racecadotril-2774 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the racecadotril-2774 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD12 ankyrin repeat domain 12
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP10A ATPase, class V, type 10A
B9D2 B9 protein domain 2
BAX BCL2-associated X protein
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C11ORF30 chromosome 11 open reading frame 30
CCDC69 coiled-coil domain containing 69
CCDC71 coiled-coil domain containing 71
CCL5 chemokine (C-C motif) ligand 5
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDON cell adhesion associated, oncogene regulated
CES3 carboxylesterase 3
COL13A1 collagen, type XIII, alpha 1
COL5A1 collagen, type V, alpha 1
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DSC2 desmocollin 2
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EXOSC1 exosome component 1
FBXO21 F-box protein 21
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FRMD4A FERM domain containing 4A
GMPR guanosine monophosphate reductase
GPER1 G protein-coupled estrogen receptor 1
GSDMD gasdermin D
GSK3A glycogen synthase kinase 3 alpha
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HCAR3 hydroxycarboxylic acid receptor 3
HIRA histone cell cycle regulator
HLA-F major histocompatibility complex, class I, F
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOMER3 homer scaffolding protein 3
HOXB7 homeobox B7
IDS iduronate 2-sulfatase
IL11 interleukin 11
IL1B interleukin 1, beta
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KRT19P2 keratin 19 pseudogene 2
KRT6B keratin 6B, type II
LAMB1 laminin, beta 1
LAT2 linker for activation of T cells family, member 2
LMNB1 lamin B1
LRRC14 leucine rich repeat containing 14
LRRC23 leucine rich repeat containing 23
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MID1 midline 1
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NCR2 natural cytotoxicity triggering receptor 2
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NUP188 nucleoporin 188kDa
OLFML2A olfactomedin-like 2A
OR1D2 olfactory receptor, family 1, subfamily D, member 2
ORAI2 ORAI calcium release-activated calcium modulator 2
P3H1 prolyl 3-hydroxylase 1
PCDHGA8 protocadherin gamma subfamily A, 8
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLXNC1 plexin C1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
QPCTL glutaminyl-peptide cyclotransferase-like
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RGS10 regulator of G-protein signaling 10
RGS14 regulator of G-protein signaling 14
RHOH ras homolog family member H
RIMS3 regulating synaptic membrane exocytosis 3
RND1 Rho family GTPase 1
RNF39 ring finger protein 39
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35G2 solute carrier family 35, member G2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLPI secretory leukocyte peptidase inhibitor
SOX5 SRY (sex determining region Y)-box 5
SPTBN5 spectrin, beta, non-erythrocytic 5
STMN1 stathmin 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TEX40 testis expressed 40
THBS3 thrombospondin 3
TM2D1 TM2 domain containing 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRADD TNFRSF1A-associated via death domain
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TTC39A tetratricopeptide repeat domain 39A
USB1 U6 snRNA biogenesis 1
WDR1 WD repeat domain 1
XDH xanthine dehydrogenase
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACTL8 actin-like 8
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARSB arylsulfatase B
ASAP1-IT1 ASAP1 intronic transcript 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BCL7B B-cell CLL/lymphoma 7B
C1ORF54 chromosome 1 open reading frame 54
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMK1D calcium/calmodulin-dependent protein kinase ID
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBX8 chromobox homolog 8
CCP110 centriolar coiled coil protein 110kDa
CD53 CD53 molecule
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHKB choline kinase beta
CHM choroideremia (Rab escort protein 1)
CLDND1 claudin domain containing 1
CLSPN claspin
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL4A5 collagen, type IV, alpha 5
COTL1 coactosin-like F-actin binding protein 1
CRY2 cryptochrome circadian clock 2
CUZD1 CUB and zona pellucida-like domains 1
DGAT1 diacylglycerol O-acyltransferase 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM3 dynamin 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETNK2 ethanolamine kinase 2
FAM212B family with sequence similarity 212, member B
FAM76A family with sequence similarity 76, member A
FBRS fibrosin
FKBP10 FK506 binding protein 10, 65 kDa
FOXI1 forkhead box I1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L galactosidase, beta 1-like
GLI3 GLI family zinc finger 3
GPR27 G protein-coupled receptor 27
GSTA4 glutathione S-transferase alpha 4
HMG20A high mobility group 20A
HOXC11 homeobox C11
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA2 heat shock 70kDa protein 2
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IRF7 interferon regulatory factor 7
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLHL25 kelch-like family member 25
KRI1 KRI1 homolog (S. cerevisiae)
LAMB3 laminin, beta 3
LOC390998 ribosomal protein L10 pseudogene
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MXD3 MAX dimerization protein 3
NCALD neurocalcin delta
NTF3 neurotrophin 3
PARPBP PARP1 binding protein
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PLXNA3 plexin A3
PMEL premelanosome protein
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RLN1 relaxin 1
RNF2 ring finger protein 2
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SCRN3 secernin 3
SLC22A14 solute carrier family 22, member 14
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLIT2 slit homolog 2 (Drosophila)
SOX3 SRY (sex determining region Y)-box 3
STON1 stonin 1
TESK2 testis-specific kinase 2
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TSPAN5 tetraspanin 5
TSPYL2 TSPY-like 2
TTC23 tetratricopeptide repeat domain 23
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
TWISTNB TWIST neighbor
USP19 ubiquitin specific peptidase 19
VAX2 ventral anterior homeobox 2
VEZT vezatin, adherens junctions transmembrane protein
VLDLR very low density lipoprotein receptor
WDR25 WD repeat domain 25
XYLT2 xylosyltransferase II
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF282 zinc finger protein 282
ZNF428 zinc finger protein 428
ZNF532 zinc finger protein 532
ZNF639 zinc finger protein 639
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZSCAN31 zinc finger and SCAN domain containing 31