ranitidine-6324 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the ranitidine-6324 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AMACR alpha-methylacyl-CoA racemase
APAF1 apoptotic peptidase activating factor 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARID1A AT rich interactive domain 1A (SWI-like)
ASTN2 astrotactin 2
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C15ORF39 chromosome 15 open reading frame 39
C7ORF43 chromosome 7 open reading frame 43
CD101 CD101 molecule
CD72 CD72 molecule
CLCN5 chloride channel, voltage-sensitive 5
CNR2 cannabinoid receptor 2 (macrophage)
COL11A2 collagen, type XI, alpha 2
COL16A1 collagen, type XVI, alpha 1
COLEC12 collectin sub-family member 12
CORT cortistatin
CREB3L1 cAMP responsive element binding protein 3-like 1
CREM cAMP responsive element modulator
CRYBA2 crystallin, beta A2
CTNND2 catenin (cadherin-associated protein), delta 2
ELMO2 engulfment and cell motility 2
EMP1 epithelial membrane protein 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERAP1 endoplasmic reticulum aminopeptidase 1
FBXO40 F-box protein 40
FGF1 fibroblast growth factor 1 (acidic)
FLOT2 flotillin 2
FRMD4A FERM domain containing 4A
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
HIST1H4E histone cluster 1, H4e
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INADL InaD-like (Drosophila)
INO80B INO80 complex subunit B
IRS2 insulin receptor substrate 2
KHK ketohexokinase (fructokinase)
KIAA1109 KIAA1109
KRT31 keratin 31, type I
KRT33A keratin 33A, type I
LIG4 ligase IV, DNA, ATP-dependent
LIMD1 LIM domains containing 1
LPAR4 lysophosphatidic acid receptor 4
LRRN2 leucine rich repeat neuronal 2
MAP1B microtubule-associated protein 1B
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK7 mitogen-activated protein kinase 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MED16 mediator complex subunit 16
MUC1 mucin 1, cell surface associated
NARFL nuclear prelamin A recognition factor-like
NCOR2 nuclear receptor corepressor 2
NDE1 nudE neurodevelopment protein 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOX1 NADPH oxidase 1
NPTXR neuronal pentraxin receptor
NR2E3 nuclear receptor subfamily 2, group E, member 3
PAX2 paired box 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA2 plexin A2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB1 proline-rich protein BstNI subfamily 1
PRB3 proline-rich protein BstNI subfamily 3
PWAR5 Prader Willi/Angelman region RNA 5
R3HCC1L R3H domain and coiled-coil containing 1-like
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SCARA3 scavenger receptor class A, member 3
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SETD8 SET domain containing (lysine methyltransferase) 8
SIDT2 SID1 transmembrane family, member 2
SLA Src-like-adaptor
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOX12 SRY (sex determining region Y)-box 12
SOX2 SRY (sex determining region Y)-box 2
SPAG8 sperm associated antigen 8
SPRR1A small proline-rich protein 1A
STAT5B signal transducer and activator of transcription 5B
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBX6 T-box 6
TCF15 transcription factor 15 (basic helix-loop-helix)
TEX15 testis expressed 15
TFEB transcription factor EB
TNPO2 transportin 2
TRA2A transformer 2 alpha homolog (Drosophila)
UBOX5 U-box domain containing 5
USB1 U6 snRNA biogenesis 1
USP2 ubiquitin specific peptidase 2
WIZ widely interspaced zinc finger motifs
ZNF276 zinc finger protein 276
ZNF358 zinc finger protein 358
ZNF440 zinc finger protein 440
ZNF484 zinc finger protein 484
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
AFAP1 actin filament associated protein 1
ALPK1 alpha-kinase 1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATF7IP2 activating transcription factor 7 interacting protein 2
C11ORF63 chromosome 11 open reading frame 63
C1ORF159 chromosome 1 open reading frame 159
CCDC85C coiled-coil domain containing 85C
CCNL2 cyclin L2
CDC37L1 cell division cycle 37-like 1
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTSF cathepsin F
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND4A DENN/MADD domain containing 4A
DET1 de-etiolated homolog 1 (Arabidopsis)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ECM1 extracellular matrix protein 1
EGLN2 egl-9 family hypoxia-inducible factor 2
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FBXL6 F-box and leucine-rich repeat protein 6
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FOXA1 forkhead box A1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GNL1 guanine nucleotide binding protein-like 1
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HOXC5 homeobox C5
HPS6 Hermansky-Pudlak syndrome 6
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KDM5C lysine (K)-specific demethylase 5C
KIAA0754 KIAA0754
LRRC37A3 leucine rich repeat containing 37, member A3
MAPK12 mitogen-activated protein kinase 12
MFSD12 major facilitator superfamily domain containing 12
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MITF microphthalmia-associated transcription factor
MT1M metallothionein 1M
MUC3B mucin 3B, cell surface associated
MYBBP1A MYB binding protein (P160) 1a
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDRG4 NDRG family member 4
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDIA3 protein disulfide isomerase family A, member 3
PEX26 peroxisomal biogenesis factor 26
PHACTR4 phosphatase and actin regulator 4
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POMT2 protein-O-mannosyltransferase 2
PPAN peter pan homolog (Drosophila)
PPT2 palmitoyl-protein thioesterase 2
PRAME preferentially expressed antigen in melanoma
PRKCD protein kinase C, delta
PROSER1 proline and serine rich 1
RAB3A RAB3A, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A4 S100 calcium binding protein A4
SCAI suppressor of cancer cell invasion
SCAMP5 secretory carrier membrane protein 5
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNTA1 syntrophin, alpha 1
SPEG SPEG complex locus
STAG3 stromal antigen 3
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMEM62 transmembrane protein 62
TMEM8A transmembrane protein 8A
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TTC4 tetratricopeptide repeat domain 4
TUBA3C tubulin, alpha 3c
TULP4 tubby like protein 4
USP21 ubiquitin specific peptidase 21
USP27X ubiquitin specific peptidase 27, X-linked
USP32 ubiquitin specific peptidase 32
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WBP2 WW domain binding protein 2
WDR46 WD repeat domain 46
ZNF16 zinc finger protein 16
ZNF557 zinc finger protein 557
ZNF623 zinc finger protein 623
ZNF816 zinc finger protein 816