthase
PXDN peroxidasin
PXDNL peroxidasin-like
RFK riboflavin kinase
RORA RAR-related orphan receptor A
SFTPD surfactant protein D
SH3PXD2A SH3 and PX domains 2A
SH3PXD2B SH3 and PX domains 2B
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TLR2 toll-like receptor 2
TPO thyroid peroxidase
VAV1 vav 1 guanine nucleotide exchange factor
WASL Wiskott-Aldrich syndrome-like
ZDHHC21 zinc finger, DHHC-type containing 21