quinostatin-973 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the quinostatin-973 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADCK3 aarF domain containing kinase 3
AGBL5 ATP/GTP binding protein-like 5
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALMS1 Alstrom syndrome protein 1
APLP2 amyloid beta (A4) precursor-like protein 2
APOE apolipoprotein E
ARL4C ADP-ribosylation factor-like 4C
ATP9A ATPase, class II, type 9A
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BMP1 bone morphogenetic protein 1
BTG2 BTG family, member 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
CALCOCO1 calcium binding and coiled-coil domain 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CBX7 chromobox homolog 7
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CFLAR CASP8 and FADD-like apoptosis regulator
CLCN6 chloride channel, voltage-sensitive 6
CRELD1 cysteine-rich with EGF-like domains 1
CUL9 cullin 9
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBP D site of albumin promoter (albumin D-box) binding protein
DNAAF1 dynein, axonemal, assembly factor 1
DSCAM Down syndrome cell adhesion molecule
DVL3 dishevelled segment polarity protein 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM118A family with sequence similarity 118, member A
FAM174B family with sequence similarity 174, member B
FKBP10 FK506 binding protein 10, 65 kDa
GOLGA2 golgin A2
GRB7 growth factor receptor-bound protein 7
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HBP1 HMG-box transcription factor 1
HFE hemochromatosis
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IRS2 insulin receptor substrate 2
ITFG2 integrin alpha FG-GAP repeat containing 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL24 kelch-like family member 24
LHX6 LIM homeobox 6
LOC100272216 uncharacterized LOC100272216
LOC644450 uncharacterized LOC644450
LPP LIM domain containing preferred translocation partner in lipoma
LRRC20 leucine rich repeat containing 20
LRRC40 leucine rich repeat containing 40
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MED6 mediator complex subunit 6
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MST1 macrophage stimulating 1
MT1G metallothionein 1G
MXD3 MAX dimerization protein 3
MZT2B mitotic spindle organizing protein 2B
NADK NAD kinase
NCOA2 nuclear receptor coactivator 2
NUP210 nucleoporin 210kDa
PDCD2 programmed cell death 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PNRC1 proline-rich nuclear receptor coactivator 1
PTK6 protein tyrosine kinase 6
PVT1 Pvt1 oncogene (non-protein coding)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RABGAP1 RAB GTPase activating protein 1
RECQL5 RecQ protein-like 5
RFTN1 raftlin, lipid raft linker 1
RNASEH2B ribonuclease H2, subunit B
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RTN2 reticulon 2
SGSH N-sulfoglucosamine sulfohydrolase
SGSM2 small G protein signaling modulator 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMAD3 SMAD family member 3
SOX4 SRY (sex determining region Y)-box 4
SPN sialophorin
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SUGP1 SURP and G patch domain containing 1
SYT12 synaptotagmin XII
SZT2 seizure threshold 2 homolog (mouse)
TAOK1 TAO kinase 1
TBC1D17 TBC1 domain family, member 17
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBKBP1 TBK1 binding protein 1
TJAP1 tight junction associated protein 1 (peripheral)
TM4SF1 transmembrane 4 L six family member 1
TMEM53 transmembrane protein 53
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK1 tyrosine kinase, non-receptor, 1
ULK2 unc-51 like autophagy activating kinase 2
UNC5B unc-5 homolog B (C. elegans)
USB1 U6 snRNA biogenesis 1
WDR19 WD repeat domain 19
ZMYM2 zinc finger, MYM-type 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF16 zinc finger protein 16
ZNF446 zinc finger protein 446
ZNF710 zinc finger protein 710
ZNF721 zinc finger protein 721

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACAD8 acyl-CoA dehydrogenase family, member 8
AMD1 adenosylmethionine decarboxylase 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ASTE1 asteroid homolog 1 (Drosophila)
ATAD2B ATPase family, AAA domain containing 2B
ATAD5 ATPase family, AAA domain containing 5
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAGE B melanoma antigen
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C9ORF40 chromosome 9 open reading frame 40
CA2 carbonic anhydrase II
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCNE2 cyclin E2
CCNJ cyclin J
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CEP72 centrosomal protein 72kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLDND1 claudin domain containing 1
CNOT6 CCR4-NOT transcription complex, subunit 6
CORO1A coronin, actin binding protein, 1A
CRY1 cryptochrome circadian clock 1
CUTC cutC copper transporter
DBR1 debranching RNA lariats 1
DDA1 DET1 and DDB1 associated 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
EFHD2 EF-hand domain family, member D2
EGLN3 egl-9 family hypoxia-inducible factor 3
EML4 echinoderm microtubule associated protein like 4
EXOC5 exocyst complex component 5
FASTKD3 FAST kinase domains 3
FASTKD5 FAST kinase domains 5
FBXO5 F-box protein 5
FIP1L1 factor interacting with PAPOLA and CPSF1
FKBP5 FK506 binding protein 5
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDAP1 ganglioside induced differentiation associated protein 1
GHR growth hormone receptor
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2I general transcription factor IIi
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HCCS holocytochrome c synthase
HCFC2 host cell factor C2
HIRA histone cell cycle regulator
HIST1H2AE histone cluster 1, H2ae
HIST1H2AJ histone cluster 1, H2aj
HP1BP3 heterochromatin protein 1, binding protein 3
HPS6 Hermansky-Pudlak syndrome 6
IFRD1 interferon-related developmental regulator 1
INSIG2 insulin induced gene 2
KCTD20 potassium channel tetramerization domain containing 20
KLC2 kinesin light chain 2
KPNA4 karyopherin alpha 4 (importin alpha 3)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMNB1 lamin B1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP6D1 MAP6 domain containing 1
MIR22HG MIR22 host gene
MRPL39 mitochondrial ribosomal protein L39
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NPY5R neuropeptide Y receptor Y5
PAQR3 progestin and adipoQ receptor family member III
PCBP4 poly(rC) binding protein 4
PNO1 partner of NOB1 homolog (S. cerevisiae)
PPIF peptidylprolyl isomerase F
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
RAB23 RAB23, member RAS oncogene family
RANBP6 RAN binding protein 6
RGS17 regulator of G-protein signaling 17
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC25A40 solute carrier family 25, member 40
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5)
SNX15 sorting nexin 15
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TGDS TDP-glucose 4,6-dehydratase
TIGAR TP53 induced glycolysis regulatory phosphatase
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TPST1 tyrosylprotein sulfotransferase 1
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZMAT5 zinc finger, matrin-type 5