quipazine-7240 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the quipazine-7240 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AICDA activation-induced cytidine deaminase
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP9B ATPase, class II, type 9B
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAG4 BCL2-associated athanogene 4
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C9ORF9 chromosome 9 open reading frame 9
CA5BP1 carbonic anhydrase VB pseudogene 1
CALD1 caldesmon 1
CAPN15 calpain 15
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD70 CD70 molecule
CENPO centromere protein O
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CPD carboxypeptidase D
DIO2 deiodinase, iodothyronine, type II
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK4 docking protein 4
DRD2 dopamine receptor D2
ELOVL2 ELOVL fatty acid elongase 2
EMID1 EMI domain containing 1
ETV6 ets variant 6
FCF1 FCF1 rRNA-processing protein
FLJ21369 uncharacterized protein FLJ21369
FRMPD1 FERM and PDZ domain containing 1
FZD9 frizzled class receptor 9
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR68 G protein-coupled receptor 68
GSTA1 glutathione S-transferase alpha 1
HCG4 HLA complex group 4 (non-protein coding)
HIST1H2AL histone cluster 1, H2al
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHMBP2 immunoglobulin mu binding protein 2
IGL immunoglobulin lambda locus
IL1A interleukin 1, alpha
INHBE inhibin, beta E
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM8 lysine (K)-specific demethylase 8
KHSRP KH-type splicing regulatory protein
KLHL22 kelch-like family member 22
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT6B keratin 6B, type II
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MERTK MER proto-oncogene, tyrosine kinase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MXD4 MAX dimerization protein 4
MYO7A myosin VIIA
NCR2 natural cytotoxicity triggering receptor 2
NF1 neurofibromin 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OASL 2'-5'-oligoadenylate synthetase-like
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVOL1 ovo-like zinc finger 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF20 PHD finger protein 20
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHTF2 putative homeodomain transcription factor 2
PITX1 paired-like homeodomain 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RLN1 relaxin 1
SCARB2 scavenger receptor class B, member 2
SDC3 syndecan 3
SEC24D SEC24 family member D
SERHL2 serine hydrolase-like 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNN stannin
ST14 suppression of tumorigenicity 14 (colon carcinoma)
SYBU syntabulin (syntaxin-interacting)
TESC tescalcin
THBD thrombomodulin
TMEM19 transmembrane protein 19
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF3IP3 TRAF3 interacting protein 3
TSHR thyroid stimulating hormone receptor
UBTD1 ubiquitin domain containing 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VNN2 vanin 2
VPREB3 pre-B lymphocyte 3
XYLB xylulokinase homolog (H. influenzae)
YY2 YY2 transcription factor
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
ASB9 ankyrin repeat and SOCS box containing 9
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
BBS10 Bardet-Biedl syndrome 10
BPGM 2,3-bisphosphoglycerate mutase
BRAF B-Raf proto-oncogene, serine/threonine kinase
C11ORF80 chromosome 11 open reading frame 80
C16ORF59 chromosome 16 open reading frame 59
CAMKMT calmodulin-lysine N-methyltransferase
CASD1 CAS1 domain containing 1
CD302 CD302 molecule
CDR2L cerebellar degeneration-related protein 2-like
CEP72 centrosomal protein 72kDa
CEP97 centrosomal protein 97kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN15 claudin 15
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CTNNBIP1 catenin, beta interacting protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP2 dual specificity phosphatase 2
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
FAM131A family with sequence similarity 131, member A
FANCC Fanconi anemia, complementation group C
FBRS fibrosin
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FZD4 frizzled class receptor 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GLI3 GLI family zinc finger 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HHLA3 HERV-H LTR-associating 3
HMBOX1 homeobox containing 1
HS1BP3 HCLS1 binding protein 3
IL4R interleukin 4 receptor
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0125 KIAA0125
KIAA0232 KIAA0232
KLHL25 kelch-like family member 25
LOC257152 uncharacterized LOC257152
LRP3 low density lipoprotein receptor-related protein 3
LRRC8E leucine rich repeat containing 8 family, member E
LYRM9 LYR motif containing 9
MBOAT2 membrane bound O-acyltransferase domain containing 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MSL1 male-specific lethal 1 homolog (Drosophila)
MXD3 MAX dimerization protein 3
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFE2L3 nuclear factor, erythroid 2-like 3
NUBPL nucleotide binding protein-like
NUP62CL nucleoporin 62kDa C-terminal like
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHB3 protocadherin beta 3
PCDHGB5 protocadherin gamma subfamily B, 5
PDE12 phosphodiesterase 12
PECR peroxisomal trans-2-enoyl-CoA reductase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
RAB23 RAB23, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
REPS2 RALBP1 associated Eps domain containing 2
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCAI suppressor of cancer cell invasion
SH2D4A SH2 domain containing 4A
SIK1 salt-inducible kinase 1
SKA1 spindle and kinetochore associated complex subunit 1
STBD1 starch binding domain 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYCP2 synaptonemal complex protein 2
TAZ tafazzin
TBX19 T-box 19
TGFBI transforming growth factor, beta-induced, 68kDa
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TXLNG taxilin gamma
USP27X ubiquitin specific peptidase 27, X-linked
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGF VGF nerve growth factor inducible
VWA1 von Willebrand factor A domain containing 1
WDR62 WD repeat domain 62
WWC2 WW and C2 domain containing 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB39 zinc finger and BTB domain containing 39
ZBTB6 zinc finger and BTB domain containing 6
ZNF33B zinc finger protein 33B
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668
ZNF767P zinc finger family member 767, pseudogene
ZNF8 zinc finger protein 8