raubasine-6360 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the raubasine-6360 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGRA2 adhesion G protein-coupled receptor A2
ADGRL3 adhesion G protein-coupled receptor L3
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ASCL1 achaete-scute family bHLH transcription factor 1
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
C7ORF43 chromosome 7 open reading frame 43
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CC2D1A coiled-coil and C2 domain containing 1A
CIB2 calcium and integrin binding family member 2
CTNND2 catenin (cadherin-associated protein), delta 2
CTNS cystinosin, lysosomal cystine transporter
CUL7 cullin 7
CYFIP2 cytoplasmic FMR1 interacting protein 2
DBF4B DBF4 zinc finger B
DCAF11 DDB1 and CUL4 associated factor 11
DNAAF1 dynein, axonemal, assembly factor 1
DTNA dystrobrevin, alpha
DVL2 dishevelled segment polarity protein 2
DZIP1 DAZ interacting zinc finger protein 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFNB3 ephrin-B3
EML2 echinoderm microtubule associated protein like 2
FAM65B family with sequence similarity 65, member B
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
GJA8 gap junction protein, alpha 8, 50kDa
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GRAMD1C GRAM domain containing 1C
HIST1H1D histone cluster 1, H1d
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXB5 homeobox B5
IBSP integrin-binding sialoprotein
IFT122 intraflagellar transport 122
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IL2 interleukin 2
IL5RA interleukin 5 receptor, alpha
JPH3 junctophilin 3
LDB1 LIM domain binding 1
LOC81691 exonuclease NEF-sp
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK8 mitogen-activated protein kinase 8
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MUC3A mucin 3A, cell surface associated
MXRA8 matrix-remodelling associated 8
N4BP1 NEDD4 binding protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NOX1 NADPH oxidase 1
NPTXR neuronal pentraxin receptor
NRXN3 neurexin 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN2 oxidative stress induced growth inhibitor family member 2
PDLIM3 PDZ and LIM domain 3
PPARD peroxisome proliferator-activated receptor delta
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRELP proline/arginine-rich end leucine-rich repeat protein
RAD50 RAD50 homolog (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
REST RE1-silencing transcription factor
RIMS3 regulating synaptic membrane exocytosis 3
RNF122 ring finger protein 122
RPL13P5 ribosomal protein L13 pseudogene 5
RPL35A ribosomal protein L35a
SEPP1 selenoprotein P, plasma, 1
SERGEF secretion regulating guanine nucleotide exchange factor
SETD8 SET domain containing (lysine methyltransferase) 8
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC22A18 solute carrier family 22, member 18
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
STK16 serine/threonine kinase 16
SUN1 Sad1 and UNC84 domain containing 1
SUSD5 sushi domain containing 5
TBC1D30 TBC1 domain family, member 30
TBCD tubulin folding cofactor D
TBXA2R thromboxane A2 receptor
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TM4SF1 transmembrane 4 L six family member 1
TMF1 TATA element modulatory factor 1
TREX1 three prime repair exonuclease 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSPAN2 tetraspanin 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VWA1 von Willebrand factor A domain containing 1
WDR25 WD repeat domain 25
YIPF4 Yip1 domain family, member 4
ZER1 zyg-11 related, cell cycle regulator
ZNF334 zinc finger protein 334

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BEX1 brain expressed, X-linked 1
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF30 chromosome 11 open reading frame 30
C5 complement component 5
CAPN15 calpain 15
CCDC9 coiled-coil domain containing 9
CIR1 corepressor interacting with RBPJ, 1
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHDDS dehydrodolichyl diphosphate synthase
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
EFCAB2 EF-hand calcium binding domain 2
EGF epidermal growth factor
ERF Ets2 repressor factor
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXL6 F-box and leucine-rich repeat protein 6
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FOXC1 forkhead box C1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GMEB1 glucocorticoid modulatory element binding protein 1
GRAMD1B GRAM domain containing 1B
GSR glutathione reductase
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
HOMER2 homer scaffolding protein 2
HOXA6 homeobox A6
IL11RA interleukin 11 receptor, alpha
IL15RA interleukin 15 receptor, alpha
INO80D INO80 complex subunit D
IRF6 interferon regulatory factor 6
KRT6A keratin 6A, type II
LIMS2 LIM and senescent cell antigen-like domains 2
LZTR1 leucine-zipper-like transcription regulator 1
MAP7D1 MAP7 domain containing 1
MAPK12 mitogen-activated protein kinase 12
MAST3 microtubule associated serine/threonine kinase 3
MATN3 matrilin 3
MFGE8 milk fat globule-EGF factor 8 protein
MICALL2 MICAL-like 2
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NDRG4 NDRG family member 4
NT5M 5',3'-nucleotidase, mitochondrial
OVGP1 oviductal glycoprotein 1, 120kDa
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PALMD palmdelphin
PC pyruvate carboxylase
PCBP4 poly(rC) binding protein 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POMT2 protein-O-mannosyltransferase 2
PRMT7 protein arginine methyltransferase 7
PROSER1 proline and serine rich 1
PRPH peripherin
QTRT1 queuine tRNA-ribosyltransferase 1
RAB20 RAB20, member RAS oncogene family
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A3 S100 calcium binding protein A3
SCG2 secretogranin II
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC46A3 solute carrier family 46, member 3
SMG9 SMG9 nonsense mediated mRNA decay factor
SPAG4 sperm associated antigen 4
SPATA2L spermatogenesis associated 2-like
SSBP3 single stranded DNA binding protein 3
STX1A syntaxin 1A (brain)
TBL3 transducin (beta)-like 3
TCTN1 tectonic family member 1
TEAD3 TEA domain family member 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF2 transmembrane 7 superfamily member 2
TSC22D4 TSC22 domain family, member 4
URGCP upregulator of cell proliferation
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF528 zinc finger protein 528
ZNF675 zinc finger protein 675
ZNHIT2 zinc finger, HIT-type containing 2