reactions Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

260 genes co-occuring with the biological term reactions in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACE angiotensin I converting enzyme
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALB albumin
ALDH1L2 aldehyde dehydrogenase 1 family, member L2
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALOX12 arachidonate 12-lipoxygenase
ALOX15 arachidonate 15-lipoxygenase
ANGPT2 angiopoietin 2
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
ASPG asparaginase
ATR ATR serine/threonine kinase
AZU1 azurocidin 1
B2M beta-2-microglobulin
BACE1 beta-site APP-cleaving enzyme 1
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CALCA calcitonin-related polypeptide alpha
CALR calreticulin
CAMP cathelicidin antimicrobial peptide
CANX calnexin
CASP14 caspase 14, apoptosis-related cysteine peptidase
CAT catalase
CBS cystathionine-beta-synthase
CCL11 chemokine (C-C motif) ligand 11
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL3 chemokine (C-C motif) ligand 3
CCR6 chemokine (C-C motif) receptor 6
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CD14 CD14 molecule
CD200 CD200 molecule
CD200R1 CD200 receptor 1
CD274 CD274 molecule
CD320 CD320 molecule
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD83 CD83 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAT choline O-acetyltransferase
CHEK1 checkpoint kinase 1
CNR2 cannabinoid receptor 2 (macrophage)
CRAT carnitine O-acetyltransferase
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTGF connective tissue growth factor
CTH cystathionine gamma-lyase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSK cathepsin K
CXCR5 chemokine (C-X-C motif) receptor 5
CYBB cytochrome b-245, beta polypeptide
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYSLTR2 cysteinyl leukotriene receptor 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB103B defensin, beta 103B
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DLL4 delta-like 4 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DMC1 DNA meiotic recombinase 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPYD dihydropyrimidine dehydrogenase
EBI3 Epstein-Barr virus induced 3
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
F9 coagulation factor IX
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FDX1 ferredoxin 1
FEN1 flap structure-specific endonuclease 1
GCDH glutaryl-CoA dehydrogenase
GCG glucagon
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNLY granulysin
GPX1 glutathione peroxidase 1
GRB2 growth factor receptor-bound protein 2
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTT1 glutathione S-transferase theta 1
HCP5 HLA complex P5 (non-protein coding)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HP haptoglobin
HRH4 histamine receptor H4
HSPA4 heat shock 70kDa protein 4
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IDO1 indoleamine 2,3-dioxygenase 1
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL21 interleukin 21
IL22 interleukin 22
IL31 interleukin 31
IL33 interleukin 33
IL37 interleukin 37
IL6 interleukin 6
IMPAD1 inositol monophosphatase domain containing 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAK2 Janus kinase 2
KAT2B K(lysine) acetyltransferase 2B
KDR kinase insert domain receptor
LCT lactase
LDHA lactate dehydrogenase A
LEP leptin
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCPH1 microcephalin 1
MIA melanoma inhibitory activity
MIR29A microRNA 29a
MIR382 microRNA 382
MOG myelin oligodendrocyte glycoprotein
MPDZ multiple PDZ domain protein
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MT3 metallothionein 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC1 mucin 1, cell surface associated
NAMPT nicotinamide phosphoribosyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCS1 neuronal calcium sensor 1
NES nestin
NEU2 sialidase 2 (cytosolic sialidase)
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFIA nuclear factor I/A
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NPSR1 neuropeptide S receptor 1
OXTR oxytocin receptor
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDIA3 protein disulfide isomerase family A, member 3
PEBP1 phosphatidylethanolamine binding protein 1
PER1 period circadian clock 1
PER3 period circadian clock 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PLCG1 phospholipase C, gamma 1
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
POLH polymerase (DNA directed), eta
POLQ polymerase (DNA directed), theta
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PON1 paraoxonase 1
PRELID1 PRELI domain containing 1
PRF1 perforin 1 (pore forming protein)
PRM2 protamine 2
PRNP prion protein
PTGDR prostaglandin D2 receptor (DP)
PTGIS prostaglandin I2 (prostacyclin) synthase
PXDN peroxidasin
RAD52 RAD52 homolog (S. cerevisiae)
RANBP2 RAN binding protein 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RNASE3 ribonuclease, RNase A family, 3
RPSA ribosomal protein SA
RTN4 reticulon 4
SDC4 syndecan 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT5 sirtuin 5
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TALDO1 transaldolase 1
TDO2 tryptophan 2,3-dioxygenase
TET3 tet methylcytosine dioxygenase 3
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TGM2 transglutaminase 2
TK1 thymidine kinase 1, soluble
TKTL1 transketolase-like 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TP63 tumor protein p63
TPI1 triosephosphate isomerase 1
TPMT thiopurine S-methyltransferase
TPSAB1 tryptase alpha/beta 1
TPT1 tumor protein, translationally-controlled 1
TSGA10 testis specific, 10
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
URM1 ubiquitin related modifier 1
VNN1 vanin 1
XDH xanthine dehydrogenase
XPA xeroderma pigmentosum, complementation group A
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
YBX1 Y box binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZMAT3 zinc finger, matrin-type 3
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4