rac guanyl-nucleotide exchange factor activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rac family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. (Gene Ontology, GO_0030676)
External Link http://amigo.geneontology.org/amigo/term/GO:0030676
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Genes

12 genes performing the rac guanyl-nucleotide exchange factor activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
DOCK2 dedicator of cytokinesis 2
EPS8L1 EPS8-like 1
EPS8L2 EPS8-like 2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
SPATA13 spermatogenesis associated 13
TIAM1 T-cell lymphoma invasion and metastasis 1
VAV1 vav 1 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor